Prostate cancer screening recommendations based on age and PSA levels, adapted from the National Comprehensive Cancer Network Clinical Practice Guidelines In Oncology (NCCN Guidelines®) for Prostate Cancer Early Detection.
Prostate Cancer Early Detection: Age Recommendations and PSA Levels Chart
Discuss benefits and risks of prostate cancer screening with your doctor
Age 40-75 for high-risk individuals, including:
Have a baseline PSA and consider a baseline DRE
•Black/African Americans
Average-risk individuals: • If PSA is less than 1 ng/mL and DRE normal (if done), repeat testing every 2 – 4 years • If PSA is 1 – 3 ng/mL and DRE normal (if done), repeat testing every 1 – 2 years • If PSA is more than 3 ng/mL and/or a very suspicious DRE, talk with your doctor about further testing High-risk individuals: • If PSA is less than or equal to 3 ng/mL and DRE normal (if done), repeat testing every 1 – 2 years • If PSA is more than 3 ng/mL and/or a very suspicious DRE, talk with your doctor about further testing
•Those with genetic mutations that increase the risk for prostate cancer
•Those with concerning family or personal history of cancer
Age 45-75 for average-risk individuals
Talk with your doctor about if prostate cancer screening should continue. Testing after age 75 is recommended only in very healthy individuals.
Age 75+
If screened, and PSA is 4 ng/mL or more, or a very suspicious DRE, talk with your doctor about further testing
Based on National Comprehensive Cancer Network ® Clinical Practice Guidelines in Oncology (NCCN Guidelines ® ) for Prostate Cancer Early Detection 2025
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