Scientific Data by Clinical Problems
Gingivitis/Periodontitis
In fact, healthy periodontal tissues can be promoted by supra- and subgingival biofilm homeostasis. When oral microbiota becomes dysbiotic, periodontal pathogens evoke inflammation in the gingiva ‘Gingivitis’, and then tissue destruction ‘Periodontitis’. New treatment modalities, such as blue®m oxygen therapy, have emerged to maintaining healthy oral flora ‘biofilm homeostasis’ and treating existing disease. In a microbiological study, Professor Tatiana Deliberador and co-workers (Brazil) proved the inhibition effect of blue®m oxygen therapy at higher concentration on Porphyromonas gingivalis, as the keystone pathogen of periodontitis [1]. Also, Dr R Niveda and Dr G Kaarthikeyan (India) confirmed the
effect of blue®m oxygen therapy in the treatment of periodontitis [2, 3]. For gingivitis, Professor Tatiana Deliberador (Brazil) was also co-authored a randomized controlled clinical trial to study the long-term (up to 18-weeks) antigingivitis efficacies of commercially available dentifrices [4]. The study results demonstrated that blue®m oxygen therapy has remarkable effect in controlling supragingival biofilm, as the primary cause of gingival inflammation. Clinically, Dr Irfan Abas (The Netherlands) and more dental specialists have presented several cases showing the significant impact of blue®m oxygen therapy on gingivitis and periodontitis [5,6].
Wound Healing
Oral wounds can involve oral soft tissue and/or hard tissue. In fact, oxygen plays an important role in wound healing, as it is vital for energy production and protein synthesis, cellular proliferation, angiogenesis, and the restoration of tissue functions. A review by Professor Wei Cheong Ngeow (Malaysia) and co- authors reappraises the current knowledge on the application of topical oxygen technology (blue®m) to promote oxygenation and angiogenesis in wound healing [15]. Recently, Dr. Marcos Motta, Professor Tatiana Deliberador, Dr. Camila Vianna, and Professor Geninho Thomé (Brazil) have published a full chapter on many clinical options to achieve predictable soft and bone tissue repair or regeneration. The use of
blue®m oxygen therapy shows always a promising clinical outcomes [16]. Dr. Juliana Habib (Syria) proposed that the use of blue®m as dressing on gingival healing and pain after surgical depigmentation [17].
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