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Holmström 2005
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Holmström A, Härdin BC. Cryo/Cuff compared to epidural anesthesia after knee unicompartmental arthroplasty: a prospective, randomized and controlled study of 60 patients with a 6-week follow-up. J Arthroplasty. 2005 Apr;20(3):316-21.
Design: Prospective randomised controlled study.
Subjects: 60 patients with a diagnosis of osteoarthrosis undergoing primary, unicondylar knee arthroplasty and were scheduled to follow the present knee- rehabilitation program were considered for the trial.
Methods: 61 knees were randomized into 3 groups:
1. Aircast Cryo/Cuff : traditional analgesics + CC applied immediately after skin closure and before release of the tourniquet. Treatment continued without interruption for 48 hours. 2. Epidural anaesthesia (EDA): traditional analgesics + continuous EDA administration for 48 hours
Key message: Aircast Cryo/Cuff is a viable alternative for pain management after TKA, because in this study it was as effective as epidural anaesthesia for pain reduction, while well tolerated, non-invasive and risk-free.
3.
Control: received only traditional analgesics
Outcomes included: blood loss, pain (rest/in-motion), morphine consumption, swelling, ROM.
Results:
• No significant difference between groups was detected with respect to subjective pain, bleeding, swelling, range of motion, and function. • The consumption of morphine was, however, significantly higher in the control group the first 24 hours than both the EDA group ( P < .001) and the Cryo/cuff group ( P = .028).
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• There was no significant difference in morphine consumption between the 2 treatment groups.
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