Pain Management The Pain Management Research Institute (PMRI) is a recognised research centre and clinical facility of NSLHD and the Faculty of Medicine and Health at the University of Sydney. The PMRI includes 38 academic and 11 professional staff who focus on research and education, with research led by more than a dozen staff members. Our pain department, via the PMRI, conducts a wide range of clinical trial activity and other research projects, with a focus on chronic pain that has both a biological (neuroscientific) and aversive (emotional) experience. Research streams include pain pathways, cancer survivor pain, trials of new therapies, brain behaviour and society, and social aspects of pain. NHMRC grant to determine whether neuromodulation of brain rhythms can FUNDING HIGHLIGHTS FOR THE RENAL GROUP INCLUDE: $1.6m $1.0m relieve chronic pain. Australian Department of Health grant for pain education for health professionals: enhancing knowledge and competency in community-based pain management. $2.99m NHMRC grant to determine the role of neural and non-neural factors in preventing the transition from acute to chronic pain. $2.99m
Publication highlights include: › Karos Kai, McParland J L Bunzli S, Devan, H, Hirsh A, Kapos F, Heogh W, Moore D, Tracy L, Ashton James C. The Social threats of COVID19 for people with Chronic Pain. Pain 2020;161(10):2229-35 › Konen, L.M., Winters BL, Vaughan C. Opioid presynaptic disinhibition of the midbrain periaqueductal grey descending analgesic pathway. British Journal of Pharmacology. 2020;177:2320-32 › Konen, L.M., Vaughan, C. A newmouse line with reduced GluA2 Q/R site RNA editing exhibits loss of dendritic spines, hippocampal CA1- neuron loss, learning and memory impairments and NMDA receptor-independent seizure vulnerability. Molecular Brain. 2020;13:27 › Sharpe, L. Emma Jones, Claire Ashton-James, Nicholas M K, Katheryn Refshauge. Necessary components of psychological treatment in pain management programs: A Delphi study. European Journal of Pain. 2020;24:1160-8
› Tauben DJ, Langford DJ, Sturgeon JA, Rundell SD, Towle C, Bockman C,
Nicholas M. Optimizing telehealth pain care after COVID-19. Pain. 2020 Nov;161(11):2437-2445. doi: 10.1097/j. pain.0000000000002048. PMID: 32826752; PMCID: PMC7566302
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