MRF Endowment Case for Support

2 | ENDOWMENT CASE FUNDING

Despite the advances, melanoma treatments do not work for all patients. Recurrence and dormancy remain challenges for the scientific community. Ocular melanoma, the second most common type of melanoma, metastasizes to the liver 50% of the time and there are currently no FDA-approved treatments for this rare disease. A recent survey estimates that 20% of patients missed their annual skin exam due to COVID-19 resulting in an exponential increase in melanoma diagnoses in the years ahead. Melanoma is most common in men and their rate of diagnosis increases after age 50. Melanoma remains the leading cause of cancer death in women ages 25–30 and the second leading cause of cancer death in women ages 30–35. In ages 15–29, melanoma is the second most commonly diagnosed cancer. The incidence of young people under 30 developing melanoma is increasing faster than any other group, soaring in women by 50% since 1980.

2011

FDA approves the first targeted therapy for BRAF mutant metastatic melanoma.

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