Self-administering EMPAVELI
How do I take EMPAVELI? EMPAVELI is self-administered just under the skin using a small, thin needle. EMPAVELI is not an IV infusion (into the vein) that requires a healthcare provider to administer it for you.
See the Instructions for Use .
Your healthcare provider will tell you how much EMPAVELI to infuse and how often to infuse. Do not infuse more or less than your healthcare provider tells you to.
How often do I take EMPAVELI? EMPAVELI is taken 2 times a week* The infusion takes about 30 minutes (if using 2 infusion sites) or 60 minutes (if using 1)
If you miss a dose of EMPAVELI, take the missed dose as soon as possible. Take your next dose as regularly planned.
If your healthcare provider decides to stop your treatment with EMPAVELI, follow their instructions for how to stop. Your healthcare provider will monitor you closely for at least 8 weeks after stopping treatment with EMPAVELI for any signs of hemolysis due to PNH.
*If there is an increase in your LDH, an enzyme in your blood, your healthcare provider may tell you to take EMPAVELI every 3 days.
watch the EMPAVELI self-administration video
you get self-administration support from the start
there are processes for transitioning to EMPAVELI
certain vaccines are required before starting EMPAVELI
LDH=lactate dehydrogenase; PNH=paroxysmal nocturnal hemoglobinuria.
Andrea is an adult with PNH taking EMPAVELI.
IMPORTANT SAFETY INFORMATION (cont’d) What is the most important information I should know about EMPAVELI? (cont'd) 2. If your healthcare provider decides that urgent treatment with EMPAVELI is needed, you should receive the required vaccinations as soon as possible. 3. If you have not been vaccinated and EMPAVELI therapy must be initiated immediately, you should also receive 2 weeks of antibiotics with your vaccinations. 4. If you have been vaccinated against these bacteria in the past, you might need additional vaccinations before starting EMPAVELI. Your healthcare provider will decide if you need additional vaccinations.
Please see full Important Safety Information, including Boxed WARNING regarding risk of serious infections, on pages 38-39, and the full Prescribing Information and Medication Guide.
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