The team received about $2 million in research funding in 2020.
Prof Sue Kurrie
CurranAgeing ResearchUnit
Publication highlights include: › Lo SY, Zhang M, Hubbard RE, Gnjidic D, RedstonMR, Hilmer SN. Development and validation of a frailty index based on data routinely collected across multiple domains in NSWhospitals. Australas J Ageing. 2021 Jun;40(2):184-194. doi: 10.1111/ajag.12888. Epub 2020 Dec 19. PMID: 33340206 › Mach J, Gemikonakli G, Logan C, Vander Wyk B, Allore H, Ekambareshwar S, Kane AE, Howlett SE, de Cabo R, Le Couteur DG, Hilmer SN. Chronic Polypharmacy with Increasing Drug Burden Index Exacerbates Frailty and Impairs Physical Function, with Effects Attenuated by Deprescribing, in Aged Mice. J Gerontol A Biol Sci Med Sci. 2021May 22;76(6):1010-1018. doi: 10.1093/gerona/glaa060. PMID: 32147704; PMCID: PMC8140051 Publication highlights include: › Nguyen TA, Pham T, Dang TH, HintonWL, Nguyen AT, Pham TL, Crotty M, Kurrle S, Bui QT, Nguyen H, Roughead EE. Towards the development of Vietnam’s national dementia plan-the first step of action. Australas J Ageing 2020 Jun; 39(2): 137-141 › Walker P, Kifley A, Kurrle S, Cameron ID. Increasing the uptake of vitamin D supplement use in Australian residential aged care facilities: results from the vitamin D implementation (ViDAus) study. BMC Geriatr. 2020 Oct 6;20(1):383
The Curran Ageing Research Unit at Hornsby Ku-ring-gai Hospital went from strength to strength in 2020. One of the Unit’s research highlights was beginning work on a randomised trial of the frailty translational study, the NHMRC-funded Frailty Screening and Management Study (FORTRESS). This involved working with the Northern Sydney Primary Health Network to develop intervention and links with primary healthcare services. The group also continued participation in dementia clinical drug trials with further trials to commence in late 2020 or early 2021. The group also began work on intergenerational care program of research looking at barriers and enablers to play group participation in residential aged care facilities. This last project was courtesy of generous philanthropic funding received by the unit.
Penney Ageing Research Unit The Penney Ageing Research Unit at RNSH supports a number of PhD students and academics. In recent years, the group has focused on
John Mach and Sarah Hilmer
optimising medication management in frail older patients . In particular, it has developed validated tools for medication review based on the Drug Burden Index, which are now available in routine clinical care. With an interest in optimising medication review for older people in the community, the group has developed a system called Goal-directed Medication review Electronic Decision Support System (G-MEDSS) © which helps to provide clinical decision support for healthcare practitioners conducting medical reviews for older patients, to tailor care to meet their goals and preferences. Finally, the group has an interest in understanding the causation and mechanisms of relationships between high Drug Burden Index, frailty and functional impairment.
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