Research Fellowship: Year Three in Review Dr. Annie Shrestha was named the Dentsply Sirona Research
PUBLICATIONS ACCEPTED • Y. Zhu, D. Winer, C. Goh, A. Shrestha* . Injectable thermosensitive hydrogel to modulate tolerogenic dendritic cells under hyperglycemic condition. Accepted for publication in Biomaterials Science journal- The Royal Society of Chemistry (Impact factor- 7.59). PUBLICATIONS SUBMITTED • B. Yao, M. Ghaffari, A. Shrestha* . Porphyromonas gingivalis -stimulated Hyperglycemic Microenvironment Alters the Immunometabolism of Dendritic Cells. Under Review in the journal Immunology • Y. Zhu, C. Goh, A. Shrestha* . Tunable biomaterials for bone regeneration. Submitted to Frontiers in Dental Medicine, Special Issue. • M. Ghaffari, A. Kishen,
Fellow, in early 2020, for her work on the project, “Immune Dysbiosis in Diabetes and Apical Periodontitis – Role of Cell Microenvironment.” Following three years of mentored training and hard work, Dr. Shrestha provided her annual reporting requirements to showcase her progress. Dr. Shrestha has a research team of highly qualified personnel, including: • Binchen Yao (Jack), M.Sc. , research student (Graduated September 2022), thesis title- “Immunometabolism of Dendritic Cells in Porphyromonas gingivalis Stimulated Hyperglycemic Microenvironment”; awarded the Queen Elizabeth II Graduate Scholarship ($10,000; 2021) • Yi Zhu, Ph.D. , research student (Start date: January 2020), thesis title, “Develop and Characterize Novel Injectable Thermosensitive Scaffolds to Immunomodulate Dendritic Cells”; awarded the Queen Elizabeth II Graduate Scholarship ($15,000; 2020- 2021 and 2022-2023). He successfully completed his Ph.D. qualifying examination in January 2022. • Dr. Graziella Molska , part-time research technician helping with animal breeding and animal experimental work. • Dr. Maryam Ghaffari , part-time post-doctoral fellow helping with cell culture work and lab management. Part of the scholarship for the research students are covered by
Research Fellow
STUDENT PRESENTATIONS • Y. Zhu, C. Goh, A. Shrestha . Injectable thermosensitive hydrogel modulates tolerogenic dendritic cells under hyperglycemic condition. Canadian Biomaterials Society. 37th Annual Meeting. May 2022 (Poster) • B. Yao, A. Shrestha . microenvironment. IADR/APR General Session 2022 (Oral). • Y. Zhu, C. Goh, A. Shrestha . Modulating dendritic cells using thermosensitive hydrogel under hyperglycemia. IADR/APR General Session 2022 (Oral). The Foundation looks forward to even more outcomes from Dr. Shrestha. Immunometabolism of dendritic cells in Porphyromonas gingivalis - stimulated hyperglycemic She is deepening the of research in endodontics, and we look forward to the vast impact she will continue to make.
A. Shrestha* . Endocytic internalization mechanism of bioactive antibacterial nanoparticles by fibroblasts. Under Review in the journal Photochemistry and Photobiology.
INVITED/SUBMITTED PRESENTATIONS • Endodontic Treatment: Changing of the Guard?
International Association of Dental Research General Session, Bogota, Columbia. June 2023. • Regendo: What’s New? American Association of Endodontists Annual Meeting, Chicago, USA. May 2023. • Advances in Nano-Biomaterials for Treating Chronic Dental Infections. Nepalese Society of Periodontology and Oral Implantology. Kathmandu, Nepal. Feb 2023.
the Research Fellowship: • Graduate Student Thesis
Supervisory Committees: Dr. Emily Bishop, M.Sc. student, Endodontic Program (Year 2); Armin Mahdi Souzani, M.Sc. student (Year 2)
FOCUS 2023
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