Boehringer Ingelheim VPH TADtalk Global Newsletter Issue 2

Press review section

Transboundary Animal Diseases (TADs) continue to pose significant threats to global livestock health. The research from the first half of this year has made significant strides in understanding disease mechanisms, improving diagnostic techniques, and developing effective vaccines for diseases such as Bluetongue Virus (BTV), Foot-and-Mouth Disease Virus (FMDV), and Peste des Petits Ruminants Virus (PPRV).

Dr Pascal HUDELET Head of Technical Services, Veterinary Public Health Center

Press review editorial

BTV The volume of publications related to BTV has been quite high, showing a renewed interest in orbiviruses, probably in link with the current European oubreaks. The majority of published studies focus on epidemiology of the disease and they cover multiple regions: Peru, Brazil, USA, Australia, Pakistan, Morocco, Tunisia, and of course Europe, with several papers dedicated to the recent BTV3 outbreak. Several of those papers highlight the role of various Culicoides species as vectors, with a particular focus on the impact of climate change on vector distribution and disease transmission. The financial impact of BTV, particularly in regions like Tunisia, has been a significant area of research. An interesting study from Bibard et al. evaluated the risk of dispersion of BTV3 from Sardinia and concluded that multiple areas of the Mediteranean Basin are at risk because Culicoides can be transported over long distances by winds.

A couple of publications are related to live vaccines -existing ones as well as future candidates: the full genome of the 15 strains included in the South African live vaccine has been published, and a recombinant BTV vaccine candidate expressing reporter genes has shown promising results in mice. These works are extremely relevant to Europe now considering the current BTV3 outbreak, helping us to better understand the virus we need to combat.

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