2025 Enlist Product Use Guide_Web

Using the Enlist ® weed control system to help prevent herbicide resistance development Glyphosate technology became the farm industry standard for weed control for many farmers. But using glyphosate as the primary, or only, herbicide site of action has resulted in glyphosate-resistant and hard- to-control weeds, including waterhemp, marestail, Palmer amaranth and giant ragweed. Repeated use of any single herbicide may reduce effectiveness for weed control. You can help manage weed resistance with an understanding of herbicide resistance and taking steps to prevent it. How weed resistance spreads For the first few years a herbicide is used, targeted weeds are controlled; however, after repeated application of the same herbicide — or herbicides with the same site of action — a few naturally occurring resistant weeds can remain in the field each year. As time goes on and resistant weeds thrive, the weed population starts to contain an even larger number of resistant weeds. Over time, the resistant weeds become the dominant population — rendering the herbicide no longer effective on that species. The Enlist ® weed control system provides an effective tool to use against these herbicide-resistant weeds, including glyphosate, ALS- and HPPD-resistant weeds. Use the Enlist ® system as part of an integrated weed management program to deliver the exceptional performance you need.

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Take advantage of different herbicide sites of action

It is a best practice to minimize selection for herbicide- resistant weed populations by proactively diversifying weed control strategies. A diversified weed management program may include the use of multiple herbicides with different sites of action and an overlapping weed control spectrum in combination with other practices, such as tillage operations and/or other cultural practices where appropriate. Using the labeled rate for herbicides and following directions for use is important to help prevent the onset of resistance.

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