RSC Tokyo International Conference 2023
Paper-based Optical Chemosensor Arrays
Tsuyoshi MINAMI Institute of Industrial Science, The University of Tokyo
Biographical Sketch Tsuyoshi Minami obtained his Ph.D. from Tokyo Metropolitan University in 2011. During his Ph.D. research, he worked at University of Bath as a collaborative researcher. Between 2011 and 2013, he worked as a Postdoctoral Research Associate at Bowling Green State University and was appointed as a Research Assistant Professor in 2013. In 2014, he proceeded to Yamagata University as an Assistant Professor. Thereafter, he was appointed as a Lecturer at the University of Tokyo in 2016, and Associate Professor since 2019. His research interests are supramolecular analytical chemistry, self-assembled materials, nanoparticles, and organic transistors for bio/chemical sensing applications. Abstract Chemosensors are promising candidates to visualize molecular recognition information through colorimetric or fluorescence responses. The concept of chemosensor arrays is inspired by molecular recognition manners in the mammalian olfactory system, which shows an ideal cross-reactive response for the discrimination of abundant odorant molecules. 1 In the mammalian olfactory system, a small number of receptors can simultaneously detect thousands of odorant molecules owing to their cross-reactivity, achieving recognition of flavors based on pattern recognition. Inspired by the biological sensing system, the author has focused on molecular self-assemblies for the development of chemosensor arrays. 1 The self-assembled chemosensors can offer various optical responses by analyte recognition, resulting in fingerprint-like response patterns for multi-analyte detection. With a methodology based on supramolecular chemistry, the author has successfully fabricated the self-assembled chemosensor arrays with a small number of building blocks to discriminate various analytes toward diagnosis, environmental assessment, and food analysis. As further attempts, the author has proposed printed solid-state chemosensor devices made of paper for on-site analysis. 2 In contrast to conventional chemosensing using spectrophotometers, optical responses on paper-based chemosensor array devices (PCSAD) can be recorded using portable digital recorders, followed by imaging analysis (Figure 1). 2,3 The obtained digital images are subsequently data-processed by pattern recognition techniques, obtaining qualitative and quantitative sensing results.
Figure 1. Illustrated conceptual figure of paper-based chemosensor array devices for pattern recognition.
RSC Tokyo International Conference, Makuhari Messe, Chiba, Japan, September 7-8, 2023.
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