Intensive Care Unit (ICU) research
Key 2020 ED research projects include: › The creation of an Emergency Department Airway Registry: a multicentre observational trial into the procedure of ED intubation. This ongoing data collection into its sixth year and is now the world’s largest airway database › Use of High-Risk Influenza Stratification Test (HIST) in patients with suspected influenza infection: a multi-centre study that utilises a blood-based test to stratify patients with suspected influenza into low- and high-risk groups for developing severe disease › Nurse Initiated Fascial Iliacus Block (FIB) Study: is a prospective randomised control trial reviewing the implementation, timeliness and efficacy of early Nurse Initiated FIB compared to standard medically instigated FIB › Hypertensive emergencies: a systematic review that will generate an NSLHD guideline for hypertensive crises › A systematic review of emergency physician limited point compression ultrasound to diagnose proximal deep venous thrombosis › The PACE Study: an NHMRC-funded study reviewing the impact of an intensive multi-modal intervention program for patients presenting to ED with lower back, knee and neck pain Publication highlights include: › Groves CP, Butland BK, Atkinson RW, Delaney AP, Pilcher DV. Intensive care admissions and outcomes associated with short-term exposure to ambient air pollution: a time series analysis. Intensive Care Med . Jun 2020;46(6):1213-1221. doi:10.1007/ s00134-020-06052-z › Litton E, Bass F, Dickson C, et al. Prophylactic Intra-Aortic Balloon Counterpulsation in High Risk Cardiac Surgery: The PINBALL Pilot Multicentre, Registry-Linked, Randomised, Controlled Feasibility Trial. Heart Lung Circ . May 2020;29(5):710-718. doi:10.1016/j.hlc.2019.04.006
ICU research at NSLHD includes investigator-initiated, collaborative group, and industry-sponsored studies. Our ICU researchers have strong partnerships with many leading Australian and international research institutions, including The George Institute for Global Health (UNSW, Sydney), ANZCIS Research Centre (Monash University), Brain and Mind Centre (University of Sydney), Macquarie University, and the Canadian Critical Care Trials Group. The RNSH ICU research group has a strong history of supporting staff through higher degree research programs; several staff have been awarded research degrees by thesis as an extension of registrar research projects, and the group is currently supporting seven PhD candidates. At RNSH, ICU research is supported via a research education program with regular registrar teaching on evidence-based medicine, a monthly journal club, and the provision of a clinical research course. This provides an excellent support structure for trainees completing their professional college projects. › Luethi N, Bailey M, Higgins A, et al. Gender differences in mortality and quality of life after septic shock: A post-hoc analysis of the ARISE study. J Crit Care . Feb 2020;55:177-183. doi:10.1016/j.jcrc.2019.11.002 › Mackle D, Bellomo R, Bailey M, et al. Conservative Oxygen Therapy during Mechanical Ventilation in the ICU. N Engl J Med . Mar 12 2020;382(11):989- 998. doi:10.1056/NEJMoa1903297 › Narayan SW, Castelino R, Hammond N, Patanwala AE. Effect of mannitol plus hypertonic saline combination versus hypertonic saline monotherapy on acute kidney injury after traumatic brain injury. J Crit Care . Jun 2020;57:220-224. doi:10.1016/j. jcrc.2020.03.006
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