Self-administration with the EMPAVELI Injector
How do I take EMPAVELI? EMPAVELI is self-administered just under the skin using a small, thin needle that you never see with the EMPAVELI Injector. EMPAVELI is not an IV infusion (into the vein) that requires a healthcare provider to administer it for you. How often do I take EMPAVELI? EMPAVELI is taken 2 times a week* The injection takes approximately 30 to 60 minutes
See the EMPAVELI Injector Instructions for Use or, if using an infusion pump, see these specific Instructions for Use .
Avoid intense physical activity and do not bump or knock the EMPAVELI Injector or button during the injection. Keep your stomach totally dry.
If you miss a dose of EMPAVELI, take the missed dose as soon as possible. Take your next dose as regularly planned.
For ~30-60 minutes
*If there is an increase in your LDH, an enzyme in your blood, your healthcare provider may tell you to take EMPAVELI every 3 days.
If your healthcare provider decides to stop your treatment with EMPAVELI, follow their instructions for how to stop. Your healthcare provider will monitor you closely for at least 8 weeks after stopping treatment with EMPAVELI for any signs of hemolysis due to PNH.
watch the EMPAVELI Injector self-administration video
you get self-administration support from the start
there are processes for transitioning to EMPAVELI
certain vaccines are required before starting EMPAVELI
LDH=lactate dehydrogenase; PNH=paroxysmal nocturnal hemoglobinuria.
IMPORTANT SAFETY INFORMATION (cont’d) What is the most important information I should know about EMPAVELI? (cont'd) 2. If you have not completed your vaccines and EMPAVELI must be started right away, you should receive the required vaccines as soon as possible. 3. If you have not been vaccinated and EMPAVELI must be started right away, you should also receive antibiotics to take for as long as your healthcare provider tells you. 4. If you have been vaccinated against these bacteria in the past, you might need additional vaccines before starting EMPAVELI. Your healthcare provider will decide if you need additional vaccines.
Please see full Important Safety Information, including Boxed WARNING regarding risk of serious infections, on pages 38-39, and the full Prescribing Information and Medication Guide.
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