Directing Biosynthesis VI - Book of abstracts

Oral presentations

C01

Identification and characterization of bifunctional fungal terpene synthases Jaclyn Winter University of Utah, USA Structure and function of a peptide crosslinking P450 from biarylitide biosynthesis Max Cryle Monash University, Australia Iterative peptide backbone N-methylation in borosin RiPP biosynthesis Michael Freeman University of Minnesota, USA

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Investigating the mechanisms of lanthipeptide biosynthesis using structural mass spectrometry

Christopher Thibodeaux McGill University, Canada

C05

Engineering of polyketide synthase leads to ‘low-fat’ stambomycins Li Su Max-Planck-Institute for Terrestrial Microbiology, Germany CRISPR-Cas9 in vivo editing enables rapid engineering of a complex antibiotic assembly line Wei Li Thong University of Manchester, UK Towards new more efficient and clinically relevant lincosamide antibiotics Zdenek Kamenik Institute of Microbiology Czech Acad Sci, Czech Republic Biosynthesis of the unusual carbon skeleton of nocuolin A Teresa Patricia Martins ICBAS, Portugal Enzymatic assembly of the salinosporamide gamma-lactam-beta-lactone anticancer warhead Katherine Bauman The Regents of the Univ. of Calif., USA

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