QUARTERLY BEAT / OCTOBER 2025
A metacarpal wound treated with amnion, healing well 7 weeks later (Photos courtesy of Dr. Holly Roessner, DACVS-LA)
REFERENCES
1. Bischofberger AS, Tsang AS, Horadagoda N, et al. Effect of activated protein C in second intention healing of equine distal limb wounds: a preliminary study. Aust Vet J. 2015;93:361–6. 2. Bischofberger AS, Dart CM, Perkins NR, et al. The effect of short- and long-term treatment with manuka honey on second intention healing of contaminated and noncontaminated wounds on the distal aspect of the forelimbs in horses. Vet Surg. 2013;42:154–60. 3. De Clercq E, Den Hondt S, De Baere C, et al. Effects of various wound dressings on microbial growth in perfused equine musculocutaneous flaps. Am J Vet Res. 2021;82:189–197. 4. Chevalier JM, Pearson GB. Amorphous silicate technology produces good results in equine distal limb wound healing. J Am Vet Med Assoc. 2023;261(6):1-5. 5. Monteiro SO, Lepage OM, Theoret CL. Effects of platelet-rich plasma on the repair of wounds on the distal aspect of the forelimb in horses. Am J Vet Res. 2009;70(2):277-82. 6. McCoy AM. How to prepare ad store equine amnion for use as a biological wound dressing. AAEP Proceedings 2017. https://www.cabidigitallibrary.org/doi/ pdf/10.5555/20193333603 7. Fowler AW, Gilbertie JM, Watson VE, et al. Effects of acellular equine amniotic allografts on the healing of experimentally induced full thickness distal limb wounds in horses. Vet Surg. 2019; 48(8):1416-1428.
In summary, there are many topical products available. Some should never be used (nitrofurazone), some should be used with caution in certain scenarios only (steroids), and others can be used based on practitioner experience and preference. The topicals presented here have some, though still limited, evidence- based support. Frequent evaluation of wound healing to ensure it is progressing as expected is recommended. Repeat debridement should be performed if infection or exuberant granulation tissue occurs, and underlying metabolic disorders affecting the immune system should be diagnosed and treated if wound healing is still delayed.
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