Boehringer Ingelheim VPH TADtalk Global Newsletter Issue 2

To reduce risk laboratory and maintain preparedness, efforts are underway to improve training infrastructure and enhance national lab capacity for transboundary animal diseases diagnosis. Global surveillance is also being enhanced through funding to ANSES and IZSLER for sample collection, shipment, and data analysis. Research projects supported under the EU’s 10 th Fund for Applied Research (FAR) call are also contributing to these efforts. Conclusion Establishing the extinction of FMD serotype C is a significant milestone in disease control strategies. However, it also underscores the need for continued vigilance, research, and preparedness. As we move forward, the lessons learned from this initiative will undoubtedly inform our approach to managing other FMD serotypes and similar diseases.

1. Gathering evidence and measuring risk (2021-2022)

2. Reducing risks and maintaining preparedness (2023-2026)

Estimate confidence FMD-C is no longer circulating

Gather information regarding location and use of FMD-C materials

Activities to reduce risk of re-introduction

Promote contingency planning for FMD-C outbreaks

Communication & outreach with stakeholders

Figure 1: The FAO and WOAH task force activities towards establishing serotype extinction.

Source: WOAH-FAO FMD Ref Lab Network Report 2022.pdf (foot-and-mouth.org) https://foot-and-mouth.org/sites/foot/files/user-files/research-paper/pdf/11-23/WOAH-FAO%20FMD%20 Ref%20Lab%20Network%20Report%202022.pdf

Figure 2: Geographic and temporal distribution of historical FMDV serotype C events The map provides the most likely timing and spatial directionality of the historical events attributed to serotype C by examining historical information on outbreaks, the genetic relationship between sampled isolates and the results generated by the phylogeographic analysis. Reference: https://www.researchgate.net/publication/350214767_The_history_of_foot-and-mouth_disease_virus_serotype_C_ the_first_known_extinct_serotype#fullTextFileContent

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