New Perspectives

who doesn’t feel pain the Woman WHAT THE FUTURE HOLDS.... As for people with CIP, Woods says he doesn't know if treatment using naloxone is an option. Long-term use of naloxone could have side effects. What Woods can say, denitively, is that the mice in the experiment felt as little pain as mice who did not have the Nav1.7 channel naturally. Woods, his team, and the rest of the eld are working to ll in the research gaps to start answering these questions for humans. “We hope to see our approach tested in human trials by 2017 and we can then start looking into drug combinations to help the millions of chronic pain patients around the world,” Woods says.

Could help in making better painkillers.

Imperial College London professor Kenji Okuse reacted to Wood’s ndings to the New Scientist, saying that the research will provide more information to doctors about pain.

We hope to see our

“Opioids and Nav1.7 blockers could provide much stronger analgesics, but they will not necessarily be better for patients,” Okuse says. “If we take the combination therapy route, people would have to take opioids throughout the lifetime, which is not a welcome thing.”

approach tested in human trials by 2017 and we can then start looking

into drug combinations to help the millions of chronic pain patients around the world. — John Wood, University College London

Wolfson Institute for Biomedical Research researcher

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