J-LSMS | ACP Abstracts | 2025

chemotherapy which was complicated by suspected hemoperitoneum and rapid decline leading to intubation. Pathology confirmed high grade NEC with immunohistochemical stains positive for TTF-1, chromogranin, synaptophysin, and CD56, with near 100% KI-67 nuclear positivity. The patient quickly progressed to multi-organ system failure and expired shortly after transition to comfort focused care.

preceded the patient’s rapid clinical decline, it is crucial to recognize the morbidity related to the primary NEC and metastases. One such example is the obstructing lung mass resulting in complete collapse of the left upper lobe. This may have contributed to the patient’s respiratory decline leading to intubation and could further complicate weaning of mechanical ventilation. As such, early treatment with chemotherapy can potentially reduce risks and improve outcomes.

Discussion: While a procedural complication

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