THE CHALLENGES
❑ Single-gene or multi-gene conditions are studied in different ways ❑ Single-gene: Collect DNA from autistic individuals and family members ❑ Multi-gene: Genome-wide association studies (GWAS) with DNA from large numbers of cases and controls
❑ ASD presentation is variable
❑ Severe ASD can be part of a more complex genetic syndrome (e.g. Fragile X Syndrome)
❑ Initial studies revealed that we need thousands of participants for either one
Made with FlippingBook - professional solution for displaying marketing and sales documents online