Youthful Brain
studies have shown that the inflammation marker IL-17 is linked to the damage and impairment of blood brain barrier function; an important barrier that filters the blood to prevent harmful compounds from entering the brain. By helping to reduce the levels of inflammation markers, Sibelius TM : Sage may help to maintain the integrity of the blood brain barrier as well as support a healthy flow of blood to the brain. A researched-backed solution for cognitive performance Sibelius TM : Sage has been shown to inhibit the action of acetylcholinesterase – the enzyme that breaks down the neuro- transmitter acetylcholine. Acetylcholine is found in the brain in areas associated with attention, memory, and motivation. In addition, we have seen Sibelius TM : Sage
in multiple studies that Sibelius TM : Sage has anti-inflammatory effects, and has the potential to reduce levels of inflammation throughout the body and help maintain cognitive health. Inflammation markers Two key inflammation markers relevant to cognitive health, have shown a robust response to Sibelius TM : Sage – these are VCAM-1 and IL-17. Studies in older adults in the US have shown that higher levels of the inflammation marker VCAM-1 are correlated with poor cognitive performance as well as reduced cerebral blood flow (the amount of blood flow to the brain). This may be due to inflammation- induced atherosclerosis stiffening and reduced elasticity of the blood vessels, which can lead to a reduction in the flow of blood reaching the brain. Similarly,
has similar effects on enzymes involved in the breakdown of other neurotransmitters, including dopamine and serotonin (also referred to as the happy hormones!). This adds to the body of evidence suggesting that Sibelius TM : Sage helps maintain healthy and youthful levels of neurotransmitters in the brain, which contributes towards its near- immediate cognitive performance benefits, as well as supporting your cognitive health over the longer-term. Sibelius TM : Sage is a clinically researched sage extract that provides a fast lift to cognitive performance for individuals seeking a natural boost. Dr Kieron Edwards BSc Hons, PhD, MBA is the Chief Scientific Officer at Sibelius Natural Products.
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ISSUE 65 • 2022
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