Animal Health Product Catalogue New Zealand

By Boehringer Ingelheim Animal Health NZ

When animals are healthy, humans are healthier too.

Boehringer Ingelheim Animal Health has the privilege and the responsibility of being one of the largest animal health businesses in the world. We will use that scale and our combined resources to help make the industry even better at improving animal health. We are passionate about animal health, and we recognise the critical importance of serving animal health needs, with a special focus on preventative medicine. We know that when animals are healthy, humans are healthier, too. Farmers can count on Boehringer Ingelheim to support them in raising and caring for animals in a healthy, sustainable and financially viable way, because we want to build confidence with consumers about the food they eat. Pet owners have lifelong emotional connections with their pets and consider them to be family members; that’s why we are focused on helping pets live longer and healthier lives. With pioneering and market leading brands such as BIONIC, EPRINEX, ECLIPSE, MATRIX, NEXGARD SPECTRA, METACAM, PREVICOX and PRASCEND we will work to meet and exceed the needs of pet owners, veterinarians, producers, the communities we work in and the industry at large.

CONTENTS

ANTHELMINTICS

5 5

Triple Combinations

Injections

Capsules

MINERALS

8 9

THERAPEUTICS

PARASITES

10 10

Internal Parasite Life Cycles

Faecal Egg Count Reduction Test

DOSING GUIDE

ANTHELMINTICS

16 16

Triple Combinations

Double Combinations

Single Actives

MINERALS

19 19

Injections

Capsules

THERAPEUTICS

19 22 22

PARASITES

Internal & External Parasite Life Cycles

DOSING GUIDE

THERAPEUTICS

26 27

SEDATIVES

PARASITICIDES

29 31 32 32

Deworming Protocols

THERAPEUTICS

Inflammation & Pain

Therapeutics

Antibiotics

futureproducers.co.nz

SHEEP PRODUCTS

ANTHELMINTICS

Triple Combinations Injections Capsules

MINERALS THERAPEUTICS PARASITES Internal & External Parasite Life Cycles Faecal Egg Count Reduction Test

DOSING GUIDE

SHEEP

Anthelmintics

Triple combination drenches contain three drugs that act in different ways to kill internal roundworms. Triple combination products have been shown to significantly slow the development of drench resistance. The sooner combination drenches are used the more effective they will be at preventing resistance development, particularly when used with management strategies that help to preserve sensitive parasites. Veterinarians are best placed to advise on resistance prevention.

Triple Combinations

MATRIX® Hi-Mineral

Actives: Abamectin, Levamisole, Oxfendazole Pack size: 1 L, 5 L, 10 L & 20 L

Active Minerals Dose rate WHP

Controls Admin

5KG 1

14 MEAT

35 MILK

Mineralised.

Applicators

Sheep Oral Gun (15 mL) Gun size: 15 mL Code: 147286

For Matrix Hi-Mineral.

Boehringer Ingelheim Animal Health New Zealand Ltd Product Guide 2022 5

SHEEP

Anthelmintics

Long-acting single active moxidectin injections should only be used in specific circumstances. Moxidectin provides excellent control of Haemonchus contortus (Barber’s Pole). Veterinarians should be involved in long-acting injection treatment decision making, as advice on management techniques to reduce the threat of parasite resistance developing, such as refugia and drench check testing, is paramount.

Injections

EXODUS® LAI

Active: Moxidectin Pack size: 500 mL

Active Dose rate WHP

Admin

Protection against sensitive Teladorsagia (Ostertagia) circumcincta for 112 days,

20KG 1

91 MEAT

180 MILK

s/c

Haemonchus contortus for 91 days and Trichostrongylus colubriformis for 42 days.

EXODUS® 1% Injection

Active: Moxidectin Pack size: 500 mL

Active Dose rate WHP

Admin Other*

Protection against sensitive Teladorsagia (Ostertagia) circumcincta and Haemonchus contortus for at least 35 days.

50KG 1

28 MEAT

35 MILK

s/c

*Displayed dose rate, withholding periods, indications and administration route are for this section’s species only. Please see product label for other species details.

Applicators

Sheep Injector (5 mL)

Gun size: 5 mL Code: 127140

For EXODUS LAI Injection.

Sheep Injector (2 mL)

Gun size: 2 mL Code: 147318

For EXODUS 1% Injection.

SHEEP

Anthelmintics – Controlled Release

Capsules provide long periods of parasite control compared to oral drenches. When used appropriately, capsules are extremely effective at controlling the impact of parasites on stock. Veterinarians should be involved in capsule treatment decision making, as advice on management techniques to reduce the threat of parasite resistance developing, such as refugia and drench check testing, is paramount. Capsules should be administered carefully by an experienced person with the applicator gun.

Capsules

Actives: Abamectin, Albendazole Dose rate: 40-80 kg (1 capsule), 80+ kg (2 capsules) Pack size: 5 x 100 capsules 100 day double combination continuous payout. The ultimate pre-lamb treatment. Cobalt and selenium pass through the ewe’s milk into her growing lambs. Adult sheep only.

BIONIC® Plus

Active Minerals

WHP

Controls Admin

126 MEAT

126 MILK

Applicators

Sheep Capsule Gun (Large) Gun size: 40-80 kg Code: 146573

For BIONIC Plus.

Boehringer Ingelheim Animal Health New Zealand Ltd Product Guide 2022 7 7 Boehringer Ingelheim Animal Health New Zealand Ltd Product Guide 2022

SHEEP

Minerals

Injections

COPAJECT

Active: Calcium copper edetate Dose rate: 1 mL Pack size: 200 mL

Minerals

WHP

Admin Others*

0 MEAT

0 MILK

For the treatment and prevention of copper deficiency in cattle, sheep and deer.

s/c

MARKS-MIN ZMS with B 12

Actives: Zinc, Manganese, Selenium, Vitamin B 12 Dose rate: 1.5 mL/50 kg Pack size: 500 mL

Minerals

WHP

Admin Other*

0 MEAT

0 MILK

B 12

Zn Mn

s/c

Trace minerals to support growth, reproduction and immune defence, with the energy from vitamin B 12 for optimum health and performace. DO NOT retreat animals for 8 weeks after last treatment.

*Displayed dose rate, withholding periods, indications and administration route are for this section’s species only. Please see product label for other species details.

Applicators

MARKS-MIN Injectors

Gun size: 5 mL & 12 mL Code: 162045, 162188

For MARKS-MIN products.

COPAJECT Injector (5 mL)

Gun size: 5 mL Code: 156287

For COPAJECT product.

8 *Displayed dose rate, withholding periods, indications and administration route are for this section’s species only. Please see product label for other species details.

SHEEP

Therapeutics

BIVATOP® 200

Active: Oxytetracycline Dose rate: 1 mL /10 kg Pack size: 100 mL & 250 mL

Dose rate

WHP

Admin

Others*

10KG 1

35 MEAT

35 MILK

Oxytetracycline is a green light broad spectrum antibiotic with bacteriostatic activity. Treats a wide range of common respiratory and local infections associated with oxytetracyline-sensitive organisms.

s/c i/m

MAMYZIN®

Active: Penethamate hydriodide Dose rate: 2.5 g/day for 1-5 days Pack size: 5 g & 10 g

WHP

Admin

Others*

7 MEAT

35 MILK

Green light antibiotic for the treatment of infections by Gram-positive bacteria that cause mastitis, footrot, respiratory and uterine infections.

s/c i/m

METACAM® 20 Solution for Injection

Active: Meloxicam 20 mg/mL Dose rate: 1 mL /20 kg Pack size: 50 mL, 100 mL & 250 mL

Dose rate WHP

Admin

Others*

Non-steroidal anti-inflammatory for use in sheep and lambs over 2 weeks of age for the alleviation of pain and inflammation. Administer high on the neck behind the ear under the skin.

20KG 1

11 MEAT

s/c

*Displayed dose rate, withholding periods, indications and administration route are for this section’s species only. Please see product label for other species details.

Boehringer Ingelheim Animal Health New Zealand Ltd Product Guide 2022 9

I T E U P T

A I L H

O S T

LIVER FLUKE Fasciola hepatica

BARBER’S POLE WORM Haemonchus contortus

BROWN STOMACH WORM Teladorsagia/Ostertagia circumcincta

TIPS: This parasite can live in sheep, cattle and deer. TREATMENT: Sheep are particularly sensitive to immature fluke migrating through their livers, so they need to be treated with a product that kills immature flukes.

THE BLOOD SUCKING PARASITE. PERFECT CONDITIONS: Usually seen seasonally as it needs warm ambient temperatures for its larvae on the pasture to survive. One adult parasite can produce up to a whopping 15,000 eggs per day. TIPS: During the risk period for BPW, a product that has persistent activity is advised, as the ‘teenaged’ worms suck blood before they become adults at 3 weeks post-ingestion. BPW has the ability to inhibit its own development inside the sheep and re-emerge during more favourable conditions i.e. the following spring. RESISTANCE: Low levels of resistance to the BZs only.

PERFECT CONDITIONS: Larvae survive freezing on pasture, and can ‘hibernate’ in stomach wall. A major worm of ewes around lambing, and of lambs during the spring and early summer. SIGNS: Reduces appetite, hampering growth in lambs and milk production in ewes. RESISTANCE: Moderate to high levels of resistance seen to all single active drenches. Moderate levels of resistance to combination drenches but this has been increasing over the past few years.

BLACK SCOUR WORM Trichostrongylus spp.

THIN-NECKED WORM Nematodirus spp.

TAPEWORM Moniezia spp.

PERFECT CONDITIONS: Larvae survive well in cooler conditions and so disease is often seen in autumn. SIGNS: Reduces growth in lambs and milk production in ewes. RESISTANCE: Moderate levels of resistance seen to Lev and BZ. Increasing levels of resistance to abamectin, moxidectin, and combination drenches. Triple combination and novel drench resistance becoming more common.

TIPS: By itself it rarely causes reduction in growth and productivity. Gastrointestinal parasites causing diarrhoea can predispose lambs to flystrike. TREATMENT: Albendazole (BZ) is known to have moderate efficacy against tapeworm but praziquantel is the drug that specifically targets tapeworms. SIGNS: Tapeworm is the only gut worm that you can actually see in the faeces of animals.

DISTRIBUTION: Two different species ( N. filicollis and N. spathiger ) are usually present on most farms. PERFECT CONDITIONS: N. filicollis requires a period of chilling in order to be able to hatch, meaning that eggs produced one season don’t hatch until the following spring. RESISTANCE: There are high levels of resistance to the BZs, particularly in N. spathiger . There are moderate levels of resistance to levamisole and BZ/Lev combinations. MLs, ML/Lev and triple combinations remain highly effective.

Boehringer Ingelheim Animal Health New Zealand Ltd Product Guide 2022 11

SHEEP

FECRTs and larval counts look to give a snapshot in time of the levels of resistance of different parasite species to the different drench classes and combinations of these on a property. Each drench class and combination is tested in a minimum of 10 lambs (30 lambs/group provide much better accuracy. The more that can be included in each group the better). Depending on the number of drench classes and combinations that require testing, you will usually need at least between 60 and 100 lambs that have not been drenched within 4-6 weeks before you start the test. The test involves taking baseline faecal samples on the day of the drench and taking faecal samples 10-14 days later. Faecal Egg Count Reduction Test (FECRT) and Larval Count

WHAT YOU WILL NEED

Day 0: Getting baseline results and drenching

10 mL Syringes (for dosing)

Identification method; ear tags or marker

INDIVIDUAL FAECAL SAMPLES (x 20) Take individual faecal samples from 20 randomly selected lambs from the whole mob of lambs. This can be 3 or 4 lambs from each drench group depending on the number of groups you have. Don’t forget to use disinfectant-free lube. • Identify the samples with the lamb’s number if possible. • Lab tests to request: 20 x Individual Faecal Samples for faecal egg count (FEC)

Plastic bags/pottles for collecting faeces; Day 0 x 20, Day 10-14 x 60-300

Marker pen

Weigh scales

1 x Pooled Quantitative Larval Culture (using all 20 samples)

RECOMMENDED DRENCH CHECK GROUPS

DRENCHING • Randomly allocate lambs into a drench group, a minimum of 10 lambs per group. • Weigh each lamb and dose using a syringe according to the instructions. • Identify each lamb by ear tag or marker so that they can be identified in 10-14 days’ time.

1. Control Group – no treatment 2. Abamectin 3. Oxfendazole 4. Levamisole 5. Abamectin/Benzimidazole 6. Abamectin/Oxfendazole/Levamisole

Day 10-14: Faecal sample collection day

OTHER GROUPS THAT CAN BE ADDED TO TEST

INDIVIDUAL FAECAL SAMPLES Collect individual faecal samples from each lamb and identify each one with the lamb’s number - and/or the marker colour i.e. must identify to drench group.

7. Moxidectin 8. Oxfendazole/Levamisole 9. Derquantel/Abamectin 10. Monepantel/Abamectin

• Lab tests to request: 60-100 minimum individual faecal samples

1 x Quantitative Larval Culture per group

SHEEP

FECRTs and Larval Count

Calculating the results

Helpful Hints & Tips

F AECAL EGG COUNTS FECs do not differentiate between different parasite species apart from Nematodirus . Eggs are allowed to hatch in the laboratory into larvae and identified to parasite species under a microscope. The FECRT may show that some parasites survived the drench but the larval culture is necessary to show which parasite species these are. • Sum the individual FECs from each group at Day 10-14 and divide by the number of lambs in the group to get a mean FEC for each group. • Use the formula below to calculate the % FEC reduction for each group.

• Weaning time is a good time to do a FECRT as commonly lambs have not been previously drenched. As it is early in the season, it is a good idea to do a couple of FECs before weaning to check that there are enough eggs in the lambs’ faeces to start the FECRT. Ideally you’d have an average of 500-700 epg with all lambs positive, but at least 300 epg is necessary (otherwise it’s unlikely to get good numbers of all worm species). • If the FECRT is done when the worm challenge is high and a control group is an animal welfare concern then this group should be removed from the test. The control group is a good source of information for the laboratory parasitologist when interpreting the results but it is not absolutely necessary. You can use the Day 0 results instead of the control at Day 10 in the calculations. • Make a call about courier reliability when planning the test. Doing Day 14 is easier so that samples can be sent in the week. Going a few days over day 14 is fine, you just may find some eggs in the levamisole group due to this drug not commonly killing immature worms. • The pasture that these lambs have previously grazed on is what is assessed. Don’t make assumptions about different parts of the property that lambs do not regularly graze and were not grazing on before Day 0. In other words, manage the group to sample the area of the farm you are interested in – lambing paddocks are a good representation usually. Keep them away from the quarantine paddock by the yards! • Day 0 can be made more efficient (and therefore the test more cost-effective) by the farmer pre-weighing and organizing the groups before the vet arrives. The same applies to Day 10-14. BUT they can’t yard the animals too early or it becomes harder to get faecal samples.

= Drench Group Mean FEC Day 10-14 Control Group Mean FEC Day 10-14

% FEC Reduction

x 100

PARASITE SPECIES LARVAL COUNTS A total larval count for each group is given with the % contribution of each parasite species to this total number.

• To get a parasite species larval count at day 10-14 for each group follow the calculation below.

Parasite Species % Composition

x Group Total Larval Count

100

• Then use the formula below to calculate the % larval count reduction for each parasite species in each group.

% Parasite Species Larval Count Reduction

= Drench Group Larval Count Day 10-14 Control Group Larval Count Day 10-14

x 100

Drench Check

A drench check is a quick way of looking at whether a certain drench is killing adequate numbers of parasites on a property. Follow all the instructions as per the FECRT but with only one group. A control group can be added for a more robust test. Check all drenching equipment is working well if not using a syringe to drench i.e. calibrate drench guns at the beginning and end of drenching at the least. If no control group is included substitute the Day 0 results for the Day 10-14 control into the calculations. Ensure drenches used for drench checks are relatively fresh, and well shaken. The quality of information out of a drench check depends on how well it is done!

Boehringer Ingelheim Animal Health New Zealand Ltd Product Guide 2022 13

SHEEP

Dosing Guide

PACK SIZE

DOSE RATE

25 kg 30 kg 35 kg 40 kg 50 kg 60 kg 70 kg 80 kg

500 mL

1 mL/20 kg

400

333

285

250

200

166

142

125

500 mL

1 mL/50 kg

1000

833

714

625

500

416

357

312

1 L

1 mL/5 kg

200

166

142

125

100

5 L

1 mL/5 kg

1000

833

714

625

500

416

357

312

10 L

1 mL/5 kg

2000

1666

1428

1250

1000

833

714

625

20 L

1 mL/5 kg

4000

3333

2857

2500

2000

1666

1428

1250

50 L

1 mL/5 kg

10000 8333

7142

6250

5000

4166

3571

3125

Number of sheep treated on pack size and dose rate.

Ensure young stock become future high producers through improved health, growth and energy at: futureproducers.co.nz

14 *Displayed dose rate, withholding periods, indications and administration route are for this section’s species only. Please see product label for other species details.

futureproducers.co.nz

CATTLE PRODUCTS

ANTHELMINTICS

Triple Combinations Double Combinations Single Actives

MINERALS Injections Capsules

THERAPEUTICS PARASITES Internal & External Parasite Life Cycles

DOSING GUIDE

CATTLE

Anthelmintics

Triple combination drenches contain three drugs that act in different ways to kill internal roundworms and lungworm. Triple combination products have been shown to significantly slow the development of drench resistance. The sooner combination drenches are used the more effective they will be at preventing resistance development, particularly when used with management strategies that help to preserve sensitive parasites. Veterinarians are best placed to advise on resistance prevention.

Triple Combinations

MATRIX® C Hi-Mineral

Actives: Abamectin, Levamisole, Oxfendazole Pack size: 5 L, 10 L & 20 L

Active Minerals Dose rate WHP

Controls Admin

20KG 1

14 MEAT

35 MILK

Mineralised. Ideal quarantine drench.

Applicators

Cattle Oral Gun (30 mL) Gun size: 30 mL Code: 149868 Floating Hook Code: 147314

For MATRIX C Hi-Mineral.

CATTLE

Anthelmintics

Double combination drenches contain two drugs that act in different ways to kill roundworms and lungworm. Other drugs may be added to control other parasites such as liver fluke or tapeworm. It doesn’t matter which method of delivery is chosen, as all have been shown to be effective, as long as the right product is chosen for the right situation and instructions for application on the label are followed. To ensure that these drenches are effective for years to come, it is important to use them appropriately and with particular regard to ensuring that sensitive parasites to these drugs remain on the property. Veterinarians are best placed to advise on sustainable use of drenches.

Double Combinations

ECLIPSE® Pour-On

Actives: Abamectin, Levamisole Pack size: 2.5 L, 5L & 5.5 L

Active Dose rate WHP Rain Fast Controls Admin

World’s first double combination pour-on. Ideal for use in R1 and R2 stock where Cooperia and Ostertagia control is necessary.

20KG 1

35 MEAT

35 MILK

ECLIPSE® E Injection

Actives: Eprinomectin, Levamisole Pack size: 500 mL World’s first double combination injection. Ideal for use in R1 and R2 stock where Cooperia and Ostertagia control is necessary. Prior to use store in the fridge to maintain excellent efficacy and quality, right up to the expiry date.

Active Dose rate WHP

Safety Controls Admin

35KG 1

21 MEAT

35 MILK

s/c

ECLIPSE® E Injection with B 12 & Se

Actives: Eprinomectin, Levamisole Pack size: 500 mL & 3 L (6 x 500 mL) Vitamin B 12 and Se added to ECLIPSE E injection to support

Active Minerals Dose rate WHP

Safety Controls Admin

35KG 1

21 MEAT

35 MILK

B12

s/c

growth, immunity and reproduction. Aids in the treatment and prevention of selenium and vitamin B 12 (cobalt) deficiency.

Prior to use store in the fridge to maintain excellent efficacy and quality, right up to the expiry date.

Applicators

Cattle Pour-On Gun (30 mL) Gun size: 30 mL Code: 126769 For ECLIPSE Pour-On.

ECLIPSE E Injector (12 mL) Gun size: 12 mL Code: 149872 For ECLIPSE E Injections.

Boehringer Ingelheim Animal Health New Zealand Ltd Product Guide 2022 17

CATTLE

Anthelmintics

In adult cattle Ostertagia is the only roundworm that reduces productivity. This means that single active products can be used that target Ostertagia . These drugs may also be effective against lungworm and lice. Liver fluke affects adult cattle and drugs may be added to single active products that also target liver fluke. Veterinarians may advise the use of single active products in young stock in some situations to target specific parasites.

Single Actives

EPRINEX® Pour-On

Active: Eprinomectin Pack size: 250 mL, 1 L, 2.5 L, 5 L & 25 L WHP: Bobby calf meat: 0 days

Active Dose rate WHP Rain Fast Controls Admin

10KG 1

0 MEAT

0 MILK

Treatment of lactating dairy cattle at calving and/or mid-lactation increases milk solids and can reduce calving to conception time. Eprinomectin is produced by modifying abamectin five-fold to make it more potent and a much better safety profile. Persistent activity against Ostertagia and lungworm.

GENESIS® Injection with B 12 & Selenium

Active: Abamectin Pack size: 4 x 500 mL herd pack WHP: Sheep meat: 28 days, milk: 35 days Aids in the treatment and prevention of selenium and vitamin B 12 (cobalt)

Active Minerals Dose rate WHP

Controls Admin Other*

50KG 1

49 MEAT

49 MILK

B 12

s/c

deficiency, to support growth, immunity and reproduction.

IVOMEC® Plus Injection

Actives: Ivermectin, Clorsulon Pack size: 500 mL Ideal dry-off treatment when a flukicide is necessary. Effective against sucking lice.

Active Dose rate WHP

Controls

Admin

50KG 1

28 MEAT

14 MILK

s/c

*Displayed dose rate, withholding periods, indications and administration route are for this section’s species only. Please see product label for other species details.

Applicators

Cattle Pour-On Gun (65 mL) Gun size: 65 mL Code: 123800 For EPRINEX Pour-On.

Cattle Injector (12 mL) Gun size: 12 mL Code: 146575

For IVOMEC & GENESIS Injections.

CATTLE

Minerals

Injections

COPAJECT

Active: Calcium copper edetate Dose rate: 2 mL (over 4 months of age) Pack size: 200 mL For the treatment and prevention of copper deficiency in cattle, sheep and deer. Actives: Zinc, Manganese, Selenium, Vitamin B 12 Dose rate: 1.5 mL/50 kg (<1 year), 1.5 mL/75 kg (1-2 years), 1.5 mL/100 kg (2+ years) Pack size: 500 mL

Minerals

WHP

Admin Others*

0 MEAT

0 MILK

s/c

MARKS-MIN ZMS with B 12

Minerals

WHP

Admin Other*

0 MEAT

0 MILK

B 12

Zn Mn

s/c

Trace minerals to support growth, reproduction and immune defence, with the energy from vitamin B 12 for optimum health and performance. DO NOT retreat animals for 8 weeks after last treatment.

MARKS-MIN ZMSC with B 12

Actives: Zinc, Manganese, Selenium, Copper, Vitamin B 12 Dose rate: 1.5 mL/50 kg (<1 year), 1.5 mL/75 kg (1-2 years), 1.5 mL/100 kg (2+ years) Pack size: 500 mL

Minerals

WHP

Admin

0 MEAT

0 MILK

Zn Mn Cu

B 12

s/c

Trace minerals to support growth, reproduction and immune defence, with the energy from vitamin B 12 for optimum health and performance. DO NOT retreat animals for 8 weeks after last treatment.

*Displayed dose rate, withholding periods, indications and administration route are for this section’s species only. Please see product label for other species details.

Applicators

MARKS-MIN Injectors

Gun size: 5 mL & 12 mL Code: 162045, 162188

For MARKS-MIN products.

COPAJECT Injector (5 mL)

Gun size: 5 mL Code: 156287

For COPAJECT product.

Boehringer Ingelheim Animal Health New Zealand Ltd Product Guide 2022 19

CATTLE

Minerals

Capsules

COPACAPS

Active: Cupric oxide Dose rate: refer to label Pack size: 50 capsules: 10 g & 20 g 32 capsules: 30 g & 36 g

Minerals

WHP

Admin Others*

0 MEAT

0 MILK

Contain cupric oxide rods inside a gelatine capsule. They can be used for both treatment and prevention of copper deficiency. Administer capsules carefully and with the recommended applicator.

Applicators

Capsule Gun (Small) Gun size: 10 & 20 g Code: 142936

Capsule Gun (Large) Gun size: 30 & 36 g Code: 142937

For COPACAPS.

Therapeutics

BIVATOP® 200

Actives Oxytetracycline 200 mg/mL Dose rate: Long Acting: 1 mL/10 kg (S/C or I/M), Short Acting: 3.3 mL/100 kg (I/V cattle only) Pack size: 100 mL & 250 mL A green light, broad spectrum antibiotic with bacteriostatic activity. Effective against a large number of Gram-positive and Gram-negative pathogenic bacteria, certain rickettsiae and mycoplasma.

WHP

Admin

Others*

21 MEAT

7 MILK

i/m s/c i/v

BUSCOPAN® Compositum

Actives: Hyoscine-n-butylbromide, Dipyrone Dose rate: refer to label Pack size: 100 mL

WHP

Admin

Others*

14 MEAT

12 hrs MILK

Alleriates pain associated with enteritis and digestive disturbance, diarrhoea, oesophageal obstruction, postparturient relief of pain and functional tympanitis.

i/m i/v

*Displayed dose rate, withholding periods, indications and administration route are for this section’s species only. Please see product label for other species details.

CATTLE

Therapeutics

MAMYZIN®

Active: Penethamate hydriodide Dose rate: 5 g daily for 1-5 days or alternatively: 10 g (day 1), 5 g (day 2) Pack size: 5 g & 10 g Milk WHP: 48 hours after 5g daily dosing, or 60 hours after last dose when using 10g followed by 5g Green light, narrow spectrum antibiotic for the treatment of infections caused by Gram-positive bacteria that cause mastitis, respiratory infections, footrot and uterine infections.

WHP

Admin

Others*

7 MEAT

See Label MILK

i/m s/c

METACAM® 20 Solution for Injection

Active: Meloxicam 20 mg/mL Dose rate: Adult cattle: 2.5 mL/100 kg, Calves <50 kg: 0.5 mL/ 20 kg Pack size: 50 mL, 100 mL & 250 mL

Dose rate WHP

Admin

Others*

A long-acting non-steroidal anti-inflammatory drug exerting anti-endotoxic, anti-exudative, antipyretic and analgesic effects. For the alleviation of pain and inflammation associated with mastitis, calf scours, disbudding and respiratory infections.

10 MEAT

3.5 MILK

s/c i/v

100KG

METACAM® 40 Solution for Injection

Active: Meloxicam 40 mg/mL Dose rate: 1.25 mL/100 kg Pack size: 50 mL & 100 mL

Dose rate WHP

Admin Others*

10 MEAT

3.5 MILK

s/c i/v

100KG

PLANIPART®

Active: Clenbuterol hydrochloride Dose rate: 2 mL/100 kg Pack size: 50 mL

Dose rate WHP

Admin

12 MEAT MILK 2.5

For the relaxation of uterine muscle and abolition of contractions. This helps to enable obstetric intervention during difficult calvings and to delay the onset of parturition in cattle when required.

i/m i/v

100KG

*Displayed dose rate, withholding periods, indications and administration route are for this section’s species only. Please see product label for other species details.

Boehringer Ingelheim Animal Health New Zealand Ltd Product Guide 2022 21

SUCKING AND BITING LICE Linognathus vituli, Haematopinus spp. , Solenopotes spp. Bovicola bovis .

LUNGWORM Dictyocaulus viviparus

DISTRIBUTION: All over NZ. PERFECT CONDITIONS: Winter coats. Animals almost always have a mixed infection of both biting and sucking lice. SIGNS: Can be seen by the naked eye as little black/brown dots around the eyes and neck. Biting lice are very itchy and cattle will rub on fences and other cattle. TREATMENT: Only a pour-on product has good efficacy against both biting and sucking lice. TIPS: The whole life cycle takes place on the cow. Sucking lice suck blood and so oral and injectable products are often able to kill sucking lice as the drugs in the blood are sucked by the louse. The MLs often have persistent activity. No drug kills the eggs (nits). Adult lice lay low numbers of eggs and so will take a long time to build up a large population meaning that one treatment a season is usually enough to control lice. RESISTANCE: None currently reported in cattle in NZ.

DISTRIBUTION: All over NZ. PERFECT CONDITIONS: Warm and wet. Irrigated blocks. SIGNS: Group coughing, faster breathing 3-4 weeks after challenge. Immunity develops quickly but needs regular challenge to maintain. Can be seen the year after a particularly dry summer (low challenge year) or if naïve animals are introduced to infected pasture. TREATMENT: All classes of drench have good efficacy. The MLs have varying levels of persistent activity. TIPS: Larvae hatch from eggs in the cow and so will not show up in faecal egg counts. Disease can be seen before larvae are present in the faeces. Larvae can encyst in the calf over winter. RESISTANCE: No resistance has been reported in NZ.

LIVER FLUKE Fasciola hepatica

GUTWORMS Ostertagia ostertagi, Cooperia oncophora , Trichostrongylus spp.

DISTRIBUTION: Predominates on the west coast of the South Island, although present all over NZ. PERFECT CONDITIONS: Areas with stagnant water. Requires the mud snail to complete its life cycle. The mud snail is found around stagnant water all over NZ. SIGNS: Low growth rates, reduced milk production and fertility. Reported on kill sheets. TREATMENT: Generally, only flukicides will kill liver fluke. These are different from the BZ, Lev and MLs that are used to kill gutworms and lungworm. Some flukicides kill liver fluke from 2 weeks of age and some only kill adult fluke. TIPS: Use knowledge of the lifecyle to determine the likely age of the liver fluke population in infected cattle, bearing in mind withholding periods and administration method, to determine which product to use.

PERFECT CONDITIONS: Warm and wet. Irrigated blocks. SIGNS: Poor growth rates, reduced milk production. Diarrhoea if heavy challenge. TREATMENT: Cattle under 18 months of age require treatment with a combination drench (more than one drench family). Triple combinations are only available for oral drenching. Single active MLs that do not partition in milk are best for adult dairy cattle. TIPS: All the gutworms encyst over winter inside the calf allowing reinfection in spring. Adult dairy cattle will increase their milk solids on average by 0.03kgMS/day after treatment with EPRINEX Pour-On. RESISTANCE: Significant resistance seen in Cooperia against ML and BZ. Resistance in Ostertagia against Lev and low levels to BZs and MLs.

Adult liver fluke can live for 2 years in the livers of cattle. RESISTANCE: None currently reported in cattle in NZ.

Boehringer Ingelheim Animal Health New Zealand Ltd Product Guide 2022 23

CATTLE

Dosing Guide

PACK SIZE

DOSE RATE

100 kg

200 kg

300 kg

400 kg

500 kg

600 kg

50 mL

1 mL/50 kg

200 mL

1 mL/50 kg

100

500 mL

1 mL/35 kg

175

500 mL

1 mL/50 kg

250

125

1 L

1 mL/10 kg

100

1 L

1 mL/20 kg

200

100

2 L

1 mL/35 kg

700

350

233

175

140

116

2.5 L

1 mL/10 kg

250

125

2.5 L

1 mL/20 kg

500

250

166

125

100

2.5 L

1.5 mL/50 kg

833

416

277

208

166

138

3 L

1 mL/35 kg

1050

525

350

262

210

175

5 L

1 mL/10 kg

500

250

166

125

100

5 L

1 mL/20 kg

1000

500

333

250

200

166

5.5 L

1 mL/10 kg

550

275

183

137

110

5.5 L

1 mL/20 kg

1100

550

366

275

220

183

10 L

1 mL/10 kg

1000

500

333

250

200

166

10 L

1 mL/20 kg

2000

1000

666

500

400

333

20 L

1 mL/10 kg

2000

1000

666

500

400

333

20 L

1 mL/20 kg

4000

2000

1333

1000

800

666

25 L

1 mL/10 kg

2500

1250

833

625

500

416

Number of cattle treated on pack size and dose rate.

Ensure young stock become future high producers through improved health, growth and energy at: futureproducers.co.nz

24 *Displayed dose rate, withholding periods, indications and administration route are for this section’s species only. Please see product label for other species details.

EQUINE PRODUCTS

THERAPEUTICS SEDATIVES

EQUINE

Therapeutics

PRASCEND® Tablets for Horses

Active: Pergolide 1 mg (as pergolide mesylate) Dose rate: refer to label Pack size: 60 tablets & 160 tablets For the control of clinical signs associated with Pituitary Pars Intermedia Dysfunction (PPID) (Equine Cushing’s disease) in horses and ponies. Active: Meloxicam 15 mg/mL Dose rate: 0.6 mg/kg, once daily for up to 14 days Pack size: 100 mL Alleviation of inflammation and relief of pain in both acute and chronic musculoskeletal disorders in horses.

WHP

Admin

63 MEAT

METACAM® Oral Suspension for Horses

WHP

Admin

28 MEAT

METACAM® 20 Solution for Injection

Active: Meloxicam 20 mg/mL Dose rate: Single i/v injection 3 mL/100 kg can continue, 24 hrs later, with METACAM® 15 mg/mL Oral Suspension for Horses Pack size: 50 mL, 100 mL & 250 mL Single use. For rapid initiation therapy of musculoskeletal disorders and relief of pain associated with colic. Active: Meloxicam 40 mg/mL Dose rate: Single i/v injection 1.5 mL/100 kg can continue, 24 hrs later, with METACAM® 15 mg/mL Oral Suspension for Horses Pack size: 50 mL & 100 mL

Dose rate WHP Admin

Others*

100KG 3

28 MEAT

i/v

METACAM® 40 Solution for Injection

Dose rate WHP Admin Others*

100KG 1.5

28 MEAT

i/v

Single use. For rapid initiation therapy of musculoskeletal disorders and relief of pain associated with colic.

BUSCOPAN® Compositum

Actives: Hyoscine-n-butylbromide, Dipyrone Dose rate: refer to label Pack size: 100 mL

WHP Admin

Others*

2 MEAT

Treatment of horses with spasmodic colic, gastroenteritis, diarrhoea and oesophageal obstruction.

i/v

HYONATE®

Actives: Sodium hyaluronate Dose rate: i/v: 4 mL (2 vials–40 mg), i/a: 2 mL (1 vial–20 mg) Pack size: 2 x 2 mL

WHP Admin

0 MEAT

i/v i/a

For the treatment of non-infectious acute synovitis in horses.

*Displayed dose rate, withholding periods, indications and administration route are for this section’s species only. Please see product label for other species details.

EQUINE

Therapeutics

VENTIPULMIN® Bronchodilator for Horses

Active: Clenbuterol hydrochloride Dose rate: 1.25 mL/50 kg, twice (on first day)^ Pack size: 50 mL WHP: refer to label

Admin

For the treatment of all conditions where constriction of the airways occurs. ^Follow treatment with VENTIPULMIN Oral Bronchodilater for Horses for a minimum period of 5 days.

i/m i/v

VENTIPULMIN® Oral Bronchodilator for Horses

Active: Clenbuterol hydrochloride Dose rate: 2.5 g/50 kg twice daily, for 10 days Pack size: 500 g WHP: refer to label

Admin

Relief of bronchospasm and airway obstruction associated with: bacterial infection, during and after the infective phase; bronchitis; bronchopneumonia; respiratory allergies; exercise-induced bronchospasm; and all conditions where narrowing of the small airways is a contributing factor to the problem.

MAMYZIN®

Active: Penethamate hydriodide Dose rate: 5 g daily, for 1-5 days Pack size: 5 g & 10 g (10 vials per carton)

WHP

Admin

Others*

7 MEAT

For the treatment of infections caused by Gram-positive bacteria that cause mastitis, respiratory infections, footrot and uterine infections.

i/m s/c

*Displayed dose rate, withholding periods, indications and administration route are for this section’s species only. Please see product label for other species details.

Sedatives

SEDIVET®

Active: Romifidine hydrochloride Dose rate: refer to label Pack size: 20 mL

WHP

Admin

6 MEAT

For sedation of horses to facilitate handling, examination and treatment, and as a pre-medication agent prior to general anaesthesia. Do not use in pregnant mares.

i/v

Boehringer Ingelheim Animal Health New Zealand Ltd Product Guide 2022 27 Boehringer Ingelheim Animal Health New Zealand Ltd Product Guide 2022 27

COMPANION ANIMAL PRODUCTS

PARASITICIDES Parasiticides

Deworming Protocols

THERAPEUTICS

Inflammation & Pain Therapeutics Antibiotics

COMPANION ANIMAL

Parasiticides

The flea lifecycle is comprised of four developmental stages: egg, larva, pupa and adult flea. The time it takes for a new flea to develop can vary from as little as 12 days to as long as 325 days. As flea pupae can remain dormant in the environment for at least 6 months, it may take some time for flea eggs to emerge as adult fleas. Adult fleas, the lifecycle stage you see on the pet, make up just 5% of the total flea population. Ninety-five percent of the population is made up of eggs, larvae and pupae, which can be found in the pet’s environment. Flea treatment of all household pets is a year round commitment because fleas can be active in all seasons. When a pet goes outside of the home environment, it can come into contact with fleas from eggs that have been deposited, even several months previously, by untreated pets or wildlife. MONTHLY WORMING: is recommended to help control zoonotic risk from roundworm, and is especially recommended for pets that are considered higher risk (those that meet one or more of the following: have access to the outdoors, live with children, the elderly or immunocompromised, hunt/catch wild prey such as rodents and birds).

Parasiticides

NEXGARD® SPECTRA for Cats

Actives: Esafoxolaner, eprinomectin, praziquantel Dose rate: 0.3 mL (0.8–2.4 kg), 0.9 mL (2.5-7.4 kg). For cats over 7.5 kg see pack for details Pack size: Triple packs

Active Admin

Controls

Registered

For the treatment, control and prevention of flea, tick, ear mites and worms including tapeworms. NEXGARD SPECTRA for Cats is an all-in-one topical parasiticide that provides broad spectrum protection against both external & internal parasites. Unique applicator ensures complete, accurate and easy dosing. Safe for kittens from 8 weeks of age. Monthly treatments are recommended for the prevention and control of parasite infestations.

NEXGARD SPECTRA®

Actives: Afoxolaner, milbemycin oxime Monthly treatment: Five dosage strengths: Very Small (2-3.5 kg), Small (3.6-7.5kg), Medium (7.6-15 kg), Large (15.1-30 kg), Extra Large (30.1-60 kg). For over 60 kg, administer the appropriate

Active Admin Flavour

Controls

Registered

combination of whole chewables Pack size: Single & Triple packs

NEXGARD SPECTRA is a delicious, gentle, monthly chew that provides dogs with the most comprehensive parasite protection in a single dose. NEXGARD SPECTRA kills fleas fast, consistently and persistently for the entire duration of the treatment. It treats for ticks and mites, and has the added benefit of protecting against roundworms, hookworms and whipworms. When used monthly, NEXGARD SPECTRA is highly effective in preventing flea tapeworm. As this is an oral treatment, it is not affected by bathing or swimming; it can be given with or without food.

NEXGARD® Chewables

Active: Afoxolaner Monthly treatment: Four dosage strengths: Very Small (2-4 kg), Small (4.1-10 kg), Medium (10.1-25 kg), Large (25.1-50 kg), for over 50kg, administer the appropriate

Active Admin Flavour

Controls

Registered

combination of whole chewables Pack size: Single & Triple packs

NEXGARD Chewables are a delicious, gentle, monthly chew that provides excellent parasite prevention and control for dogs from fleas, ticks, mites and prevention of flea tapeworm. NEXGARD kills fleas fast, consistently and persistently for the entire duration of the treatment. When used monthly, NEXGARD is highly effective in preventing flea tapeworm. As this is an oral treatment, it is not affected by bathing or swimming; it can be given with or without food.

Boehringer Ingelheim Animal Health New Zealand Ltd Product Guide 2022

COMPANION ANIMAL

Parasiticides

BROADLINE® Spot-on Solution for Cats

Actives: Fipronil, (S)-methoprene, eprinomectin, praziquantel Dose rate: 0.3 mL (0.8–2.4 kg), 0.9 mL (2.5-7.4 kg). For cats over 7.4 kg see pack for details Pack size: Single & Triple packs

Active Admin

Controls

Registered

For the treatment, prevention and control of flea, tick and biting lice infestations and flea allergy dermatitis, and the treatment and control of roundworms, hookworms, lungworms and tapeworms. An all-in-one topical parasiticide that provides broad spectrum protection against both external & internal parasites. Unique applicator ensures complete, accurate and easy dosing. Safe for kittens from 8 weeks of age. Monthly treatments are recommended for the prevention and control of parasite infestations.

FRONTLINE® Plus for Cats

Actives: Fipronil, (S)-methoprene Dose rate: One pipette per cat up to 10 kg Pack size: Triple & Six packs

Active Admin

Controls Registered

FRONTLINE PLUS spot-on solution is a topical application for the treatment of fleas, ticks and biting lice. Monthly treatment is recommended to control and prevent flea infestations. FRONTLINE PLUS kills 98-100% of fleas within 24 hours and will persist against new flea infestations for at least one month. Ticks will be killed within 48 hours for one month. One treatment is effective against biting lice. FRONTLINE PLUS also contains (S)-methoprene which acts as an insect growth inhibitor. It prevents the multiplication of fleas by inhibiting the development of the immature stages of growth (eggs, larvae and pupae) for at least one month. FRONTLINE PLUS has an excellent safety profile, and has been trusted by kiwis for more than 25 years. Safe for use on breeding, pregnant and nursing cats.

FRONTLINE® Plus for Dogs

Actives: Fipronil, (S)-methoprene Dose rate: One pipette according to weight: Small (up to 10 kg), Medium (10-20 kg), Large (20-40 kg) & Extra Large (40-60 kg). For dogs over 60 kg administer the appropriate combination of pipettes Pack size: Triple packs

Active Admin

Controls Registered

FRONTLINE® Spray

Active: Fipronil Dose rate: Apply 3-6 mL/kg, depending on the length of hair, See pack for details Pack size: 100 mL & 250 mL

Active Controls Registered

FRONTLINE Spray is a topical application for the treatment of flea infestations, ticks, and lice and is ideal for use on kittens and puppies from 2 days old. FRONTLINE Spray kills 98-100% of fleas within 24 hours and will persist against new flea infestations for at least one month. Ticks will be killed within 48 hours for up to 4 weeks. FRONTLINE Spray has an excellent safety profile, and has been trusted by kiwis for more than 25 years. Safe for pregnant and nursing dogs.

*Displayed dose rate, withholding periods, indications and administration route are for this section’s species only. Please see product label for other species details.

Whipworm (dog only)

Tapeworm

Roundworm

Hookworm

Lungworm (cat only)

The importance of pre-patent periods

PRE-PATENT PERIOD

Most anthelmintics do not have residual activity – they kill worms present at the time of administration but provide no forward protection. Deworming protocols should therefore be designed to kill newly acquired parasites before they can shed infective forms (eggs or larvae).

The time period between infestation with a parasite and when infective forms

(eggs or larvae) are detectable.

THE DOSING INTERVAL SHOULD BE LESS THAN THE PRE-PATENT PERIOD FOR WORMS OF ZOONOTIC CONCERN.

The significance of pre-patent periods and deworming intervals e.g. roundworm ( Toxocara canis ) Pre-patent period – approximately 5 weeks

Monthly deworming eliminates newly acquired roundworms before they begin shedding eggs, reducing environmental contamination and minimising zoonotic risk.

3 months

2 months

1 month

Deworming Every Month

Pre-patent period

Worms killed before they begin shedding

1 month

2 months

3 months

Deworming Every 3 Months

Pre-patent period

Faecal shedding of eggs

Up to 200, 000 eggs per female worm per day for 42 days (before next dose given) = 8.4 million eggs in the enviroment from a single worm!

Boehringer Ingelheim Animal Health New Zealand Ltd Product Guide 2022 31

Page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Page 7 Page 8 Page 9 Page 10 Page 11 Page 12 Page 13 Page 14 Page 15 Page 16 Page 17 Page 18 Page 19 Page 20 Page 21 Page 22 Page 23 Page 24 Page 25 Page 26 Page 27 Page 28 Page 29 Page 30 Page 31 Page 32 Page 33 Page 34 Page 35 Page 36

www.boehringer-ingelheim.com

Made with FlippingBook - PDF hosting