STATE OF PSYCHEDELICS With Sean McAllister by the Editors Former cannabis attorney and leading psychedelics law ex- pert Sean McAllister explains how Colorado is once again the "Wild West," leading the country at an exciting time.
including LSD, psilocybin, MDMA, mes- caline, and others psychedelics are un- der some form of clinical trial. What about Colorado’s program? Right now it's psilocybin only in the regulated program. They've proposed adding iboga to the regulated system. It could be as early as next year or 2027 if everything was clean this year. Could be later. So by 2028 in Colorado we'll have regulated psilocybin and regulated iboga in healing centers. Again, it's expensive. $2,000 to 4,000 a journey for psilocybin. Iboga is probably going to be much more than that because there'll be a significant amount of medical monitoring around it. So that's in regulated Colorado. But the revolutionary thing we did in Colorado is we decriminalized four psy- chedelics, not just two: psilocybin, mes- caline (other than peyote, so San Pedro cactus are now decriminalized in Colora- do), DMT in all of it’s naturally occurring forms, and iboga. So for all four of those– there's no synthetics allowed–but nat- urally occurring psilocybin, mescaline, DMT, and iboga are legal to possess and
This country has come a long way in psychedelics. Where are we at the moment, and what’s the outlook? As we know, all the classic psyche- delics are schedule one substances under the Controlled Substances Act of 1970, and at the Federal level, the only psychedelic legal is ketamine. So that's why there's this proliferation of ketamine clinics around the country. Generally, it's recommended you should be under some kind of medical supervision when you're taking it. Ketamine's technically approved for an anesthetic–not for men- tal health conditions–but doctors and other prescribing medical professionals are prescribing it off-label for medical health conditions. It's in phase three clin- ical trials. People think in three to five years, we'll have MDMA federally, legally prescribed for treatment-resistant depression, and other mental health conditions. Psilo- cybin, also in phase-three clinical trials, three to five years, federally legal. We’ll have psilocybin, MDMA, ketamine and maybe others. All of classic psychedelics
16 MARCH/APRIL 2026
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