GENES MUTATED IN ASD
ASD risk genes control: ▪ neuronal communication, synapse function and plasticity ▪ synaptic proteins, ion channels ▪ expression of hundreds of other genes ▪ epigenetic regulators, transcription factors ▪ neuronal responses to nutrients and growth factors ▪ signaling proteins
ASD risk genes are involved in fetal development They are often only partially changed in their function
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