Recent Advances in ASD Diagnosis
Early structural and functional brain imaging accurately predicts ASD diagnosis at 24 months! Nature. 2017 Feb 15;542(7641):348-351 Structural brain MRI at 6 (Blue) and 12 (Red) months accurately predicts (81%) which children will be diagnosed with ASD at 24 mo, especially social deficits. Early expansion of the cerebral cortex. In families with one child with autism, the next born sibling has a greater chance of autism – Established the Baby Siblings Study = higher risk of ASD
Functional connectivity MRI at 6 months accurately predicts which children will be diagnosed with ASD at 24 months. Sensitivity, 82%; Specificity, 100%. Red (-), Blue (+) connectivity
Sci Transl Med. 2017 Jun 7;9(393). pii: eaag2882.
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