2026 Enlist Product Use Guide_Web

2026 PRODUCT USE GUIDE

ENLIST ® HERBICIDES — USED WITH ENLIST E3 ® SOYBEANS, ENLIST CORN AND ENLIST COTTON

What You’ll Find Inside: The Enlist ® weed control system

02 04 04 06 09

Crops with the Enlist ® trait

32 32 33 35 36 38 39 40 41 42 42 43

Enlist ® Ahead

Enlist E3 ® soybeans

Enlist ® herbicides

Enlist ® corn Enlist ® cotton

Cornerstone of a program approach Herbicides from Corteva Agriscience

Herbicide resistance management

The TruChoice ® offer

Potential crop response Pollinator protection Herbicide stewardship

Tank-mixing with glufosinate

12 13 15 22 26 28 29 30

Tank-mixing with Enlist ® herbicides

Nozzles

Technology Use Agreement (TUA)

Field planning

Trait stewardship

Temperature inversion Runoff mitigation Equipment cleanout Application summary

Enlist E3 ® soybean seed coat

Additional resources

This reference guide is not intended as a substitute for the product label for product(s) referenced herein. Always read and follow all label directions and precautions for use when using any pesticide alone or in tank-mix combination. Failure to follow the label, including any supplemental label precautions, is considered a misuse under federal law.

To find product labels and additional resources about the Enlist ® weed control system, visit Enlist.com or scan this QR code.

The Enlist ® weed control system

The Enlist ® weed control system is here for the long haul, and here’s why: It’s based in science and backed by stewardship. This unrivaled system starts with Enlist ® herbicide-tolerant traits that enable the use of our powerful Enlist ® herbicides. The Enlist ® Ahead management resource provides tools and training to make sure you get the most from the system.

Herbicide Tolerances

Bt Corn Products With Enlist ® Trait

Enlist E3 ® Soybeans

Enlist ® W3FE Cotton

Enlist ® W3E1 Cotton

2,4-D choline Glufosinate Glyphosate

2,4-D choline Glufosinate*

2,4-D choline Glufosinate Glyphosate

2,4-D choline

Glufosinate

FOP herbicides**

Glyphosate

* Non-Bt corn products with the Enlist ® trait may not contain glufosinate tolerance. See bag tag to verify herbicide tolerance. ** Not all FOP herbicides are labeled for use in Bt corn products with the Enlist ® trait. Before use, review the product label to ensure the product is labeled for use on Bt corn with the Enlist trait.

Straight-goods 2,4-D choline with additional tank-mix flexibility

Convenient proprietary blend of 2,4-D choline and glyphosate

Enlist One ® herbicide is a straight-goods 2,4-D choline product with Colex-D ® technology that provides additional tank-mix flexibility with products listed on EnlistTankMix.com, such as glufosinate herbicides, glyphosate herbicides, residual herbicides, fungicides and insecticides.

Enlist Duo ® herbicide with Colex-D technology combines the proven performance of 2,4-D choline and glyphosate in a convenient, proprietary blend.

States where Enlist Duo ® and Enlist One ® herbicides are registered:

Registered states

Demand for Enlist Duo is today less than 1% of total U.S. Enlist sales. We have therefore made the decision to stop U.S. production and sales of Enlist Duo. We are accepting orders for Enlist Duo for the 2026 season through November 15, 2025. This decision is the latest in a series of steps we have taken over the past few years to streamline our portfolio and does not affect the production or availability of Enlist One, which remains a market-leading solution. Following burndown, Enlist Duo and Enlist One herbicides with Colex-D ® technology are the only herbicides containing 2,4-D that are authorized for preemergence and postemergence use with Enlist ® crops. Consult Enlist ® herbicide labels for weed species controlled. Enlist Duo and Enlist One herbicides are not registered for use or sale in all states and counties; are not registered in AK, CA, CT, HI, ID, MA, ME, MT, NH, NV, OR, RI, UT, VT, WA and WY; and have additional subcounty restrictions in AL, GA, TN and TX, while existing county restrictions still remain in FL. All users must check “Bulletins Live! Two” no earlier than six months before using Enlist One or Enlist Duo herbicide. To obtain “Bulletins,” consult www.epa.gov/espp/ , call 844-447-3813 , or email espp@epa.gov . You must use the “Bulletin” valid for the month and state and county in which Enlist One or Enlist Duo herbicide are being applied. Contact your state pesticide regulatory agency if you have questions about the registration status of Enlist ® herbicides in your area. ALWAYS READ AND FOLLOW PESTICIDE LABEL DIRECTIONS. IT IS A VIOLATION OF FEDERAL AND STATE LAW TO USE ANY PESTICIDE PRODUCT OTHER THAN IN ACCORDANCE WITH ITS LABELING. ONLY USE FORMULATIONS THAT ARE SPECIFICALLY LABELED FOR SUCH USE IN THE STATE OF APPLICATION. USE OF PESTICIDE PRODUCTS, INCLUDING, WITHOUT LIMITATION, 2,4-D-CONTAINING PRODUCTS NOT AUTHORIZED FOR USE WITH ENLIST CROPS, MAY RESULT IN OFF-TARGET DAMAGE TO SENSITIVE CROPS/AREAS AND/OR SUSCEPTIBLE PLANTS, IN ADDITION TO CIVIL AND/OR CRIMINAL PENALTIES. Additional product-specific stewardship requirements for Enlist crops, including the Enlist Product Use Guide, can be found at TraitStewardship.com . Always read and follow label directions.

Enlist ® Herbicides

Get the Best Results

Enlist ® Ahead is a management resource that helps you get the best results from the Enlist ® weed control system while protecting the herbicide- tolerant technology for the future, helping you: • Make on-target applications on your crops. • Select and use different sites of action in the same growing season. • Mitigate herbicide resistance and prevent new As Part Of Enlist ® Ahead, You Can: • Download the Enlist ® Ahead app for readily accessible information on your iOS device. • Visit Enlist.com for an overview of the Enlist weed control system, an online training module and other technical information. • Visit EnlistTankMix.com for qualified tank-mix partner listings. • Get support from your local Corteva Agriscience crop protection territory manager. Following the best practices presented in Enlist Ahead will help you achieve optimum results and sustain the long-term performance of the Enlist ® weed control system. Growers of Enlist ® crops must read and follow the refuge and Insect Resistance Management (IRM) requirements in Product Use Guides found at TraitStewardship.com . resistance development in your fields (Learn more on this topic on Page 36).

Take control of tough weeds with Enlist Duo ® and Enlist One ® herbicides. Use Enlist ® herbicides as the cornerstone of a season-long program approach for weed management on crops with Enlist ® traits. Enlist ® herbicides control tough and herbicide-resistant weeds, including, but not limited to: Common ragweed Marestail* Morningglory Waterhemp* Pigweed* (including Palmer amaranth*) For a full list of the 90+ weeds controlled, reference the labels for Enlist Duo and Enlist One. Giant ragweed Lambsquarters Velvetleaf On-Target Characteristics Of 2,4-D Choline With Colex-D ® Technology How Enlist herbicides differ from 2,4-D ester, amine and other traditional formulations: • Near-zero volatility » 2,4-D choline is 96% less volatile than 2,4-D ester. » 2,4-D choline is 88% less volatile than 2,4-D amine.

• Reduced physical drift potential • Better handling characteristics

Use The Right Application Rate

Scan the QR code to find additional Product Use Guides.

Apply 4.75 pints of Enlist Duo ® herbicide or 2 pints of Enlist One ® herbicide per acre to young, actively growing weeds, according to the product label directions.** It’s essential to spray when weeds are 6 inches tall or less and to use the full herbicide rates. These practices help ensure best weed management and help prevent and mitigate the development of herbicide resistance.

* May require a broader management plan including timely application and use of a soil residual herbicide. ** Always read and follow the product label as well as state and local requirements.

Use Enlist ® Herbicides As The Cornerstone Of Your Program Approach

Key Practices To Remember: • Use full labeled rates for best weed management. • Spray when weeds are young, 6 inches tall or less. • Spray when weeds are actively growing.

Key Items To Remember: • Enlist ® herbicides can be used in burndown, preemergence and postemergence passes on crops with the Enlist ® trait. • Enlist herbicides are rainfast within four hours. • Up to three applications may be made per season (2 pt/A per application for Enlist One ® herbicide or 4.75 pt/A per application for Enlist Duo ® herbicide, where consistent with runoff management practices; see Page 28 for further information): » One application at burndown or preemergence » Up to two applications postemergence, at least 12 days apart • Always include a true broad-spectrum soil residual herbicide** in your weed management plan. • Consider using a layered residual, such as a Group 15 herbicide (e.g., acetochlor, S-metolachlor, pyraxasulfone), in your post passes for longer-lasting weed control. You’ll have the greatest success in weed management if you use an Enlist ® herbicide as part of a program approach for weed control in Enlist ® crops. This improves weed control, reduces weed competition during key stages of crop growth and helps manage herbicide resistance.

The product labels for Enlist Duo ® and Enlist One ® herbicides also contain important information about application equipment requirements, restrictions and precautions, and weed management.

Postemergence Application Rate

Enlist Duo ® herbicide

4.75 pt/A

Enlist One ® herbicide

2 pt/A

Postemergence Passes On Enlist ® Acres Enlist ® traits enable multiple options for postemergence herbicide sprays, allowing design of a program approach to fit each acre. Consider your weed pressure and agronomic situation when assessing which Enlist ® herbicide and tank-mix partners work best.

Enlist One ® herbicide

Enlist Duo ® herbicide Enlist Duo

+ Glufosinate

+ Glyphosate

Enlist One

4.75 pt/A

2 pt/A

* Only products tested and found to not adversely affect spray drift properties of Enlist herbicides may be tank-mixed with Enlist herbicides. Listed products may be found at www.EnlistTankMix.com. Listing on website does not imply agronomic recommendation or endorsement of use. ** Talk with your retailer for recommendations on preemergence and residual herbicides for your farm.

• Ammonium

• Glufosinate at 1x use rate • AMS at 1.5 – 3 lb/A

• Glyphosate at high rate • AMS as needed

sulfate (AMS) as needed

Check EnlistTankMix.com for all qualified AMS, glufosinate and glyphosate tank-mix products.*

Soybean Program Approach Soybean Program Approach

Apply Enlist ® Herbicides with Approved Tank-Mix Partners Apply Through R1 Growth Stage

Start Clean With Tillage Or Burndown

Plant Enlist E3 ® Soybeans

Apply A PRE Soil Residual Herbicide*

Tank-Mix With Approved Glyphosate Apply Through R1 Growth Stage

(No plantback restriction for Enlist E3 ® soybeans)

Tank-Mix A POST Soil Residual Herbicide with Enlist ® Herbicide † Apply Through R1 Growth Stage

(See label for plantback restriction)

Tank-Mix With Approved Glufosinate Apply Up To R1 Growth Stage

Tillage or burndown

Planting

Preemergence

Postemergence/tank-mix

VE VC

Corn Program Approach

Tank-Mix A POST Soil Residual Herbicide With Enlist ® Herbicide* †

Apply Enlist ® Herbicides No Larger Than V8 Growth Stage Or 30” Can Be Applied With Drop Nozzles From 30-48” High

Start Clean With Tillage Or Burndown

Plant Enlist ® Corn

Apply A PRE Soil Residual Herbicide

Tank-Mix With Approved Glyphosate No Larger Than V8 Growth Stage Or 30”

Tank-Mix With Approved Glufosinate Check Label For Growth Stage & Height Cutoff

(No plantback restriction for Enlist ® corn)

Atrazine

Tank-Mix With Assure II Herbicide ‡ From V2-V6 Growth Stage

* Visit EnlistTankMix.com for a full list of qualified tank-mix partners with Enlist One ® or Enlist Duo ® herbicides. Always reference product labels for application cut-off timing. † Kyro™ herbicide is not approved for tank-mix with Enlist Duo ® herbicide. ‡ Assure II herbicide is the only FOP herbicide currently labeled for post use on Enlist ® Corn.

Tillage or burndown

Planting

Preemergence

Postemergence/tank-mix

11” ht

20” ht

30” ht

Atrazine, FulTime NXT and Keystone NXT are Restricted Use Pesticides.

Cotton W3FE Program Approach Cotton W3FE Program Approach

Start Clean With Tillage Or Burndown

Plant Enlist ® Cotton

Apply A PRE Soil Residual Herbicide*

Apply Enlist ® Herbicides Apply Up To First White Bloom

(With glyphosate and glufosinate tolerance)

Tank-Mix With Approved Glyphosate Apply Up To 7 Days Prior To Harvest

Brake Cotoran Diuron Prowl Treflan Acetochlor Fluometuron Prometryn

(No plantback restriction for Enlist ® cotton)

Tank-Mix With Approved Glufosinate Apply Up To Early Bloom

Tank-Mix A POST Soil Residual Herbicide † Apply Up To 2-3 leaf stage

(See label for plantback restriction)

Tillage or burndown

Planting

Preemergence

Postemergence/tank-mix

Emergence

1st leaf

8th leaf 4th leaf

8th node

Mid bloom

Cotton W3E1 Program Approach Cotton W3E1 Program Approach

Start Clean With Tillage Or Burndown

Plant Enlist ® Cotton

Apply A PRE Soil Residual Herbicide*

Apply Enlist One ® Herbicide Apply Up To First White Bloom

Brake Cotoran Diuron Prowl Treflan Acetochlor Fluometuron Prometryn

(No glyphosate tolerance)

W3E1 Varieties Are Not Glyphosate-Tolerant DO NOT SPRAY GLYPHOSATE

(No plantback restriction for Enlist ® cotton)

Tank-Mix With Approved Glufosinate Apply Up To Early Bloom

Tank-Mix A POST Soil Residual Herbicide † Apply Up To 2-3 leaf stage

(See label for plantback restriction)

Tillage or burndown

Planting

Preemergence

Postemergence/tank-mix

Emergence

1st leaf

8th leaf 4th leaf

8th node

Mid bloom

Herbicide Partners Help Conquer Tough Weed Challenges Successful weed control means keeping weeds at bay throughout the growing season. The Enlist ® weed control system allows you to employ Enlist ® herbicides as the cornerstone of a program approach to overcome your toughest weed challenges. You also can incorporate preferred tank-mix partners and solutions from the industry-leading residual herbicide portfolio from Corteva Agriscience for season-long control.

Residual herbicides play a critical role in keeping fields of Enlist E3 ® soybeans, Enlist ® corn and Enlist ® cotton clean. Using high-quality, overlapping soil residuals introduces different sites of action and helps keep weed pressure in check, setting you up for success when making postemergence applications that include an Enlist ® herbicide. The Importance Of Residual Herbicides

Preferred Soybean Residual Herbicides:

Kyber ® Pro Sonic ® Sonic ® Boom

Enversa ™ Trivence ®

The preferred soybean herbicides from Corteva Agriscience offer diverse sites of action and extended residual activity for long- lasting weed control. These qualified tank-mix partners fit very well into a program approach to protect Enlist E3 ® soybeans.

Scan the QR code to find the right soybean residual herbicides to protect your acres.

Kyber ® Pro herbicide provides exceptional control of more than 50 broadleaf and grass weeds, including hard-to-control and ALS- and PPO-resistant weeds like Palmer amaranth and waterhemp. The new formulation also offers up to six weeks of residual activity. Three Sites Of Action: Metribuzin, flumioxazin, pyroxasulfone Application Flexibility: Apply up to three days postplant • Each individual site of action is effective against difficult, herbicide-resistant weeds Sonic ® Boom herbicide offers two powerful modes of action plus superior crop safety for clean fields and higher yield potential. This solution is especially effective against difficult, resistant broadleaves, including waterhemp, Palmer amaranth, marestail and kochia. Two Sites Of Action: Metribuzin, sulfentrazone

Preemergence Recommendation: Corn Belt, Northern Plains, Midsouth, KY, OH and MI

Preemergence Recommendation: Corn Belt, Great Plains, Midsouth, KY, OH and MI

Application Flexibility: Apply up to three days postplant • Comes in a convenient liquid premix for easy applications

Enversa ™ herbicide is a propriety encapsulated acetochlor that, once applied, drives to the soil, which creates a protective residual barrier and provides excellent crop safety. The new solution also offers a wide application window — preplant up to R1 on Enlist E3 ® soybeans and up to first bloom on cotton — to help navigate challenging weather conditions. • The residual tank-mix partner of choice for Enlist One ® herbicide. • Offers several weeks’ residual control of more than 25 broadleaf and grass weeds. • Labeled for use on multiple crops, including Enlist E3 soybeans, Enlist ® cotton and Enlist ® corn. Sonic ® herbicide is a trusted product that includes two sites of action, providing great residual efficacy on both large- and small-seeded broadleaf weeds as well as offering grass suppression. Plus, you get the flexibility to apply Sonic herbicide up to three days postplant. Two Sites Of Action: Sulfentrazone, cloransulam Application Flexibility: Spray up to three days postplant • Works in a tank mix with Enlist Duo ® or Enlist One ® herbicide Trivence ® herbicide offers three sites of action to deliver reliable control of challenging broadleaf weeds in soybeans while helping preserve the efficacy of existing herbicide options. It’s effective against Palmer amaranth, marestail, waterhemp, giant ragweed, morningglory, common lambsquarters and more. Three Sites Of Action: Chlorimuron, flumioxazin, metribuzin • Use for burndown and residual control

Preemergence Recommendation: Corn Belt and Great Plains

Postemergence Recommendation: Soybean tank-mix residual with Enlist One ® herbicide

Preemergence Recommendation: Midsouth, Kentucky, Ohio and Michigan

Preferred Corn Residual Herbicides:

Resicore ® Rev Kyro ®

Resicore ® REV and Kyro ® herbicides each offer multiple modes of action, diverse sites of action and extended residual activity, and they fit very well into a program approach to protect Enlist ® corn.

Resicore ® REV herbicide offers the proven, powerful weed control farmers have come to expect from Resicore ® herbicide in a high-performance formulation that offers supercharged tank-mix compatibility and boosted crop safety. Plus, Resicore ® REV herbicide can be applied preplant, pre- or postemergence on corn up to 24 inches tall, providing the flexibility to handle application delays.

Preemergence Recommendation: Corn Belt, Great Plains, MI, OH, KY and Midsouth.

Three Sites Of Action: Acetochlor, mesotrione, clopyralid Application Flexibility: Spray on corn up to 24 inches tall

Kyro ® herbicide is a postemergence solution that combines three unique sites of action to control more than 65 troublesome broadleaf and grass weed varieties. This novel formulation is the first to offer acetochlor, clopyralid and topramezone together in one convenient premix, providing farmers another powerful option outside of

glyphosate and ALS herbicides to control resistant grasses. Three Sites Of Action: Acetochlor, clopyralid, topramezone Application Flexibility: Spray on corn up to 24 inches tall • Works in a tank mix with Enlist One ® herbicide

Postemergence Recommendation: Corn Belt, Great Plains and Midsouth

Scan the QR code to find the right corn residual herbicides to protect your acres.

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*A minimum of $5,000 deposit is needed to open a TruChoice prepay account. Funds can be collected Oct. 1, 2025 – Feb. 27, 2026.

Tank-Mixing Enlist One ® Herbicide With Glufosinate*

Enlist.com/ WinningCombo

The primary Enlist One ® herbicide tank-mix recommendation is glufosinate for acres with high pressure of glyphosate-resistant broadleaf weeds, especially Palmer amaranth, waterhemp and kochia: • Most frequent tank-mix recommendation for the Cotton Belt, where higher levels of resistance and weed pressure are most prevalent. • Combination of Enlist One herbicide + glufosinate provides multiple unique, effective sites of action on crops with the Enlist ® trait.** • Because of the inherent stability of 2,4-D choline, adding glufosinate in the tank with Enlist One herbicide does not increase the potential for volatility due to acidification.

Optimizing a Tank-Mix Enlist One ® herbicide + Glufosinate* on Enlist ® crops Weed Height 3 inches tall or less

20 GPA is recommended for best performance of glufosinate, especially when grasses or dense weeds are present; 15 GPA minimum required with tank mix of Enlist One herbicide + glufosinate. Use 1.5 to 3 lb./A of AMS. May be any combination of qualified dry AMS, liquid AMS or AMS-containing products found on EnlistTankMix.com . Use nozzle and corresponding spray pressure from the qualified list for Enlist One herbicide. Optimize coverage with qualified nozzles by using a less coarse nozzle with a higher operating pressure, such as an AIXR or an AITTJ60. Avoid low humidity and cloudy conditions to maximize efficacy of glufosinate. Recommended spraying time is between 2 hours after dawn and 2 hours before sunset to maximize efficacy of glufosinate.

Carrier Volume

Adjuvants

Qualified Nozzle Selection

Know Your Rates: Enlist One herbicide: 2 pt/A (32 fl oz/A) Glufosinate: 1x rate/A Please refer to label for rate details based on crop and crop timing, weed species, weed size and weed density.*

Weather At Spray

Application Window For Glufosinate On Enlist ® Crops

Time Of Day

Enlist E3 ® soybeans

Up to R1

Wind Speed Maximum 10 mph

Enlist ® Corn**

Up to V6

PhytoGen ® Enlist ® Cotton

Up to early bloom or before 70 days prior to harvest

Even These Weeds Don’t Stand A Chance:

* See EnlistTankMix.com for further guidance on tankmixing with high-load glufosinate. ** Non- Bt corn products with the Enlist ® trait may not contain glufosinate tolerance. See bag tag to verify herbicide tolerance. † May require a broader management plan including timely application and use of a soil residual herbicide.

Palmer Amaranth †

Waterhemp †

Kochia †

Tank-Mixing With Enlist ® Herbicides*

Tank-Mix Sequence Procedures Start with a clean sprayer before mixing a load with Enlist One ® or Enlist Duo ® herbicide. • Begin with half-full tank of water carrier. • Begin agitation and continue throughout mixing process. Add products one at a time, in the following order: 1. AMS/water-conditioning agents 2. Preslurry water-soluble packets 3. Wettable powders/dry flowables 4. Compatibility agents 5. Liquid flowables 6. Capsule suspension (CS) or suspension emulsion (SE) » Such as acetochlor in Enversa ™ herbicide, a capsule suspension 7. Emulsifiable concentrate (EC) » Such as S-metolachlor in EverpreX ® herbicide 8. Soluble liquids (SL)

Applying An Enlist ® Herbicide In A Tank Mix With Other Products

The application window for an Enlist ® herbicide offers opportunities for tank mixes with other qualified products, such as other herbicides, insecticides, fungicides, micronutrients and adjuvants. Key Items To Remember: • A tank mix of an Enlist ® herbicide with other qualified herbicides provides multiple sites of action against tough weeds. Only use tank- mix partners listed on EnlistTankMix.com for every application of an Enlist herbicide. • For pigweed, waterhemp and kochia pressure,

farmers should consider a tank mix of Enlist One ® herbicide + glufosinate.

• For heavy grass pressure and glyphosate- susceptible broadleaves, farmers can either use Enlist Duo ® herbicide, a convenient blend of 2,4-D choline and glyphosate, or Enlist One herbicide + glyphosate. • Layering residual herbicides as part of a tank mix with Enlist herbicides helps provide season-long control of tough broadleaf weeds and grasses. • Farmers and applicators can select from many qualified ammonium sulfate (AMS) products and defoamers, as well as many other adjuvant options, listed on EnlistTankMix.com .

» Glyphosate products » Glufosinate products

» Enlist Duo ® herbicide at 4.75 pt/A » Enlist One ® herbicide at 2 pt/A

9. Crop oil concentrate (COC), methylated seed oil (MSO), nonionic surfactant (NIS), other adjuvants 10. Top off with water carrier

Ammonium Sulfate/Water-Conditioning Agents The addition of an AMS or water-conditioning agent helps maintain optimum performance of glufosinate and glyphosate products tank-mixed with Enlist ® herbicides on annual and perennial weeds, particularly under hard water conditions or drought conditions. The addition of AMS products does not affect the inherently low-volatility characteristics of the 2,4-D choline in Enlist herbicides. The most current list of qualified AMS and water- conditioning agents is available at EnlistTankMix.com . Anti-Foam/Defoamers The addition of an anti-foaming agent is highly encouraged for ease of mixing and sprayer cleanout. The most current list of qualified anti-foam/defoamers is available at EnlistTankMix.com .

Scan the QR code to download a tank-mix sequence fact sheet.

Note on mixing with glyphosate products: When mixing with Enlist One ® herbicide, do not pour glyphosate products into the tank or inductor at the same time as Enlist One herbicide and do not allow concentrated products to come into contact. Add products one at a time, allowing enough time for recirculation between additions of each separate product. Failure to add products one at a time, lack of sufficient water during mixing or not allowing sufficient agitation may result in salting out.

Tank-Mixing With Grass Herbicides When tank-mixing grass herbicides such as clethodim with Enlist One ® herbicide, increase the rate of the grass herbicide by a minimum of one-third to overcome potential antagonism. In addition, use recommended adjuvants for the grass herbicides. Do not exceed labeled rates with any recommended increase. To ensure the use of multiple sites of action for broadleaf control, include a broad-spectrum tank-mix partner or a sequential postemergence pass in your weed control program. Refer to all individual product labels, supplemental labeling and fact sheets for all products in the tank mixture, and observe all precautions and limitations on the labels, including application timing restrictions, soil restrictions, minimum plant-back interval and rotational guidelines. Use according to the most restrictive precautionary statements for each product in the tank mixture. In some cases, the addition of tank-mix products may cause increased crop response such as leaf speckling. Applications of emulsifiable concentrate products, or crop oils — including crop oil concentrates (COC), methylated seed oil (MSO), high surfactant oil concentrates (HSOC) and vegetable-based oils — are more likely to result in a crop response.

Check EnlistTankMix.com When Planning Your Application

Qualified Tank-Mix Partners

ARE: Products that passed the U.S. Environmental Protection Agency (EPA)-mandated drift testing protocol, which is part of the conditions of registration for Enlist ® herbicides. ARE NOT: • Tested for crop response • Tested for physical tank-mix compatibility

• An agronomic recommendation • An endorsement of any kind from Corteva Agriscience • An indicator of performance

As part of the conditions of registration for Enlist ® herbicides, the EPA established a tank-mix testing protocol. One reason the drift testing protocol exists is to protect sensitive areas, where endangered species may have a habitat, from spray drift. All qualified tank-mix products have passed established standards for spray performance. The most current list, which has the only tank-mix partners meeting the standards set by the EPA, is available at EnlistTankMix.com .

Scan the QR code to find qualified tank- mix partners for Enlist ® herbicides.

If you have further questions about proper handling and use of these products, or if you become aware of potential misuse or incidents involving these products, please contact Corteva Agriscience at 855-ENLIST1 (855-365-4781).

Enlist Duo ® and Enlist One ® herbicides are the only 2,4-D products authorized for use with Enlist ® crops. Following burndown, use of unauthorized 2,4-D products that are not Enlist herbicides on crops with the Enlist ® trait is not permitted.

Selecting The Right Nozzles To Optimize Coverage And Manage Drift

Key Items To Remember: • Use a qualified nozzle that provides the best possible coverage while appropriately managing spray droplets. • Use a minimum of 10 gallons of water carrier volume; 10 to 15 gallons recommended for Enlist ® herbicides. See Page 13 for information about tank-mixing Enlist One ® herbicide with glufosinate. • Take advantage of the flexibility provided by the listed nozzles and pressure ranges to select one that allows you to balance crop coverage and droplet size. • Only use nozzles and corresponding pressures listed on Enlist.com/Nozzles for every application of Enlist herbicides.*

Nozzles

The right nozzles can maximize product performance by managing the interaction between application volume, nozzle flow rate, nozzle type, operating pressure, ground speed, nozzle spacing and droplet size category.

Scan the QR code to find qualified nozzles for Enlist ® herbicides.

* Always read and follow the product label as well as state and local requirements.

Qualified Nozzles with Pressure Ranges (PSI)

Pressure Range (PSI)

Pressure Min Max

Nozzle Type Size

Manufacturer

110.04 110.06 110025 11003 11004 11005 11006

20 30 20 35 40 60 40 80 40 90 40 90 40 90

ABJ Agri

ABJ

AlbuZ

AVI

Greeneye Technology

25-03

GEE

20 80

11003 11004 11005 11006

15 30 15 35 15 40 15 35

TADF

30 60

025-D 03-D 04-D 05-D 06-D 11003 11004 11005 11006 11008

30 90 30 90 30 90 30 90 30 90 30 80 30 80 30 85 30 90 30 90

TADF-D

TDXL

Greenleaf

11002-D 30 90 110025-D 30 80 11003-D 30 70 11004-D 30 90 11006-D 30 90 11008-D 30 100

TDXL-D

110-04 110-05 110-06 110-08 110-10

20 90 20 85 20 40 20 80 20 80 20 35 20 50 20 60 20 60 20 50 20 55 20 50 20 60 20 75 20 30 20 80 20 70 20 65 20 40 30 85 30 90 30 85 30 85 30 85

03 05 06 08 10

PULSE GUARD SL- PWMG120

80-03 80-04 80-05 80-06 120-03 120-04 120-05 120-06 120-08 130-03 130-04 130-05 130-06 130-08

TRD

HyPro

ULD

ULDM

Coverage guide (factor of type, size and/or pressure range): Provides best balance of coverage and drift control Provides additional drift control by creating larger droplets No classification

For PWM Systems: NOZZLE Designed for use with PWM systems NOZZLE Use with John Deere ExactApply ™ system ONLY

Qualified Nozzles Enlist One ® herbicide

Pressure Range (PSI)

Pressure Min Max

Nozzle Type Size

Manufacturer

2003 2005 2006 2008 2010

20 35 20 50 20 60 20 60 20 50 20 80 20 80 20 80 20 80 20 80 20 80 30 80 30 70 20 30 20 80 20 70 20 65 20 40 30 85 30 90 30 85 30 85 30 85 20 60 20 80 20 80 30 80 30 80 30 80 30 80 30 80 30 80 30 75 30 80 30 80 30 80 30 80 30 80 30 80 30 80 30 80 30 80 30 80 30 80 30 80 20 25 20 50 20 50 20 60 20 60 20 65 20 55 15 30 15 55 15 60 15 30 15 60 15 60 15 60 15 70 15 75

PSLDM/ PSLDMQ

6003-R4 6004-R4 6005-R4 6006-R4 8004-R4 8005-R4 8006-R4 8008-R4

PSTSL

John Deere

2003 2004 2005 2006 2008 3003 3004 3005 3006 3008

PSULD/ PSULDQ

PSULDM/ PSULDMQ

120-03 120-04 120-05

Lechler

65-02E 65-025E 65-03E 65-04E 65-05E 65-06E 80-02 80-025

80-03 80-04 80-05 80-06

110-02 110-025 110-03 110-04 110-05 110-06 110-08 110-03 110-04 110-05 110-06 110-08 110-10 110-15 8003VK 8004VK 8005VK 110-03 110-04 110-05 110-06 110-08 110-10

TeeJet

AITTJ60

AIXR

Coverage guide (factor of type, size and/or pressure range): Provides best balance of coverage and drift control Provides additional drift control by creating larger droplets No classification

For PWM Systems: NOZZLE Designed for use with PWM systems NOZZLE Use with John Deere ExactApply ™ system ONLY

Qualified Nozzles Enlist One ® herbicide

Pressure Range (PSI)

Pressure Min Max 20 90 20 90 20 90 20 90 20 90 20 90 20 90 20 75 20 75 20 75 20 75 15 80 15 80 15 80 15 80 15 80 15 80 15 65 15 65 15 70 15 75 15 65 15 65 15 70 30 50 30 50 30 70 30 80 30 70 30 120 30 120

Nozzle Type Size

Manufacturer

110-02 110-025 110-03 110-04 110-05 110-06 110-08 6503SS 6504SS 6505SS 6506SS 110-02 110-025 110-03 110-04 110-05 110-06 110-08 110-10 110-03 110-04 110-05 110-06 110-08 110-03 110-04 110-05 110-06 110-08 110-10 110-125

APTJ

DGX

TeeJet

TTI

TTI60

40-08

20 70

80-04 80-05 80-06 80-08 80-10 80-125 110-04 110-05 110-06 110-08 110-10 110-125 80-06 80-08 80-10 80-125 110-03 110-04 110-05 110-06 110-08 110-10

25 40 25 45 25 70 25 70 25 70 25 70 25 30 25 35 25 60 25 70 25 70 25 70 25 25 25 60 25 60 25 60 30 90 30 100 30 100 30 110 30 90 30 100

Wilger

Information here is general guidance and not an endorsement or recommendation from Corteva AgriScience. Consult nozzle manufacturer or your advisor on nozzle and pressure selection. Minimum pressures are not recommended to achieve optimal coverage for weed control.

For PWM Systems: NOZZLE Designed for use with PWM systems NOZZLE Use with John Deere ExactApply ™ system ONLY

Coverage guide (factor of type, size and/or pressure range): Provides best balance of coverage and drift control Provides additional drift control by creating larger droplets No classification

Qualified Nozzles with Pressure Ranges (PSI)

Pressure Range (PSI)

Pressure Min Max

Nozzle Type Size

Manufacturer

110.04 110.06 110025 11003 11004 11005 11006

40 40 40 40 40 80 40 70 40 70 40 65 40 60

ABJ Agri

ABJ

AlbuZ

AVI

Greeneye Technology

25-03

20 80

GEE

11003 11004 11005 11006

15 35 15 35 15 35 15 35 20 45 20 40 20 50 20 60 20 60 20 60 30 40 30 45 30 65 30 75

025

03 04 05 06 08

TADF

11003 11004 11005 11006

TDXL

Greenleaf

11002-D 30 65 110025-D 30 70 11003-D 30 90 11004-D 30 90 11005-D 30 85 11006-D 30 100 11008-D 30 80

TDXL-D

110-04 110-05 110-06 110-08 110-10

20 90 20 85 20 40 20 80 20 80 20 35 20 20 20 45 20 55 20 60 20 45 20 55 20 50 20 55 20 75 20 30 20 80 20 70 20 65 20 40 30 80 30 80 30 100 30 100 30 100

03 04 05 06 08 10

PULSE GUARD SL- PWMG120

80-03 80-04 80-05 80-06 120-03 120-04 120-05 120-06 120-08 130-03 130-04 130-05 130-06 130-08

TRD

HyPro

ULD

ULDM

Coverage guide (factor of type, size and/or pressure range): Provides best balance of coverage and drift control Provides additional drift control by creating larger droplets No classification

For PWM Systems: NOZZLE Designed for use with PWM systems NOZZLE Use with John Deere ExactApply ™ system ONLY

Qualified Nozzles Enlist Duo ® herbicide

Pressure Range (PSI)

Pressure Min Max 20 80 20 80 20 80 20 80 20 80 20 80 30 75 30 65 20 35 20 70 20 65 20 50 20 40 30 80 30 80 30 100 30 100 30 100

Nozzle Type Size

Manufacturer

6003-R4 6004-R4 6005-R4 6006-R4 8004-R4 8005-R4 8006-R4 8008-R4

PSTSL

2003 2004 2005 2006 2008 3003 3004 3005 3006 3008 2003 2004 2005 2006 2008 2010

PSULD/ PSULDQ

John Deere

PSULDM/ PSULDMQ

20 35 20 20 20 45 20 55 20 60 20 45 20 80 20 80 30 70 30 70 30 75 30 80 30 80 30 80 30 65 30 75 30 75 30 75 30 80 30 80 30 80 30 80 30 80 20 25 20 35 20 40 20 40 20 55 20 55 20 45 15 25 15 45 15 45 15 30 15 60 15 60 15 60 15 70 15 75

PSLDM/ PSLDMQ

120-04 120-05 65-02E 65-025E 65-03E 65-04E 65-05E 65-06E 80-02 80-025 80-03 80-04 80-05 80-06 110-04 110-06

Lechler

110-08 110-03 110-04 110-05 110-06 110-08 110-10 110-15

TeeJet

AITTJ60

8003VK 8004VK 8005VK 110-03 110-04 110-05 110-06 110-08 110-10

AIXR

For PWM Systems: NOZZLE Designed for use with PWM systems NOZZLE Use with John Deere ExactApply ™ system ONLY

Coverage guide (factor of type, size and/or pressure range): Provides best balance of coverage and drift control Provides additional drift control by creating larger droplets No classification

Qualified Nozzles Enlist Duo ® herbicide

Pressure Range (PSI)

Pressure Min Max 20 90 20 90 20 90 20 85 20 90 20 90 20 85 20 75 20 75 20 75 20 75 15 65 15 70 15 65 15 85 15 65 15 55 15 55 15 55 15 65 15 60 15 55 15 50 15 50 30 50 30 50 30 70 30 70 30 60 30 100 30 100

Nozzle Type Size

Manufacturer

110-02 110-025 110-03 110-04 110-05 110-06 110-08 6503SS 6504SS 6505SS 6506SS 110-02 110-025 110-03 110-04 110-05 110-06 110-08 110-10 11003 11004 11005 11006 11008 110-03 110-04 110-05 110-06 110-08 110-10 110-125

APTJ

DGX

TeeJet

TTI

TTI60

40-08

20 70

80-04 80-05 80-06 80-08 80-10 80-125 110-04 110-05 110-06 110-08 110-10 110-125 80-06 80-08 80-10 80-125 110-03 110-04 110-05 110-06 110-08 110-10

25 35 25 45 25 70 25 70 25 70 25 70 25 35 25 35 25 60 25 60 25 50 25 70 25 25 25 55 25 60 25 60 30 90 30 100 30 100 30 100 30 90 30 100

Wilger

Coverage guide (factor of type, size and/or pressure range): Provides best balance of coverage and drift control Provides additional drift control by creating larger droplets No classification

For PWM Systems: NOZZLE Designed for use with PWM systems NOZZLE Use with John Deere ExactApply ™ system ONLY

Field Planning And Application Best Management Practices

Start With Field Planning Field planning is being aware of your surroundings in terms of compatible crops and susceptible crops. Good field planning is just good common sense; it’ll help maximize your success and the results of the Enlist ® weed control system. Prior to an application of an Enlist ® herbicide, carefully note the wind speed, wind direction and the crops and landscape that are adjacent to the field you plan to spray. Watch wind direction during an application — be aware of shifting winds during your application. DO NOT SPRAY Enlist ® herbicides when wind is blowing toward adjacent susceptible crops. Aerial application, including drone application, of Enlist herbicides is not authorized.

Avoid Downwind Susceptible Crops

An important part of stewardship with the Enlist weed control system is staying aware of your surroundings. It is especially important to protect susceptible crops and landscapes that have a high relative sensitivity to the 2,4-D choline in Enlist herbicides. Do not spray Enlist herbicides when the wind is blowing toward adjacent susceptible crops.

DO NOT SPRAY SUSCEPTIBLE CROPS

Cotton without Enlist ® trait

Fruiting vegetables

Grapes

Tomatoes

Scan the QR code to find the application guide for Enlist ® herbicides.

Cucurbits

Tobacco

Know What’s Around You Be sure to find out what else is planted near your Enlist ® field before you spray. That information is crucial to a safe application of an Enlist ® herbicide that allows you to access all the advantages of the Enlist ® weed control system. For example, one advantage of having a compatible crop adjacent to an Enlist ® field is you may apply an Enlist ® herbicide when the wind is blowing within labeled wind speed range toward that compatible crop.

Check Wind Speed And Direction

• Apply when wind speed is between 3 and 10 mph. Make sure to check with the state you are applying in as wind speed requirements may vary by state. Maximum wind speed on federal label of Enlist herbicides is 15 mph. • Always understand which crops and landscapes are downwind prior to making an application of an Enlist herbicide when deciding whether to spray or wait for better wind conditions. • Be aware of shifting winds during your application.

Compatible Crop Examples All soybeans Rice Corn Peanuts Wheat Sorghum Alfalfa

Controlling Spray Drift To Improve On-Target Application

Know And Follow Federal, State And Local Requirements

To minimize the potential for herbicide drift, consider these factors when deciding when and how to apply an Enlist ® herbicide: • Be mindful that wind direction and wind speed are within label parameters. • Use only labeled nozzles and pressure ranges. • Avoid temperature inversions. For more information on temperature inversions, see Page 26. • Confirm the method of application is consistent with the label. Always read and follow the product label as well as state and local requirements related to application of pesticides. Apply an Enlist herbicide only with properly calibrated ground application equipment. Remember: Do not apply an Enlist ® herbicide under circumstances where spray drift may occur to food, forage or other plantings that might be damaged or rendered unfit for sale, use or consumption. Do not allow contact of the herbicide with foliage, green stems or exposed nonwoody roots of crops or desirable plants, including trees and cotton without the Enlist ® trait, because severe injury or destruction may result. Even small amounts of spray drift that may not be visible may injure susceptible broadleaf plants. Before making an application, please refer to your state’s sensitive-crop registry (if available) to identify any commercial specialty or certified organic crops that may be located nearby. At the time of your application, the wind cannot be blowing toward adjacent commercially grown tomatoes and other fruiting vegetables (both in EPA Crop Group 8), cucurbits including watermelon, pumpkin, squash and cucumbers (all in EPA Crop Group 9).

Enlist Duo ® and Enlist One ® herbicides are not registered for sale or use in all states or counties. Contact your state pesticide regulatory agency to determine if a product is registered for sale or use in your area. When you apply an Enlist ® herbicide, you must follow all federal, state and local pesticide application requirements for Enlist Duo and/or Enlist One herbicides. Where states have more stringent regulations, they must be observed. Enlist Duo and Enlist One herbicides with Colex-D ® technology are the only herbicides containing 2,4-D that are authorized for preemergence and postemergence use on Enlist ® crops.* It is a federal offense to use any pesticide in a manner that results in an unauthorized “take” (e.g., kill or otherwise harm) of an endangered species or certain threatened species, under the Endangered Species Act Section 9. When using Enlist ® herbicides, you must follow the measures contained in the Endangered Species Protection Bulletin for the area you are applying the product. Before use of Enlist Duo and/or Enlist One herbicides, review the Restrictions section of the label to confirm that the county in which use is intended is not one where use is prohibited. In addition, obtain an Endangered Species bulletin for the intended use location no earlier than six months prior to the application and follow measures listed relevant to that location for the protection of endangered species. To obtain bulletins, consult the website www.epa.gov/espp , call 844-447-3813 or email espp@epa.gov . You must use the bulletin valid for the month in which you will apply the product. To report any ecological incidents, including mortality, injury or harm to nontarget plants or animals, call 855-ENLIST-1 .

* Enlist Duo and Enlist One have additional county restrictions in AL, GA, TN and TX. Contact your state pesticide regulatory agency to determine if a product is registered for sale or use in your area. Additional product-specific stewardship requirements for Enlist ® crops can be found at Enlist.com. Always read and follow label directions.

Field Planning Scenarios: Outside the Cotton Belt

Is It OK To Spray Enlist One ® Or Enlist Duo ® Herbicide?

Soybeans without the Enlist E3 ® Soybeans trait

Wind Direction 5 MPH

If an adjacent susceptible crop is downwind, DO NOT SPRAY an Enlist ® herbicide. Use glufosinate and/or glyphosate to stay ahead of weeds if necessary. Buffer distances do not protect downwind adjacent susceptible crops. The best scenario is to wait until wind is blowing directly away from the vineyard, tomatoes or other susceptible crop.

Vineyard or tomatoes

Enlist E3 ® Soybeans

Corn, wheat, alfalfa or sorghum

Soybeans without the Enlist E3 ® Soybeans trait

Wind Direction 8 MPH

It’s OK to spray when wind is blowing away from susceptible crops and toward soybeans without the Enlist E3 ® trait. Soybeans without the Enlist E3 trait are not a susceptible crop, meaning you can spray when the wind is blowing toward them with no field separation.

Vineyard or tomatoes

Enlist E3 ® Soybeans

Corn, wheat, alfalfa or sorghum

Soybeans without the Enlist E3 ® soybeans trait

Wind Direction 10 MPH

It’s OK to spray and there are no wind directional restrictions when wind is blowing toward an adjacent compatible crop, such as corn, wheat, alfalfa or sorghum. Watch for shifting wind during the application. If wind shifts toward the susceptible crop, stop spraying.

Vineyard or tomatoes

Enlist E3 ® Soybeans

Corn, wheat, alfalfa or sorghum

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