Starter Kit | CRENESSITY® crinecerfont

The Impact of CRENESSITY for Liam

“Before starting CRENESSITY, my androgen levels such as 17-OHP were relatively high, but after starting CRENESSITY, they significantly lowered” -Liam

Liam has CAH, is taking CRENESSITY and is a paid partner of CRENESSITY

Before taking CRENESSITY

After 4 weeks of CRENESSITY

15% reduction

Androstenedione

72 ng/dL

61 ng/dL

90% reduction

17-OHP

692 ng/dL

71 ng/dL

Before taking CRENESSITY

After 24 weeks of CRENESSITY

30% reduction*

Hydrocortisone

25 mg/day

17.5 mg/day

17-OHP = 17-hydroxyprogesterone *As part of the CAHtalyst TM clinical study in adults

The Clinical Studies: A Quick Refresher. In clinical studies, CRENESSITY helped adults improve or maintain androgen control, allowing them to lower their steroid doses. In adults: After 4 weeks, androstenedione levels dropped by an average of 299 ng/dL with CRENESSITY and increased by 46 ng/dL in those taking placebo. After 24 weeks, steroid doses were reduced by an average of 27% with CRENESSITY and 10% for those taking placebo.

Please see Full Important Safety Information on last page and Patient Information.

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