Heterologous titres (Indicators of cross-protection) from WRL Field isolates from 2020 onwards
Vaccine strains tested by the WRL
SAT2 ERI 98
SAT2 ZIM 83
SAT2/JOR/11/2023 SAT2/JOR/20/2023 SAT2/JOR/26/2023 SAT2/TUR/04/2023 SAT2/TUR/17/2023 SAT2/ALG/04/2023 SAT2/ALG/06/2023 SAT2/ETH/02/2022 SAT2/ETH/03/2022 SAT2/NIG/01/2021
SAT2/JOR/11/2023 SAT2/JOR/20/2023 SAT2/JOR/26/2023 SAT2/TUR/04/2023 SAT2/TUR/17/2023 SAT2/ALG/04/2023 SAT2/ALG/06/2023 SAT2/ETH/02/2022 SAT2/ETH/03/2022 SAT2/NIG/01/2021
High heterologous titre Good heterologous titre
Figure 3: The two SAT2 vaccine strains from BI generate satisfactory heterologous titers to combat the currently circulating SAT2 viruses. Source: http://www.wrlfmd.org
The concept of geographic pools has been instrumental in managing FMD. However, the emergence of Trans-pool movements poses new challenges that require further research and international cooperation. Understanding these movements and developing strategies to mitigate their impact is crucial for effective FMD management and control. The Trans-pool movement phenomenon underscores the importance of continuous surveillance, timely reporting, and the development of multivalent vaccines capable of protecting against multiple serotypes. It also highlights the need for global collaboration in sharing epidemiological data and resources to combat FMD effectively.
1. Risk of FMD disease SAT2 introduction and spread in countries in the Near East and West Eurasia. https://www.fao.org/3/cc8173en/cc8173en.pdf
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