Vector-borne disease caused by protozoan parasites and transmitted through sandflies Leishmaniasis recap
At risk populations: HIV, immunocompromised, who lives in rural regions
Endemic in tropical and subtropical regions
Diagnosis:
Microscopic: biopsy Molecular: PCR Serological: antibodies against Leishmania Types:
Cutaneos: most common, cause skin sores. Treat with symptomatics Mucocutaneos: can involve nose, month or throat. Treat with amphotericin B Viscerous (kala-azar): most severe, can affect spleen, liver, bone marrow. Treat w amphotericin B or miltefosine
DDx: GPA (usually renal + lung involvement) Mycobacterium (possible) Mucormycosis (generally rapidly progressive and more severe)
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