QUARTERLY BEAT
APRIL 2026
Diagnostic Dilemma – Support vs. Confirmation Diagnosing FIP can be frustrating, especially in dry (non-effusive) cases where you don’t have biopsy results or the benefit of an accessible and diagnostically useful effusion sample. The clinical signs of FIP are often nonspecific and many readily available tests in practice provide diagnostic support rather than confirmation of FIP. The gold standard for confirmation remains immunohistochemistry (IHC) demonstrating FIP viral antigen
within macrophages, typically performed on tissue samples obtained via laparoscopy, laparotomy, or post-mortem examination. If ocular involvement
is present, aqueous humor can also be submitted for IHC. In
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