In the Media School Highlights
Jun 29, 2021 - Press Release: HKUMed identifies a new pathway to prevent invasive cell migration of cancer cells by blocking PI(3,4)P2 lipid synthesis and receptor recycling
Aug 25, 2021 - Press Release: HKUMed identifies an important gene linking the two hallmark pathological features: Amyloid β (A β ) plaques and neurofibrillary tangles (NFT) in Alzheimer’s disease (AD)
All Media Coverage
Aug 9, 2021 - Media Coverage: Prof. Michael Huen talks about mRNA vaccine and human DNA in an interview on Headline News
*Corresponding Authors | ^Current RPG Students Publications Highlights
1. Li X, Lau AY, Ng AS , Aldehaiman A, Zhou Y, Ng PK, Arold ST, Cheung LW* . Cancer-associated mutations in the p85 α N-terminal SH2 domain activate a spectrum of receptor tyrosine kinases. Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2101751118. 2. Lee TK, Guan XY, Ma S* . Cancer stem cells in hepatocellular carcinoma - from origin to clinical implications. Nat Rev Gastroenterol Hepatol. 2021 Sep 9. 3. Yeung SS^ , Ho YS, Chang RC* . The role of meningeal populations of type II innate lymphoid cells in modulating neuroinflammation in neurodegenerative diseases. Exp Mol Med. 2021 Sep 6. 4. Zhu X^, Fang H^, Gladysz K^, Barbour JA, Wong JW* . Overexpression of transposable elements is associated with immune evasion and poor outcome in colorectal cancer. Eur J Cancer. 2021 Sep 4;157:94-107. 5. Wang J, Feng D, Gao B* . An overview of potential therapeutic agents targeting WNT/PCP signaling. Handb Exp Pharmacol. 2021 Sep 1. 6. Tong M*, Wong TL , Zhao H, Zheng Y, Xie YN^, Li CH, Zhou L, Che N , Yun JP, Man K, Lee TK, Cai Z*, Ma S* . Loss of tyrosine catabolic enzyme HPD promotes glutamine anaplerosis through mTOR signaling in liver cancer. Cell Rep. 2021 Aug 24;36(8):109617. 7. Zhang Y, Zhang Y^ , Aman Y, Ng CT, Chau WH, Zhang Z, Yue M^ , Bohm C, Jia Y, Li S^ , Yuan Q, Griffin J, Chiu K, Wong DS , Wang B, Jin D , Rogaeva E, Fraser PE, Fang EF, St George-Hyslop P, Song YQ* . Amyloid- β toxicity modulates tau phosphorylation through the PAX6 signalling pathway. Brain. 2021 Aug 24:awab134. 8. Abulimiti A, Lai MS^, Chang RC* . Applications of adeno-associated virus vector-mediated gene delivery for neurodegenerative diseases and psychiatric diseases: Progress, advances, and challenges. Mech Ageing Dev. 2021 Aug 2;199:111549. 9. Uddin MS, Yu WS^, Lim LW* . Exploring ER stress response in cellular aging and neuroinflammation in Alzheimer's disease. Ageing Res Rev. 2021 Sep;70:101417. 10. Deng J , Zhang BZ, Chu H, Wang XL , Wang Y, Gong HR^, Li R , Yang D, Li C, Dou Y , Gao P, Cai JP, Jin M, Du Q, Chan JF, Kao RY, Yuen KY*, Huang JD* . Adenosine synthase A contributes to recurrent Staphylococcus aureus infection by dampening protective immunity. EBioMedicine. 2021 Jul 28;70:103505. 11. Jangra S, Bharti A, Lui WY^, Chaudhary V , Botelho MG, Yuen KS*, Jin DY* . Suppression of JAK-STAT signaling by Epstein-Barr virus tegument protein BGLF2 through recruitment of SHP1 phosphatase and promotion of STAT2 degradation. J Virol. 2021 Jul 28:JVI0102721. 12. Cheung CC*, Yang J, Tipoe GL . Multifactorial learning challenges in anatomy: What is the niche in current research? Anat Sci Educ. 2021 Jul 27. doi: 10.1002/ase.2125. 13. Fang X^, Ho JW* . FlowGrid enables fast clustering of very large single-cell RNA-seq data. Bioinformatics. 2021 Jul 20:btab521. 14. Cui D, Zhu Y, Yan D^ , Lee NP, Han L, Law S, Tsao GS, Cheung AL* . Dual inhibition of cMET and EGFR by microRNA-338-5p suppresses metastasis of esophageal squamous cell carcinoma. Carcinogenesis. 2021 Jul 16;42(7):995-1007. 15. Xie D, Chu H, Yang D, Ding Q, Huang G, Chen L, Cai Z*, Huang J* , Zhao Z*. A stark difference in the profiles of defective viral transcripts between SARS-CoV-2 and SARS-CoV. J Infect. 2021 Jul 1:S0163-4453(21)00315-7. 16. Lo Y^, Cheung YW, Wang L^, Lee M , Figueroa-Miranda G, Liang S, Mayer D, Tanner JA* . An electrochemical aptamer-based biosensor targeting Plasmodium falciparum histidine-rich protein II for malaria diagnosis. Biosens Bioelectron. 2021 Jun 30;192:113472. 17. Roy J^, Tsui KC^, Ng J, Fung ML, Lim LW* . Regulation of melatonin and neurotransmission in Alzheimer's disease. Int J Mol Sci. 2021 Jun 25;22(13):6841. 18. De Los Angeles A, Liu P* . Understanding totipotency: A role for alternative splicing. Dev Cell. 2021 Jun 21;56(12):1697-1699. 19. Mak VC, Li X, Rao L^, Zhou Y, Tsao SW, Cheung LW* . p85 β alters response to EGFR inhibitor in ovarian cancer through p38 MAPK-mediated regulation of DNA repair. Neoplasia. 2021 Jul;23(7):718-730.
Made with FlippingBook Digital Publishing Software