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Pillar # 4: Sleep, mood and cognition Cognitive decline, poor sleep, and emotional instability are not inevitable. Many of these issues are linked to declining mitochondrial function, chronic inflammation and poor blood sugar control. Nicotinamide riboside supports brain energy metabolism and the production of brain-derived neurotrophic factor (BDNF), a key molecule involved in memory and neuroplasticity. Berberine stabilises blood sugar, which reduces the glycaemic spikes that can impair mood and cognition. Resveratrol further supports neuroprotection through its antioxidant effects.
Pillar # 5: Hormonal balance Hormones orchestrate every action and outcome in the body, from metabolism to mood, and sleep to libido. With age, hormonal shifts, especially in oestrogen, testosterone and cortisol, can leave us feeling flat, foggy or out of balance. Metabolic health is again the key. Berberine regulates insulin and cortisol, two hormones that directly influence the broader
Top tip: Limit screen time before bed, eat your last meal early in the evening, and build stress resilience with mindfulness or breathing techniques. Nutrients found in NAD+ Booster, Cellular Longevity, and Berberine Complex can help to protect brain function as part of a whole-body strategy.
hormonal network. Nicotinamide riboside supports adrenal and mitochondrial function, helping your body better adapt to stress. Quercetin may also reduce the inflammation that interferes with hormonal signalling. Top tip: Reduce alcohol, support liver function (crucial for hormone clearance), and focus on consistent sleep and stress management. For deeper support, targeted ingredients like those found in Berberine Complex and NAD+ Booster can modulate the metabolic environment where hormones operate. Danny Urbinder is a naturopath and educator with over 30 years of experience in the health and wellness industry, including leadership roles in practitioner education. He co-developed a successful genetic testing service and has a strong foundation in nutritional biochemistry and functional pathology. Danny continues to bridge
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ISSUE 74 • 2025
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