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Stålman 2011.
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Stålman A, Berglund L, Dungnerc E, Arner P, Felländer-Tsai L. Temperature- sensitive release of prostaglandin E₂ and diminished energy requirements in synovial tissue with postoperat ive cryotherapy: a prospective randomized study after knee arthroscopy. J Bone Joint Surg Am. 2011 Nov 2;93(21):1961-8.
Design: Prospective Randomised Study Subjects: 40 patients undergoing knee arthroscopy Methods: 20 patients (50%) were randomized to receive postoperative cooling and compression ( Aircast Cryo/Cuff ). Outcomes included: Postoperative pain (VAS), knee temperature, microdialysis (to assess blood flow, metabolic rate). Results: • Application of the cooling and compression device after knee arthroscopy significantly lowered the temperature in the operatively treated knee. • The temperature at each of the locations (skin, joint capsule, and intra- articularly) in the operatively treated knee was significantly lower in the Cryo/Cuff group than in the untreated group. • The cryo/cuff appeared to decrease inflammation , as indicated by a temperature-sensitive decrease in the PGE2 concentration. • The hypothermia also decreased the metabolic rate of the synovial tissue and thus decreased energy requirements. The authors note that this reduced metabolic activity confers a protective effect on ischemic tissue.
Key message: Significant decrease of knee temperature and associated pain & inflammation marker PGE2 with postop Knee Cryo/Cuff application.
iEnovis
Pubmed
iEnovis
Pubmed
• No effect of the compression and cooling on postoperative pain was detected, potentially due to a small sample size and the procedure performed (in comparison to ACL reconstruction or Arthroplasty).
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