New Equipment School Highlights
Ultracentrifuge (Thermo Scientific/ WX100+)
Chemi doc system (Bio Rad/ ChemiDoc Imaging MP)
Ultrahigh speed centrifuge equipped with rotor T-865, max: 65,000rpm and rotor TH-641, max: 41,000rpm Location L4-05, Lab Block Tech-in-charge Mr. Leonard Cheung leonardc@hku.hk | +852-3917-9533
Chemiluminescence and fluorescence detection
Location L4-38, Lab Block
Tech-in-charge Ms. Molly Wong pfwong@hku.hk | +852-3917-9532
*Corresponding Authors | # Co-first Authors | School Members in Bold Publications Highlights
1. You R*, Ho YS, Chang RC *. The pathogenic effects of particulate matter on neurodegeneration: a review. J Biomed Sci. 2022 Feb 22;29(1):15. 2. Kwok AWC^, Qiao C, Huang R^ , Sham MH, Ho JWK, Huang Y* . MQuad enables clonal substructure discovery using single cell mitochondrial variants. Nat Commun. 2022 Mar 8;13(1):1205. 3. Zhou L, Ma S* . Deciphering cancer stem cells in liver cancers: New tools with improved resolution. Carcinogenesis. 2022 Mar 9:bgac028. doi: 10.1093/carcin/bgac028. 4. Roy J#^, Wong KY#, Aquili L, Uddin MS^, Boon CH, Tipoe GL, Wong KH, Fung ML, Lim LW* . Role of melatonin in Alzheimer's disease: From preclinical studies to novel melatonin-based therapies. Front Neuroendocrinol. 2022 Feb 12:100986. 5. Yu JH, Ma S* . Organoids as research models for hepatocellular carcinoma. Exp Cell Res. 2022 Feb 1;411(1):112987. 6. Xu Z, Wang L, Huan X, Lee H, Yang J, Zhou Z, Chen M, Hu S, Liu Y, Feng SP, Zhang T, Xu F, Chu Z* , Kim JT*. On-demand, direct printing of nanodiamonds at the quantum level. Adv Sci (Weinh). 2022 Feb;9(5):e2103598.1. 7. Du Y, Qian C* . Non-canonical bivalent H3K4me3K9me3 recognition by Spindlin1/C11orf84 complex. Bioessays. 2022 Jan 29:e2100229. 8. Chen P# , Tan Z#*, Shek HT, Zhang JN , Zhou Y, Yin S, Dong Z, Xu J, Qiu A, Dong L, Gao B* , To MK*. Phenotypic spectrum and molecular basis in a Chinese cohort of osteogenesis imperfecta with mutations in type I collagen. Front Genet. 2022 Jan 28;13:816078. 9. Hu F^, Fong KO, Cheung MP , Liu JA, Liang R, Li TW , Sharma R, Ip PP, Yang X, Cheung M* . DEPDC1B promotes melanoma angiogenesis and metastasis through sequestration of ubiquitin ligase CDC16 to stabilize secreted SCUBE3. Adv Sci (Weinh). 2022 Jan 27:e2105226. 10. Cheng Y*, Kang XZ^, Cheng T^ , Ye ZW, Tipoe GL, Yu CH , Wong CM, Liu B, Chan CP, Jin DY* . FACI is a novel CREB-H-induced protein that inhibits intestinal lipid absorption and reverses diet-induced obesity. Cell Mol Gastroenterol Hepatol. 2022 Jan 27:S2352-345X(22)00017-0. 11. Strekalova T*, Liu Y^ , Kiselev D, Khairuddin S, Chiu JL , Lam J, Chan YS , Pavlov D, Proshin A, Lesch KP, Anthony DC, Lim LW* . Chronic mild stress paradigm as a rat model of depression: facts, artifacts, and future perspectives. Psychopharmacology (Berl). 2022 Jan 24:1–31. 12. Yuen CT#, Thean DG#, Chan BK#^, Zhou P#, Kwok CC#, Chu HY, Cheung MS, Wang B^ , Chan YM, Mak SY, Leung AY, Choi GC , Zheng Z, Wong AS* . High-fidelity KKH variant of Staphylococcus aureus Cas9 nucleases with improved base mismatch discrimination. Nucleic Acids Res. 2022 Jan 21:gkab1291. 13. Wong KH* , Nam HY, Lew SY, Naidu M, David P, Kamalden TA, Hadie SN, Lim LW* . Discovering the potential of natural antioxidants in age-related macular aegeneration: A review. Pharmaceuticals (Basel). 2022 Jan 14;15(1):101. 14. Chan CP, Jin DY* . Cytoplasmic RNA sensors and their interplay with RNA-binding partners in innate antiviral response: Theme and variations. RNA. 2022 Jan 14:rna.079016.121. 15. Liu M^, Wang L^, Lo Y^, Shiu SC, Kinghorn AB, Tanner JA* . Aptamer-enabled nanomaterials for therapeutics, drug targeting and imaging. Cells. 2022 Jan 4;11(1):159. 16. Li C#, Ye Z#, Zhang AJ#, Chan JF#, Song W, Liu F, Chen Y, Kwan MY, Lee AC, Zhao Y, Wong BH, Yip CC, Cai JP, Lung DC, Sridhar S, Jin D , Chu H, To KK, Yuen KY*. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections by intranasal or testicular inoculation induces testicular damage preventable by vaccination in golden Syrian hamsters. Clin Infect Dis. 2022 Feb 18:ciac142. 17. Long JT, Leinroth A, Liao Y, Ren Y, Mirando AJ, Nguyen T, Guo W, Sharma D, Rouse D, Wu C, Cheah KS , Karner CM, Hilton MJ*. Hypertrophic chondrocytes serve as a reservoir for marrow associated skeletal stem and progenitor cells, osteoblasts, and adipocytes during skeletal development. Elife. 2022 Feb 18;11:e76932. 18. Chow CF#, Guo X#, Asthana P#, Zhang S, Wong SK , Fallah S, Che S, Gurung S, Wang Z, Lee KB, Ge X, Yuan S, Xu H, Ip JP, Jiang Z , Zhai L, Wu J, Zhang Y, Mahato AK, Saarma M, Lin CY, Kwan HY, Huang T, Lyu A, Zhou Z , Bian ZX*, Wong HL*. Body weight regulation via MT1-MMP-mediated cleavage of GFRAL. Nat Metab. 2022 Feb 17. 19. Shuai H, Chan JF, Hu B, Chai Y, Yuen TT, Yin F, Huang X, Yoon C, Hu JC, Liu H, Shi J, Liu Y, Zhu T, Zhang J, Hou Y, Wang Y, Lu L, Cai JP, Zhang AJ, Zhou J, Yuan S, Brindley MA, Zhang BZ, Huang JD , To KK, Yuen KY*, Chu H*. Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 Omicron. Nature. 2022 Jan 21.
Made with FlippingBook - Online Brochure Maker