Cold Therapy Clinical Research Overview

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Kullenberg 2006

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Kullenberg B, Ylipää S, Söderlund K, Resch S. Postoperative cryotherapy after total knee arthroplasty: a prospective study of 86 patients. J Arthroplasty. 2006 Dec;21(8):1175-9.

Design: Prospective randomised controlled trial.

Subjects: 86 consecutive patients undergoing unilateral TKA.

Methods: patients were randomized to

• Treatment with Aircast Cryo/Cuff for 3 days after TKR (41 patients)

• Standard treatment: epidural analgesia for 3 days, followed by NSAIDs and opioids (45 patients). Outcomes included: Pain (VAS). Analgesic consumption, ROM for flexion and extension (Pre, day 1 post-op, discharge, 3 weeks post-op, weight bearing, total time in hospital.

Key message: Better pain control, ROM improvement and shorter hospital stay with the Aircast Cryo/Cuff after TKA.

Results:

• VAS pain scores and analgesic consumption were equal in both groups. Pain control for patient and nursing staff was easier with cold compression. • ROM at discharge was 75° in cold compression group vs. 63° in control group. By 3 weeks follow-up, ROM was 99° vs. 88° respectively. • Mean time in hospital averaged 4.8 days in the cold compression group and 6.2 days for the control group. This means cost savings: the list price of the Cryo/Cuff is 50 euros, while 24 hours of orthopaedic hospital care costs 325 euros.

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• Weight load in the operated leg was equal in both groups.

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