RSC Tokyo International Conference 2023

RSC Tokyo International Conference 2023

Wearable sweat glucose sensor designed as a waist strap connected with a smartphone readout

Nadtinan Promphet a , Chusak Thanawattano b , Thidarut Laochai a , Panlop Lormaneenopparat a , Pranee Rattanawaleedirojn a,c , Pranut Potiyaraj a,c , Nadnudda Rodthongkum a,c * a Metallurgy and Materials Science Research Institute, Chulalongkorn University, Soi Chula 12, Phayathai Road, Pathumwan, Bangkok 10330, Thailand b National Science and Technology Development Agency, Pathumthani 12120, Thailand c Center of Excellence in Responsive Wearable Materials, Chulalongkorn University, Soi Chula 12, Phayathai Road, Pathumwan, Bangkok, 10330, Thailand

Biographical Sketch

Nadnudda Rodthongkum, Ph.D. ( h -index: 29, Citations: 2,752) is a research professor and deputy director at Metallurgy and Materials Science Research Institute, Chulalongkorn University. She obtained her Ph.D. in chemistry from University of Massachusetts, Amherst, USA. Also, she worked at Abbott Bioresearch Center, Wocester, MA, USA for 1 year in bioanalytical research group. Her current research focus is design and synthesis of new materials for enhanced analytical performances of chemical sensor and laser desorption ionization mass spectrometric (LDI-MS) detection.

Abstract

Diabetes is a chronic, non-communicable disease affecting people of all ages leading to increased mortality rate worldwide and glucose is a key biomarker for both type 1 and type 2 diabetes 1 . Nowadays, glucose level is

commonly measured by blood drawing requiring a painful sample collection. Alternatively, glucose can be detected in other biofluids such as tears, saliva and sweat 2 . Herein, the wearable electrochemical sensor based on a flexible electrode for real-time detection of sweat glucose is fabricated. The flexible working electrode surface is chemically modified by nanomaterial and glucose oxidase to enhance the overall sensor performances and specificity towards sweat

Figure 1. Illustration of waist strap connected with smart phone readout for sweat glucose sensor.

glucose detection. The modified electrode surfaces are systematically characterized by scanning electron microscopy (SEM), atomic force microscopy (AFM) and fourier transform raman spectroscopy (FTIR). Amperometry is carried out on hydrogen peroxide (H 2 O 2 ) detection for electrochemical characterization of the modified electrodes. A waist strap circuit and a smartphone readout of this sensor are customized designed to be directly connected with a bluetooth for real-time measurement of sweat glucose excreted from the wearer sweat on the

RSC Tokyo International Conference, Makuhari Messe, Chiba, Japan, September 7-8, 2023.

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