Synthesis of cyclobutanes by contraction of pyrrolidines Andrey Antonchick Nottingham Trent University, UK A contractive synthesis of multisubstituted cyclobutanes containing several stereocenters has been developed from readily available pyrrolidines using iodonitrene chemistry. The stereospecific synthesis of cyclobutanes is based on a radical pathway and mediated by the nitrogen extrusion process. Unprecedented cyclobutanes have been successfully prepared. The developed method was used in the formal synthesis of the natural product piperarborenine B.[1] References 1. J. Am. Chem. Soc. 2021, 143, 45, 18864–18870
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