Diabetes Research
Publication highlights include: › Brendon L. Neuen, Toshiaki Ohkuma, Bruce Neal, David R. Matthews, Dick de Zeeuw, Kenneth W. Mahaffey, Greg Fulcher, Jaime Blais, Qiang Li, Meg J. Jardine, Vlado Perkovic, David C. Wheeler, Relative and Absolute Risk Reductions in Cardiovascular and Kidney Outcomes With Canagliflozin Across -KDIGO Risk Categories: Findings From the CANVAS Program. Am J Kidney Disease 2020 › Glastras SJ, Cohen N, Dover T, Kilov G, Macisaac RJ, McGill M, Fulcher GR. The Clinical Role of Insulin Degludec/lnsulin Aspart in Type 2 Diabetes: An Empirical Perspective from Experience in Australia. J Clin Med. 2020 Apr 11;9(4):1091. doi: 10.3390/jcm9041091 › Mehta R, Chen R, Hirose T, Matthew J, Kok A, Lehmann R, Unnikrishnan AG, Yavuz DG, Fulcher G. Practical use of insulin degludec/insulin aspart in a multinational setting: Beyond the guidelines. Diabetes Obes Metab. 2020; 1-15 › Natassia Rodrigo, Sarah J. Glastras. Pathophysiology Underpinning Gestational Diabetes Mellitus and the Role of Biomarkers for its Prediction. EMJ . 2020; DOl/10.33590/ emj/19-00150 › Victoria L. Rudland, Sarah A.L. Price, Ruth Hughes, Helen L. Barrett, Janet Lagstrom, Cynthia Porter, Fiona L. Britten, Sarah Glastras, Ian Fulcher, Peter Wein, David Simmons, H. DavidMcIntyre. Leonie Callaway. ADIPS 2020 guideline for pre-existing diabetes and pregnancy. Aust N Z J Obstet Gynaecol 2020; 60: E18-E52
The diabetes research group includes basic and clinical research activities. Basic research is led by Associate Professor Sarah Glastras, who has a major interest in maternal factors that influence pregnancy outcomes; her expertise in this field has led to the publication of reviews and guidelines. Lab-based research involves epigenetic changes (how behaviours and environment can cause changes that the way genes work) while clinical research has focused on diabetes complications, obesity and the impact of diabetes on both pregnancy and resultant offspring. Diabetes education unit is currently planning audits of a novel way to optimise insulin management; and a new approach to integrated care for diabetes management. The NSLHD Diabetes Network has also focused on new therapies, diabetes complications, obesity and the impact of diabetes on both pregnancy and the resultant offspring. Integrated care for patients with diabetes and renal disease as co-existing conditions has been the focus of several important collaborations. The COVID-19 pandemic has also driven research projects in both renal medicine and diabetes and the activities of the clinical trial group in diabetes has been associated with recent publications.
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