School Highlights
New Equipment
We continuously purchase and install new equipment to facilitate our research and innovation, and we’re happy to introduce the following new members of our equipment family:
Hybridization Oven (ACD/HybEZII System)
Gene Pulser(Biorad/ GenePulserXcellTotal System) Electroporation system for transfection of mammalian cells, bacteria & fungi Location: L4-06, Lab Block Tech-in-charge: Mr. Leonard Cheung leonardc@hku.hk | +852-3917-6832
Gasket-sealed, temperature-controlled benchtop hybridization oven for 20 slides
Location: L4-01, Lab Block Tech-in-charge: Ms. Kary Xu karyxu@hku.hk | +852-3917-9268
Sonifier(Emerson/SFX550) Ultrasonic homogenizer system for liquid processing from 0.2 to 1000ml
Location: L4-03, Lab Block Tech-in-charge: Ms. Sandra Wong syywong@hku.hk | +852-3917-6926
Publication Highlights *Co-corresponding Authors
Guo W, Kinghorn AB , Zhang Y, Li Q, Poonam AD, Tanner JA *, Shum HC*. Non-associative phase separation in an evaporating droplet as a model for prebiotic compartmentalization. Nat Commun. 2021 May 27;12(1):3194. Zhang T, Pramanik G, Zhang K, Gulka M, Wang L, Jing J, Xu F, Li Z, Wei Q, Cigler P*, Chu Z *. Toward Quantitative Bio-sensing with Nitrogen-VacancyCenterin Diamond. ACS Sens. 2021 May 26. doi:10.1021/acssensors.1c00415. Yu J, Oentaryo MJ, Lee CW . Local protein synthesis of neuronal MT1-MMPforagrin-induced presynaptic development. Development. 2021 May15;148(10):dev199000. Feng D, Wang J, Yang W , Li J, Lin X, Zha F, Wang X, Ma L, Choi NT , Mii Y, Takada S, Huen MS , Guo Y, Zhang L, Gao B . Regulation of Wnt/PCP signaling through p97/VCP-KBTBD7-mediated Vangl ubiquitination and endoplasmic reticulum-associated degradation. Sci Adv. 2021 May14;7(20):eabg2099. Feng Z, Yu CH . PI(3,4)P2-mediated membrane tubulation promotes integrin trafficking and invasive cell migration. Proc Natl Acad Sci USA. 2021 May11;118(19):e2017645118. Huang X, Huang Y . Cellsnp-lite: an efficient tool for genotyping single cells. Bioinformatics. 2021 May 8:btab358. Lin Q, Rong L , Jia X, Li R, Yu B , Hu J, Luo X, Badea SR, Xu C , Fu G, Lai K, Lee MC , Zhang B, Gong H , Zhou N, Chen XL, Lin SH*, Fu G*, Huang JD *. IFN- γ -dependent NK cell activation is essential to metastasis suppression by engineered Salmonella. Nat Commun. 2021 May 5;12(1):2537. Tan SZ, Poon CH, Chan YS, Lim LW . Prelimbic Cortical Stimulation Disrupts Fear Memory Consolidation through Ventral Hippocampal Dopamine 2 Receptors. Br J Pharmacol. 2021 Apr 26. doi: 10.1111/bph.15505. Loong JH, Wong TL, Tong M , Sharma R, Zhou L, Ng KY, Yu HJ, Li CH , Man K, Lo CM, Guan XY, Lee TK, Yun JP, Ma S . Glucose deprivation induced aberrant FUT1-mediated fucosylation drives cancer stemness in hepatocellular carcinoma. J Clin Invest. 2021 Apr 20:143377. Chan A, Ma S , Pearson BJ, Chan D . Collagen IV differentially regulates planarian stem cell potency and lineage progression. Proc Natl Acad Sci U S A. 2021 Apr 20;118(16):e2021251118. Zhao L, Gao X , Zheng Y, Wang Z, Zhao G, Ren J, Zhang J, Wu J , Wu B, Chen Y, Sun W, Li Y, Su J, Ding Y, Gao Y, Liu M, Bai X, Sun L, Cao G, Tang F, Bao S, Liu P *, Li X*. Establishment of bovine expanded potential stem cells. Proc Natl Acad Sci USA. 2021 Apr 13;118(15):e2018505118. Buang N, Tapeng L, Gray V , Sardini A, Whilding C, Lightstone L, Cairns TD, Pickering MC, Behmoaras J, Ling GS *, Botto M*. Type I interferons affect the metabolic fitness of CD8+ T cells from patients with systemic lupus erythematosus. Nat Commun. 2021 Mar 31;12(1):1980.
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