Longevity Medical Institute: Multipotent vs Pluripotent Cell

Restricted Differentiation:

Robust Paracrine Signaling: When given by IV, most stem cells work not by directly becoming new tissue but by releasing helpful substances—like growth factors and cytokines—that reduce inflammation and help the body repair itself.

Their limited range means they are less likely to form unwanted tissue types, reducing the risk of uncontrolled growth.

Enhanced Genetic Stability: Because they don't divide as rapidly and have a limited differentiation range, multipotent cells tend to maintain a stable genetic profile over time.

Simpler Culture Requirements:

Multipotent cells are generally easier to grow in the lab, and results in fewer chances for them to develop harmful mutations.

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