The Role of Oxytocin in Social Behavior Select Neuronal Circuits?
Social Behavior in Voles - Monogamous vs Non-monogamous
The neuropeptide oxytocin (OT) regulates social behavior, including pair bonding and maternal-infant relations. OT acts via OT-Receptor and Arg-Vasopressin 1a-R.
Monogamous Prairie Vole
Non-Monogamous Montane Vole
Highly social Communal burrows Biparental child care 80% mate for life Separation-ultrasonic distress Not aggressive to intruders Isolated burrows No paternal child care Mate with multiple partners Separation-little distress Human clinical trials? Failed. But clinical subgroups? Yes DiCicco-Bloom, Rutgers Robert Wood Johnson Medical School
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