Post Vaccination Monitoring (PVM): a win-win approach for enhancing FMD control strategies
Amélie Poulard Clinical Trials manager Veterinary Public Health Center
Dr Nicolas Denormandie Technical Service Director Veterinary Public Health Center
“Post-vaccination monitoring (PVM) is necessary to optimise the vaccination regimen and programme and the use of limited resources in attaining expected objectives. […] Demonstrating the impact of vaccination programmes on the disease burden helps to justify the vaccination cost, while identification of weaknesses in the vaccination programme enables improvements to be put in place.” This quotation illustrates the reasoning behind the creation of - The World Organisation for Animal Health WOAH/FAO guidelines for “Foot and mouth disease (FMD) vaccination and Post-vaccination monitoring (PVM).
PVM is process of an evaluation and monitoring conducted to meet diverse and specific objectives. These include assessing the efficacy of vaccine formulations, managing the logistics of vaccination campaigns, monitoring serological responses to vaccination, evaluating vaccination effectiveness during outbreaks, and gauging the success of the program in reducing virus circulation. This comprehensive approach contributes to the sustainable control of FMD at both farm and regional levels, whether in public or private sectors. The primary stakeholders in this process can be categorized into two principal groups. The first group comprises decision-makers who are tasked with clearly defining the objectives and allocating adequate resources. The second group consists of scientists who are responsible for devising appropriate methodologies that align with the defined objectives.
PVM is often narrowly associated with serological monitoring. However, the scope of PVM extends far beyond the mere assessment of vaccine effectiveness or efficacy. The primary concern of national veterinary departments lies in addressing the challenges posed by the vaccine, rather than merely the actions associated with its administration. Nevertheless, the evaluation of vaccination coverage remains a critical component of the process. The true value of PVM is derived from the integration of both vaccination coverage data and serological monitoring information.
Post Vaccination serological Monitoring
Reliable Assessment of vaccination coverage
National vet Services
Figure 1: The success of PVM relies on reliable assessment of vaccination coverage held by National vet authorities.
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