Surface modifications of titanium alloys for biomedical applications Justynne Fabian, Brendan Duffy, Susan Warren Centre for Research in Engineering Surface Technology (CREST), Technological University Dublin – City Campus, FOCAS Research Institute, Camden Row, Dublin 8, Ireland. Titanium dioxide nanotubes (TiO 2 NTs) have been extensively studied over the last few decades. From the early generations of TiO 2 NTs featuring short NT lengths and ribbed structures along the NT walls, to the modern generations displaying highly self-ordered NTs with longer lengths, these structural improvements have resulted in the pursuit for additional functionalisation to better facilitate many different fields including energy storage, aerospace, and biomedical applications. This project employs anodisation of titanium alloys to form ordered NTs using a neutral, aqueous-based electrolyte with moderate experimental conditions. Incorporation of antimicrobial agents into TiO 2 NTs was achieved by successful electrodeposition of silver and copper nanoparticles with various morphology and distribution ( Figure 1 ). Based on the fact that modification of the TiO 2 NT structure and electrodeposited nanoparticles is easily obtainable by the variation of electrochemical parameters, the current work attempts to address two highly clinically-relevant issues related to implant failure: poor osseointegration of the implant with the surrounding bone, 1 and implant associated infections (IAIs). 2
References 1. Q. Wang, P. Zhou, S. Liu, S. Attarilar, R. L. W. Ma, Y. Zhong and L. Wang, Nanomaterials , 2020, 10 , 1–27. 2. Z. Yuan, Y. He, C. Lin, P. Liu and K. Cai, J. Mater. Sci. Technol. , 2021, 78 , 51–67.
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