SBMS Newsletter Issue 05

September 2021 | Issue 05

photo was taken before the pandemic

• CoronaTrend: A web-based application to identify SARS-CoV-2 potential critical mutations • HKU Biomedical Sciences Summer Academy 2021 • RGC Theme-based Research Scheme & Research Fellow Scheme awarded to School members • HKUMed identifies an important gene linking the two hallmark pathological features: Amyloid β (A β ) plaques and neurofibrillary tangles (NFT) in Alzheimer’s disease (AD)

www.sbms.hku.hk

Welcome Message

The COVID-19 pandemic has affected us in many different ways. We should be proud of not only taking the lead to tackle SARS-CoV-2 with high-quality biomedical research, but also striking a balance between normal university life and the need of keeping COVID-19 at bay. SARS-CoV-2 and COVID-19 have provided great opportunities for Teaching & Learning, Research & Innovation, as well as Knowledge Exchange & Global. Science plays a central role to bring about the beginning of the end of the pandemic. The technical terms of mRNA vaccine and herd immunity have never been so popular among us and in the community. As biomedical scientists, we should embrace the new opportunities and redouble our effort to discover new drug targets and to develop better vaccines and drugs. These are our obligations and responsibilities. The new academic year has just begun with full resumption of f2f teaching. We look forward to a new normal, which will certainly be much better than the past two semesters.

Professor Dong-Yan Jin Member, Executive Committee School of Biomedical Sciences

Teaching and Learning Summer Intern at Dr. Kelvin To’s Lab, Department of Microbiology Project CoronaTrend: A web-based application to identify SARS-CoV-2 potential critical mutations Feature Story

Throughout developing CoronaTrend, I have garnered a lot of invaluable experience that would take me a long way. As a novice in the world of bioinformatics and programming, learning a new language and using it on the fly in a narrow timeframe of two months is certainly challenging. However, through reading papers, cooperating with my team, and a lot of trial and error, I can achieve results I have not even dreamt of, including getting the project featured in GISAID, the largest SARS-CoV-2 sequence database in the world. Admittedly, CoronaTrend still has a lot of space for enhancements, which is why in the following months I will continue my work on improving the site. This includes integrating GISAID's API to CoronaTrend to allow real-time updates to the graph, allowing insertion mutations to be visualized, identifying co-mutations, and other UI performance optimizations. I really hope that whether the impact be large or small, CoronaTrend can serve as a useful tool that can aid others in understanding SARS-CoV-2. Last but not least, I would like to thank Mr. Jonathan Ip, Dr. Kelvin To, and the rest of the team for giving me the opportunity to have a taste of bioinformatics research this summer. Without their kind guidance and help, this project would not have been possible in the first place. In the future, I would devote my time to my passion for CoronaTrend and other bioinformatics projects, while actively seeking other interests in the field of research and medicine.

Thomas Tze-To Chan BBMS Year 2

During my summer internship, I have created CoronaTrend (https://coronatrend.live) , a web-based application that allows people to view the prevalence of different SARS-CoV-2 mutations through time. CoronaTrend also has a variety of filtering options, such as filtering by gene, country, and lineage. By tweaking the filters, it is possible to find interesting emergence patterns which may reveal mutations currently on the rise. This project isn't originally intended to be a web program. Rather, it was first created to show static images of prevalence trends of different SARS-CoV-2 mutations. However, as I continued my work on the project, I realized that amid the COVID-19 pandemic, making the data publicly available online will benefit many more people as there are currently no other public resources available providing similar data. This gave me the idea of creating interactive graphs that everyone can play and experiment with, which eventually evolved into the current CoronaTrend.

Feature Story Research & Innovation

Research Grants Council’s Theme-based Research Scheme (TRS) 2021/22

Project Title

Ecology, molecular virology and pathogenesis of SARS-CoV-2: From bedside to bench and back

Project Coordinator

Prof. Dong-Yan Jin

Project Description

On the basis of our study and discoveries of coronaviruses (CoVs) in the past 18 years, multidisciplinary research in this project will be carried out in three intertwined areas to address key scientific questions surrounding ecology, molecular virology and pathogenesis of SARS-CoV-2, thereby paving the avenue to conceptually new approaches for early diagnosis, prevention and treatment of COVID-19, essential to bringing an end to the pandemic. First, we will derive new insights into the origin and evolution of SARS-CoV-2 by analyzing one of the world’s largest collection of samples from bats and other animals. Concurrently, we will continue to discover emerging variants of SARS-CoV-2 with altered pathogenicity and transmissibility. We will also define the mechanism of asymptomatic SARS-CoV-2 infection in bats and humans. This will provide the materials and basis for the next part of our project. Second, we will unravel new mechanism of SARS-CoV-2 entry and replication. We will also characterize the roles of several lineage-specific accessory proteins in SARS-CoV-2 biology and pathogenesis. Forward genetic screens based on RNAi and CRISPR technology will be performed to identify novel host dependency and restriction factors. Finally, we will pursue translational research to revolutionize diagnosis, vaccine development and treatment of COVID-19. Concepts established in our project will be harnessed to design and develop new strategies, methods and leads for early and rapid diagnosis, immunization with live attenuated and synthetic vaccines, as well as therapeutic treatment targeting either the virus or the host.

Research Grants Council’s Research Fellow Scheme (RFS) 2021/22 Project Title An immune perspective on exploiting stemness as a cancer cell vulnerability for the treatment of liver cancer

Project Coordinator

Dr. Stephanie Ma

Project Description

Hepatocellular Carcinoma (HCC) is a particularly prevalent and deadly disease in Hong Kong and China. Despite improvements in the outcome of patients with HCC, the overall prognosis of this cancer is still unsatisfactory because of late presentation, drug resistance and frequent tumor recurrence. PD-1 blockade represents a major therapeutic avenue in anti-HCC immunotherapy; but there remain serious limitations including the accurate assessment and prediction of tumor response and overcoming the immunosuppressive effects of the tumor microenvironment. Cancer stemness is a property that is now widely accepted to be associated with drug resistance, tumor relapse and the general unfavorable outcome of HCC. The enhanced ability of cancer stem cells (CSCs) to give rise to new tumors suggests that these cells likely have an advantage in evading immune detection and elimination. Our pilot data suggests that activation of a stemness program in HCC appears to limit anti-tumor immune responses. We propose a project on liver CSC immunology that will encompass looking at cancer stemness and their connection with A-to-I RNA editing, mutation-driven pathway activation and immune evasion. Findings of this project will also aid to improve patient stratification for immuno-oncology therapy.

CONGRATULATIONS

Knowledge Exchange & Global Feature Story

The School of Biomedical Sciences held, with support from the Croucher Foundation, the inaugural HKU Biomedical Sciences Summer Academy on Aug 2-6, 2021. The event aims to raise secondary school students and teachers’ awareness about biomedical sciences and how biomedical sciences and related research can benefit the human mankind. Program leverages on the unique strengths in pioneering research areas of the School and includes hands-on experiments on Planarians, Protein Crystallography and Cancer Drug Discovery, as well as talks on CRISPR editing, Human Anatomy with VR, Biomedical Entrepreneurship, Big Data and Bioinformatics, a Biomedical Sciences related career roundtable, and more. We have engaged 30 students and their teachers, from 3 different local secondary schools, and is delighted to have received positive and encouraging feedbacks from the participants. HKU Biomedical Sciences Summer Academy 2021 Aug 2-6, 2021

Participating Schools · Buddhist Tai Hung College

· Homantin Government Secondary School · Fukien Secondary School (Siu Sai Wan)

Our most sincere gratitude to all School members involved. Without their help, the Summer Academy would not have been possible!

Project Instructors/Advisor & Technical Support Staff Prof. Danny Chan, Dr. Raymond Chang, Dr. Lydia Cheung, Dr. Martin Cheung, Dr. Rocky Cheung, Dr. Clive Chung, Dr. Joanna Ho, Dr. Joshua Ho, Prof. Michael Huen, Dr. Masayo Kotaka, Dr. Cora Lai, Dr. Stephanie Ma, Prof. Julian Tanner, Dr. Alan Wong, Dr. Jian Yang, Ms Jess Chan, Ms Vanessa Choi, Mr Nelson Dung, Mr Siu Pang Ho, Mr Edmond Kam, Ms Alice Lui, Dr. Sophia Ma, Ms Andrea Ng, Ms Gloria Tse, Mr Anthony Tsang, Ms Connie Wong, Ms Dana Wong and Mr Patrick Wong Staff & Student Helpers Ms Charmaine Chan, Mr Jordan Chan, Ms Jessie Ho, Mr Joseph Ho, Ms Mun Kay Ho, Miss Kelly Hong, Dr. Victor Huang, Ms Amy Koo, Ms Rachel Kwan, Ms Yoyo Lai, Miss Coco Lam, Mr Terence Lee, Mr Manton Leung, Mr Jason Li, Ms Sherry Li, Miss Venus Lou, Miss Toni Man, Mr Winston Mak, Miss Angel Ng, Ms Gloria Ng, Mr Charles Ouyang, Mr Andrew Poon, Ms Beth So, Mr Michael Wang, Dr. Eric Wong, Ms Audrey Yau and Dr. Chu Zhang

Congratulations Awards & External Grants

Dr Veronica Lam Prizes (2021) The following students have been awarded the Dr Veronica Lam Prizes:

Staff Awards

Mr Yuten Liang BBMS Year 1 student

Miss Xiyue Pan BBMS Year 2 student

BSMB Medal Lecture Award Prof. Kathryn Song Eng Cheah has been awarded the BSMB Medal Lecture Award.

Open your mind to things you aren’t looking for. Don’t discard any research findings simply because they don’t fit in what you think the answers should be. Be persistent and brave enough to receive critical feedback - that’s how we all learn.

Mr Michael wang BBMS Year 3 student

Miss Claudia Simone Lee BBMS Year 4 student

- Prof. Kathryn Cheah

Deans’ Honours List BBMS Year 1 students - Mr Alexander Chun Lok Chan, Mr Tze To Chan, Mr Man Hei Cheng, Mr Wing Yiu Cheng, Miss Wai Yi Chiu, Mr Siu Wa Chui, Miss Yin Yee Ho, Mr Darren Lam, Mr Sanghyun Lee, Mr Yat Long Leong, Mr Yuteng Liang, Mr Ching Hon Mak, Miss Asra Sainju, Miss Laura Simone Elisabeth Schulz, Miss Yui Ching Shek, Miss Xingyu Shen, Mr Tsz Him So, Miss Yauvani Sudarshan, Miss Siu Kuk Cirrus Yiu BBMS Year 2 students - Miss Sheung Man Chan, Mr Hok Man Edmund Cheng, Miss Wai Man Chick, Miss Nadya Christina, Mr Wang Ho Chung, Miss Tanvi Falodiya, Miss Kyungmin Kim, Mr Cheuk Hang Nicolas Lau, Miss Ka Yi Lee, Miss Ka Ki Tiffany Luk, Miss Wing Tung Ng, Miss Xiyue Pan, Miss Ar Wou Joivia So, Miss Charlotte Theodora So, Miss Cheuk Ying Tse, Mr Kwan Yiu Tse, Miss Yee Lok Tsoi, Miss Lok Sze Yeung, Miss Yui Yan Hillary Yip BBMS Year 3 students - Miss Wing Yin Au, Miss Eugene Hwang, Miss Kyu Eon Jeon, Mr Hyun Woo Kim, Mr Yichen Li, Mr Michael Wang, Miss Woojeong Yang, Miss Ching Yun Yu, Miss Wing Wa Yu BBMS Year 4 students - Mr Yu Cheng, Miss Po Chit Pucci Fung, Mr Wai Lam Ho, Miss Tin Yan Koo, Mr Hiu Fung Jeremy Kuen, Mr Yat Hei Hugo Kwong, Mr Sing Chi Lam, Mr Yat Kwan Lam, Miss Claudia Simone Lee, Mr Tsz Fung Jacky Luk, Miss Yu Yan Kay Ng, Miss Sze Wah Tsang, Miss Amy Yeung External Grants Health and Medical Research Fund (HMRF) - A grand total of HK$7,437,168 has been awarded to Prof. Dong-Yan Jin, Dr. Martin Cheung, Dr. Bo Gao, Dr. Man Tong and Dr. Wilson Chan.

Conferment of Chair Professor Title Prof. Ren Sun has been conferred the title of Chair Professor with effect from Jul 1, 2021.

Students Awards

HKU Postgraduate Fellowships in Integrative Medicine 2021-22 Miss Hiu Lam Rachel Kwan, PhD candidate in Dr. Chi Wai Lee’s lab, has been awarded the HKU Postgraduate Fellowships in Integrative Medicine 2021-22. Yu To Sang and Yu Shing Keung Memorial Fund Scholarship 2020/21 Miss Ling Rao, PhD candidate in Dr. Lydia Cheung’s lab, has been awarded the Yu To Sang and Yu Shing Keung Memorial Fund Scholarship 2020/21. 2021 ROHTO Award HK Mr. Siu Lun Michael Lai, PhD candidate in Dr. Raymond Chang’s Lab, has been awarded the Young Talent Award in The 2021 ROHTO Award HK.

RGC Research Fellow Scheme (RFS) 2021/22 - A grand total of HK$5,155,380 has been awarded to Dr. Stephanie Ma.

Outstanding Research Postgraduate Student 2019/20 Dr. Xinran Li, PhD graduate of Dr. Lydia Cheung’s Lab, has been awarded the Award for Outstanding Research Postgraduate Student 2019/20.

RGC General Research Fund (GRF) - A grand total of HK$17,161,871 has been awarded to Prof. Quan Hao, Prof. Jiandong Huang, Prof. Michael Huen, Prof. Pengtao Liu, Prof. Ren Sun, Prof. Julian Tanner, Dr. Martin Cheung, Dr. Stephanie Ma, Dr. Lydia Cheung, Dr. Bo Gao, Dr. Cora Lai, Dr. Chi Wai Lee, Dr. Jeff Ti, Dr. Cheng-Han Yu and Dr. Man Tong.

Li Ka Shing Prizes 2019/20 Miss Pit Shan Chong, MPhil graduate & PhD candidate in Dr. Lee Wei Lim’s Lab, has been awarded the Li Ka Shing Prize 2019/20.

RGC Early Career Scheme (ECS) - A grand total of HK$3,745,749 has been awarded to Dr. Mu He, Dr. Rubén Hervas Millan and Dr. Rio Sugimura.

RGC Theme-based Research Scheme (TRS) - A grand total of HK$42,278,000 has been awarded to Prof. Dong-Yan Jin.

Mary Sun Medical Scholarships 2020-21 Miss Sau Ni Ng, MPhil candidate in Dr. Lydia Cheung’s Lab, has been awarded the Mary Sun Medical Scholarship 2020-21.

National Natural Science Foundation (NSFC) – General Program - A grand total of RMB 580,000 has been awarded to Dr. Bo Gao.

National Natural Science Foundation (NSFC) – Young Scientist Fund - A grand total of RMB 230,000 has been awarded to Dr. Man Tong.

Recap of Events School Highlights

Jul 5 & 6, 2021 Single Cell Workshop

Jul 14, 2021 Research Chalk Talk by Dr. Mu He

Aug 26, 27, 30 & 31, 2021 RGC GRF/ECS Brainstorming Meeting- consultation meeting with Prof. Burkhard Becher, University of Zurich

Sep 1, 2021 BBMS Orientation

Sep 2 & 3, 2021 BBMS Summer Internship Poster Presentation

Sep 15, 2021 Research Chalk Talk by Dr. Rubén Hervas Millan

Jul 15, 22 & 29, 2021 HKU Distinguished Visiting Scholar Seminar Series by Prof. Lee Zou, Harvard Medical School; Prof. Andras Nagy, University of Toronto; and Prof. Samuel I. Stupp, Northwestern University

Jul 21, Sep 15 & 29, 2021 PDF Seminar

Aug 2-6, 2021 HKU Biomedical Sciences Summer Academy

Aug 16, 2021 Biochemistry Society Lab Tour

Aug 18, 2021 HKU Biomed Entrepreneurship Talk by Prof. Barbara Chan, HKU

Aug 23, 2021 HKUMed Academic Induction Talk

Aug 23 , 2021 RGC GRF/ECS 2022-23: Online Brainstorming Workshop- Zoom Lecture by Prof. Burkhard Becher, University of Zurich

Sep 20, 2021 Seminar on AI Innovation in Drug Discovery by Dr. Alex Zhavoronkov and Dr. Frank Pun, Insilico Medicine

Sep 23, 2021 Zoom Seminar by Prof. Hua Wang, The Ohio State University

Sep 24, 2021 Briefing Session for BBMS Summer Internship Programme by Dr. Stephanie Ma, Dr. Cheng-Han Yu & Dr. Masayo Kotaka

Sep 27, 2021 Teaching & Learning Chalk Talk by Dr. Kwok Ming Yao

Sep 30, 2021 Seminar Series on Human Embryonic Development, Stem Cells & Developmental Genomics by Dr. James Briscoe, The Francis Crick Institute

In the Media School Highlights

Jun 29, 2021 - Press Release: HKUMed identifies a new pathway to prevent invasive cell migration of cancer cells by blocking PI(3,4)P2 lipid synthesis and receptor recycling

Aug 25, 2021 - Press Release: HKUMed identifies an important gene linking the two hallmark pathological features: Amyloid β (A β ) plaques and neurofibrillary tangles (NFT) in Alzheimer’s disease (AD)

All Media Coverage

Aug 9, 2021 - Media Coverage: Prof. Michael Huen talks about mRNA vaccine and human DNA in an interview on Headline News

*Corresponding Authors | ^Current RPG Students Publications Highlights

1. Li X, Lau AY, Ng AS , Aldehaiman A, Zhou Y, Ng PK, Arold ST, Cheung LW* . Cancer-associated mutations in the p85 α N-terminal SH2 domain activate a spectrum of receptor tyrosine kinases. Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2101751118. 2. Lee TK, Guan XY, Ma S* . Cancer stem cells in hepatocellular carcinoma - from origin to clinical implications. Nat Rev Gastroenterol Hepatol. 2021 Sep 9. 3. Yeung SS^ , Ho YS, Chang RC* . The role of meningeal populations of type II innate lymphoid cells in modulating neuroinflammation in neurodegenerative diseases. Exp Mol Med. 2021 Sep 6. 4. Zhu X^, Fang H^, Gladysz K^, Barbour JA, Wong JW* . Overexpression of transposable elements is associated with immune evasion and poor outcome in colorectal cancer. Eur J Cancer. 2021 Sep 4;157:94-107. 5. Wang J, Feng D, Gao B* . An overview of potential therapeutic agents targeting WNT/PCP signaling. Handb Exp Pharmacol. 2021 Sep 1. 6. Tong M*, Wong TL , Zhao H, Zheng Y, Xie YN^, Li CH, Zhou L, Che N , Yun JP, Man K, Lee TK, Cai Z*, Ma S* . Loss of tyrosine catabolic enzyme HPD promotes glutamine anaplerosis through mTOR signaling in liver cancer. Cell Rep. 2021 Aug 24;36(8):109617. 7. Zhang Y, Zhang Y^ , Aman Y, Ng CT, Chau WH, Zhang Z, Yue M^ , Bohm C, Jia Y, Li S^ , Yuan Q, Griffin J, Chiu K, Wong DS , Wang B, Jin D , Rogaeva E, Fraser PE, Fang EF, St George-Hyslop P, Song YQ* . Amyloid- β toxicity modulates tau phosphorylation through the PAX6 signalling pathway. Brain. 2021 Aug 24:awab134. 8. Abulimiti A, Lai MS^, Chang RC* . Applications of adeno-associated virus vector-mediated gene delivery for neurodegenerative diseases and psychiatric diseases: Progress, advances, and challenges. Mech Ageing Dev. 2021 Aug 2;199:111549. 9. Uddin MS, Yu WS^, Lim LW* . Exploring ER stress response in cellular aging and neuroinflammation in Alzheimer's disease. Ageing Res Rev. 2021 Sep;70:101417. 10. Deng J , Zhang BZ, Chu H, Wang XL , Wang Y, Gong HR^, Li R , Yang D, Li C, Dou Y , Gao P, Cai JP, Jin M, Du Q, Chan JF, Kao RY, Yuen KY*, Huang JD* . Adenosine synthase A contributes to recurrent Staphylococcus aureus infection by dampening protective immunity. EBioMedicine. 2021 Jul 28;70:103505. 11. Jangra S, Bharti A, Lui WY^, Chaudhary V , Botelho MG, Yuen KS*, Jin DY* . Suppression of JAK-STAT signaling by Epstein-Barr virus tegument protein BGLF2 through recruitment of SHP1 phosphatase and promotion of STAT2 degradation. J Virol. 2021 Jul 28:JVI0102721. 12. Cheung CC*, Yang J, Tipoe GL . Multifactorial learning challenges in anatomy: What is the niche in current research? Anat Sci Educ. 2021 Jul 27. doi: 10.1002/ase.2125. 13. Fang X^, Ho JW* . FlowGrid enables fast clustering of very large single-cell RNA-seq data. Bioinformatics. 2021 Jul 20:btab521. 14. Cui D, Zhu Y, Yan D^ , Lee NP, Han L, Law S, Tsao GS, Cheung AL* . Dual inhibition of cMET and EGFR by microRNA-338-5p suppresses metastasis of esophageal squamous cell carcinoma. Carcinogenesis. 2021 Jul 16;42(7):995-1007. 15. Xie D, Chu H, Yang D, Ding Q, Huang G, Chen L, Cai Z*, Huang J* , Zhao Z*. A stark difference in the profiles of defective viral transcripts between SARS-CoV-2 and SARS-CoV. J Infect. 2021 Jul 1:S0163-4453(21)00315-7. 16. Lo Y^, Cheung YW, Wang L^, Lee M , Figueroa-Miranda G, Liang S, Mayer D, Tanner JA* . An electrochemical aptamer-based biosensor targeting Plasmodium falciparum histidine-rich protein II for malaria diagnosis. Biosens Bioelectron. 2021 Jun 30;192:113472. 17. Roy J^, Tsui KC^, Ng J, Fung ML, Lim LW* . Regulation of melatonin and neurotransmission in Alzheimer's disease. Int J Mol Sci. 2021 Jun 25;22(13):6841. 18. De Los Angeles A, Liu P* . Understanding totipotency: A role for alternative splicing. Dev Cell. 2021 Jun 21;56(12):1697-1699. 19. Mak VC, Li X, Rao L^, Zhou Y, Tsao SW, Cheung LW* . p85 β alters response to EGFR inhibitor in ovarian cancer through p38 MAPK-mediated regulation of DNA repair. Neoplasia. 2021 Jul;23(7):718-730.

New Faces School Highlights

Research Assistant Professor BSc (Newcastle University); PhD (University of Cambridge) Dr. Wong, Eric Tin Lok

Research Assistant Professor BS (Nankai U); PhD (HKU) Dr. Bao, Xiucong

In my PhD study and postdoctoral research, I focused on the development of chemical biological strategies to decipher the biological functions of histone post-translational modifications (PTMs) and their regulatory mechanisms. Now I am poised to combine state-of-the-art chemistry, biochemistry, biophysics, and cell biology approaches to solve the fundamental questions in immune response. Our overall mission is to elucidate the fundamental mechanisms responsible for carcinogenesis and to translate basic biomedical discovery into effective therapies for immune diseases. For anyone who wants to join my group, feel free to contact me baoxc@hku.hk.

During my PhD and postdoctoral training, I am fascinated by the diverse role of nutrients in health and disease of human, especially the complex metabolic rewiring in cancer. By utilising a multi-omics approach, my research focuses on identifying the nutrient preference of different subtypes of cancer, the key regulators for metabolic rewiring and the contribution of nutrients in cancer properties, such as cancer stemness and drug resistance. Our goal is to exploit the metabolic “weakness” of cancer to develop new treatment options and increase the efficiency of clinical drugs.

Upcoming Events

Oct 30, 2021 Information Day for UG Admissions

Oct 6, 2021 Briefing Session for BBMS Articulation Programme by Dr. Martin Cheung Oct 7, 2021 HKUMed Outreach Taster Lecture for St. Paul's Convent School by Dr. Joshua Ho & Dr. Jason Wong

Nov 3, 2021 HKU Biomed Entrepreneurship Talk Series

Oct 8, 2021 Career Talk by Biomedical Sciences Society

Oct 11, 2021 Orientation Session for Research Postgraduate Students

Oct 13 & 27 & Nov 10 & 24, 2021 PDF Seminar

Oct 21, 2021 Seminar Series on Human Embryonic Development, Stem Cells & Developmental Genomics by Prof. Joanna Wysocka, Stanford University

Nov 17, 2021 Chalk Talk by Dr. Chaogu Zheng, HKU

Nov 20, 2021 The 205th Congregation, HKUMed

Oct 22 & 29, 2021 RPG Seminar

Dec 8, 2021 Chalk Talk by Prof. Barbara Chan, HKU

Oct 27, 2021 Research Chalk Talk by Prof. Dong-Yan Jin

Dec 3, 2021 The 205 th Congregation, Faculty of Science

Upcoming Events

Oct 28, 2021 Teaching & Learning Chalk Talk by Dr. Masayo Kotaka

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