Ardmac Life Sciences

Life Sciences. Our clients work at the forefront of innovation. www.ardmac.com

Life Sciences. Our clients work at the forefront of innovation. PHARMA MEDTECH HEALTHCARE MICROELECTRONICS Protecting Life.

Our clients work at the forefront of innovation. Protec Life. For almost 50 years Ardmac has been delivering controlled environments to customers in the life sciences and advanced manufacturing sectors. 04. About Ardmac 10 . Design & Build 14. Architectural 16. Off Site Manufacturing 18. Microelectronics 20. Safety First 22. Expert Teams 24. Working Smart 28. Innovation 30. Sustainability 34. Case Studies 50. Contact Us

ABOUT ARDMAC

cting Our innovative cleanroom solutions are built on trust, collaboration and technical expertise. Design and Build Architectural Off Site Manufacturing

Ardmac is one of Europe’s leading cleanroom providers, delivering high-quality solutions for the world’s top pharmaceutical manufacturers, the largest semiconductor producer, and numerous medical device companies and healthcare providers. Modern manufacturing cleanrooms must meet increasing demands for standardisation, rapid deployment, and accelerated schedules. The rise of single-use systems (SUS) and proof of closure has become a key driver in facility and process design. To address these evolving requirements, modern cleanroom facilities must be designed with standardisation, flexibility, and adaptability in mind. They should allow for rapid deployment and easy reconfiguration to accommodate changing processes and accelerated project timelines.

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EASILY RECONFIGURED

ADAPTABLE

STANDARDISED

FLEXIBLE

“Across all the industries we work in, we’re consistently delivering innovative new product and service offerings. Our clients are at the forefront of global innovation, so we need to be at the forefront of what’s technologically and operationally possible to meet their needs.” Enda Murphy, Chief Business Officer

ABOUT ARDMAC

1 . 2M Global manufacturing space in square feet 250 K 250,000m² cleanroom space built in 3 years 358 + 358MW data centre capacity built in 3 years 529 + Ardmac Staff Manufacturing facilities across Europe & the USA 8 RoSPA Gold winners for Health & Safety 25

Delivering Cleanroom Excellence Across Europe and Beyond.

Austria Belgium Denmark

Finland France Germany Ireland Italy Morocco Poland Portugal Singapore Spain United Kingdom USA

At Ardmac, our commitment to delivering world-class cleanroom environments has taken us across Europe and around the globe. With almost 50 years of experience serving the life sciences sector, we have earned the trust of leading pharmaceutical, biotech, and medical device clients through consistent delivery of high-performance, regulatory- compliant facilities — wherever they are needed. From large-scale biopharma campuses in Ireland and modular CDMO installations in Denmark, to precision built medical device cleanrooms in the UK and ongoing, live projects throughout mainland Europe, Ardmac’s cleanroom solutions are built to meet the most demanding technical and operational standards. Our value is not just visible on the projects we deliver. It is embodied by the people that represent Ardmac around the globe, experienced teams who understand local markets, regulations, and the urgency that defines the life sciences industry.

Our cleanroom reach is truly global, but our delivery is always local.

Our vision is to be the contractor of choice for clients and the workplace of choice for great people.

At Ardmac, our reputation is built on delivering results and exceeding client expectations. For almost 50 years, we have grown from a small Irish operation to the leading provider of high-tech cleanrooms, data centre solutions, EV battery & microelectronic facilities, quality fit-outs, specialised refurbishments, and turnkey construction of manufacturing facilities across Europe. We believe in setting new standards for our industry and driving innovation, we believe in tailoring solutions to our clients’ evolving needs, and in working hard to harness our unrivalled knowledge to deliver safety first and excellence as standard across award winning projects.

For our clients, that means acting with honesty and integrity always. Respect always and an open and transparent approach are key to developing long- lasting, trusting relationships. For our employees, that means encouraging them to be forward-thinking, to embrace change, and to share new ideas and knowledge. That experience and knowledge feeds back into projects to bring certainty to our clients, and to deliver superior results. Ultimately, we settle for nothing less than excellence as standard . We go the extra mile to ensure that we continue to lead the way in our industry and to uphold our ethos of Building Better.

ABOUT ARDMAC

Our Guiding Principles.

01. Safety First.

04. Excellence as Standard.

Safety first and always is foremost in our thinking. For everyone around us, in everything we do and wherever we impact.

Excellence is the certainty that we bring to our projects. We need to plan intelligently, think smart, and deliver wholeheartedly. So we go the extra mile, to be the best. 05. Deliver our Brand Promise. We all play our part in re-enforcing Ardmac’s enviable reputation by focusing on the client’s needs and taking pride in our work. We Build Better together.

02. Understand our Customers. Listen to the client, understand their

project vision and focus on the result. Build relationships - they matter. Ensure a positive experience so that our customers come back to us time and time again.

03. Respect Always.

We are open, honest, and transparent with each other to enable us to achieve the same goal.

Design and Build: Single source solution, integrating architectural envelopes with mechanical, electrical, and process systems.

Ardmac specialises in the design and construction of turnkey solutions for controlled environments across the Pharmaceutical, Biotechnology, Medical Devices, and Advanced Manufacturing industries. Following the concept design phase of any project, a detailed design must be completed before construction can begin—especially when opting for a design and build procurement route. Ardmac offers a single-source work package, assuming full responsibility for the design and construction of the project. Under a single contract, we manage safety, cost, schedule, and quality, ensuring the cleanroom’s performance meets the highest standards. We guarantee compliance with critical performance criteria, including:

At Ardmac, we take pride in our collaborative approach, working closely with clients to transform initial concepts into commissioned and certified controlled environments. Our team of experienced cleanroom designers and engineers supports clients from the initial concept through detailed design, addressing unique site challenges and ensuring full compliance with local codes and regulatory requirements. A full Turnkey Design & Build Cleanroom project begins with a Pre-Construction Services Agreement (PCSA). This agreement fosters a collaborative approach, allowing Ardmac to provide expert guidance at an earlier stage of the project life cycle, ensuring the efficient and successful delivery of controlled environments.

• Particulate Concentration • Room Pressurisation • Temperature & Humidity Control

• Containment Measures • Illumination Standards

DESIGN AND BUILD

Design.

Manufacture.

Build.

Benefits of a PCSA approach for delivery of design & build turnkey cleanroom facilities.

DESIGN AND BUILD

01. Expertise and Experience: Ardmac has extensive experience in designing and constructing cleanrooms for various industries such as pharmaceuticals, medtech, microelectronics and healthcare. We ensure that our cleanrooms are built to the highest standards and in compliance with relevant regulations and industry guidelines. 02. Customised Solutions: Ardmac works closely with clients to understand their specific requirements and preferences. We can tailor the cleanroom design to meet the unique needs of each client, including size, layout, cleanliness level, HVAC system, and equipment integration. 03. Turnkey Solution: Ardmac provides a complete turnkey solution, handling all aspects of the cleanroom project from design and construction to installation and commissioning. This minimises the client’s involvement and ensures a seamless and efficient process from start to finish. 04. Quality Assurance: Ardmac is committed to delivering high-quality cleanroom facilities that meet or exceed client expectations. We use quality materials and construction techniques to ensure the durability, reliability, and functionality of the cleanroom over the long term.

05. Compliance and Validation: Ardmac ensures that the cleanroom meets all relevant regulatory requirements and industry standards, such as ISO cleanroom classifications, GMP guidelines, and FDA regulations. We also provide validation services to verify the performance and cleanliness of the cleanroom before handover to the client. 06. Project Management: Ardmac assigns a dedicated project manager to oversee all aspects of the cleanroom project, including scheduling, budgeting, subcontractor management, and quality control. This ensures that the project is completed on time, within budget, and to the highest quality standards. 07. Single Point of Contact: By choosing Ardmac for the cleanroom project, clients have a single point of contact for all their needs, simplifying communication and streamlining the project management process. Overall, partnering with Ardmac to build a turnkey cleanroom offers clients peace of mind, expertise, customisation, and a high-quality facility that meets their specific requirements and regulatory standards.

Architectural: Modular, pre-engineered Cleanroom systems with flexibility designed in.

Our range of architectural solutions when combined provide the most advanced and aesthetically pleasing compliant cleanrooms. Walls, ceilings, doors and floors integrate seamlessly with GMP detailing to provide an airtight performance envelope. We leverage industry leaders as partners to provide integrated Terminal HEPA Housings, return air solutions and lighting specific to, and integrated in, our cleanroom systems. There has been a significant shift from open manufacturing systems to a more closed-system approach where the validated closed-system allows for a loosening of cleanroom classifications and a shift in cleanroom design to open ballroom or segregated matrix of suites.

Today’s rapid deployment and reduced schedules are all drivers for the modern manufacturing cleanroom facility. The continued deployment of single-use systems (SUS) coupled with proof of closure has become a key driver for facility and processes design that embrace the need for the next generation cleanrooms that are standardised, flexible, adaptable and easily reconfigured. requirement for standardisation,

Ardmac cGMP envelope protects your people, products and process, creating a safe and sterile environment that will exceed industry requirements.

Walkable ceiling systems Twin cassette ceilings

Lighting

Modular wiring

Cleanroom wall panels

Glass walls

Bi-panel partitions

Flush doors

Return airwalls

Bumper walls

HEPA filtration

ARCHITECTURAL

OFF SITE MANUFACTURING

Off Site Manufacturing: Ardmac controlled environment solutions.

Benefits of Ardmac’s Modular Approach

Ardmac has extensive expertise in designing production spaces for critical environments, recognising our clients’ growing need for speed to market. Our off site building solutions are tailored to meet the unique demands of the life sciences, data center, and advanced manufacturing industries. Our modular solutions offer unmatched flexibility, allowing for easy expansion or modification as business needs evolve. Designed with a comprehensive approach, we consider all aspects of the build, from architectural aesthetics to mechanical, electrical, and process services, ensuring seamless integration for each application.

• Fast & Efficient Turnaround – Predictable timelines with a streamlined process. • Scalability & Adaptability – Easily repurpose or expand modular units. • Portability – Units can be transported to other locations as needed. • Safer Work Environment – Reduced on-site noise, dust, and disruption. With eight global manufacturing sites, Ardmac produces purpose-built modular units to the highest industry standards. Off site manufacturing minimizes on-site disruptions, enhancing safety and efficiency. Each module undergoes rigorous testing at our manufacturing facility before shipping, ensuring full compliance. Once installed and connected to permanent utilities, the units are retested on-site, guaranteeing swift compliance and operational readiness.

Delivering quality, safety, and schedule confidence every time. Build smarter and faster with off-site modular construction: streamlined, sustainable, scalable, and operational-ready.

Hot and cold aisle containment

Advanced therapies

Cold Rooms

Turnkey cleanrooms

Operating theatres

Mobile laboratories

Diagnostics

Biosafety BSL 2 & BSL 3

QA/ QC LABS

GMP manufacturing suites finish

Isolation suites

Mission Critical: Cleanrooms, mini-environments and tool install.

Our objective is to create a safe and precision- controlled particle free clean environment that exceeds industry requirements of low off-gassing, vibration sensitivity and compatibility. Our experience in cleanroom construction has allowed us to develop specialised knowledge and skills that enable us to deliver projects that meet the specific needs of the microelectronics industry. we, at Ardmac pride ourselves on understanding the unique demands of the Microelectronics and related Advanced Technology Facilities (ATF), as well as their critical supply chain vendors and partners. Nothing less is acceptable for today’s fast evolving manufacturing challenges and mission critical facilities. Safe and precision controlled particle free clean environment.

Ardmac has been one of the largest providers of microelectronics Cleanrooms, mini-environments and tool install packages throughout Europe. We have worked with the top wafer fab and microelectronics manufacturers, along with their key vendor supply chain partners during this time. With our expertise in cleanroom construction, we can provide a controlled environment that meets the strict standards of the microelectronics industry. As consumers, we demand ever increasing performance, coupled with reliability. This creates a challenge of speed to market, then to volume and finally flexibility and change. We leverage technology and industry partners in the delivery of the complete solution, allowing our customers to focus on their core business.

MICROELECTRONICS

Safety First. We will never compromise on safety.

“We have successfully embedded safety into the very core of Ardmac’s identity. It sets the tone for everything we do, everywhere we do it.” Jason Casey, Chief Operations Officer

Ardmac will never compromise on safety. It’s not just a priority, its our number one guiding principle. Our approach to safety goes far beyond compliance, shaping the way we think, act, and deliver across all our projects. As we continue to grow and expand into new markets, our unwavering commitment to safety remains at the forefront of our work. It is the tool for ensuring the wellbeing of our people, our clients, and the communities we serve. A safety standard that sets us apart Ardmac’s commitment to safety is best reflected in our strong track record for safety performance. However, for us, safety isn’t just about statistics, it’s about our people. We have successfully embedded safety into every level of our organisation, creating an open and honest environment where all voices are heard. Through analysis of our comprehensive safety metrics, we know the impact we are having in this area. We believe this is a clear indicator of the proactive safety culture Ardmac has built. Our clients trust us to deliver their vision but doing so safely is their key priority. We are proud to commit to accepting nothing less than 100% safe, whenever and wherever we work.

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SAFETY FIRST

93.5% Annual employee satisfaction survey

EXPERT TEAMS

Expert Teams: A culture of respect that fosters a passion for excellence.

Our people are our greatest asset. As a business, Ardmac is incredibly proud of the dynamic, forward- thinking culture we have built, and we recognise our employees as the driving force behind our success. Their passion, dedication, and commitment to excellence are evident in everything we do, every single day. We continue to invest in enabling our people to thrive in a supportive and inclusive culture and we know that our concerted efforts to achieve this are working because our people tell us. We were delighted to achieve a satisfaction index score of 93.5% in our annual employee satisfaction survey. For us, this is a strong validation of the impact of our people-first approach. It also informs our future efforts to ensure that Ardmac continues to be a place where people feel respected, rewarded, and recognised for their commitment to delivering our clients’ vision. A Commitment to Development Our clients are building the future so ensuring Ardmac’s people are at the forefront of developing sector expertise is incredibly important to our business. We recognise the essential role played by investing in learning and development. We consider investing in our people as an investment in our success. Our leadership team plays a key role in this and proactively ensures that our comprehensive learning and development framework is implemented across our entire organisation. We believe that through supporting the growth and development of our employees, we are maintaining and enhancing Ardmac’s reputation for quality and technical expertise. We are committed to equipping our people with the skills and knowledge they need to meet our clients existing and future requirements. Through strong partnerships with institutions like Trinity College Dublin and the Irish Management Institute, along with our dedicated panel of coaches and mentors, Ardmac continues to support our people to enjoy meaningful, long-term careers where they can reach their full potential.

The number of people on the Ardmac team for more than 10 years

A Culture of Respect Respect is a core Ardmac principle and is evident in every aspect of our work. For us, respect means being open, honest and transparent, enabling us to achieve our shared goals. The respect Ardmac employees have for each other extends across all levels and locations of our business. It shapes our culture. It supports the realisation of reasonable and realistic expectations too. As a business, we are proud to acknowledge our team’s efforts, and we respect the boundaries between personal and professional life in order to maintain a healthy work-life balance.

Working Smart: Driving innovation in the world’s most advanced industries.

Technological advancement and the development of our expertise are essential components of Ardmac’s success. We believe that through sustainable investment in these areas, we are investing in the catalysts that will ensure our future growth. Our clients work at the forefront of innovation. The innovative solutions we provide to them are built on trust, collaboration and technical expertise. For us, innovation isn’t just part of what we do, it sits at the very heart of everything we do. It enables us to be agile, efficient, and stay ahead of industry developments. For our clients, this translates to building their vision as smoothly and quickly as possible.

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WORKING SMART

“We see huge potential in automating routine tasks and reducing administrative burdens, empowering our people to spend more time focusing on what they do best – applying their expertise where it adds the most value. This will help us move faster, make better decisions, and deliver higher-quality outcomes for our clients, all while continuing to uphold the quality standards that have come to define Ardmac or, as we call it, ‘the Ardmac Way’.”

Fergus Nugent, Operations Director

WORKING SMART

Revolutionising construction site management. At Ardmac, innovation drives excellence. In 2024, we embarked on a transformative journey to enhance our site openings management process. While our workflows were already grounded in robust BIM implementation, we recognised the potential to elevate efficiency and safety by integrating cutting- edge technology. After evaluating both Virtual Reality (VR) and Augmented Reality (AR), we identified AR as the optimal solution for on-site applications. Unlike VR, which posed safety challenges, AR offered a practical and secure alternative, allowing teams to utilise tablets in the field. To ensure seamless integration, we selected GAMMA AR, a leading augmented reality tool compatible with Autodesk Construction Cloud and Procore. A rigorous proof of concept verified its compatibility with our systems, and our Digital Innovation Committee (DIC) approved the deployment. The DIC, composed of senior leaders across departments, ensures all digital processes align with Ardmac’s high standards for quality and innovation.

By integrating AR with BIM, Ardmac has set a new standard for construction efficiency and precision. Real-time visualisation and data synchronisation eliminated inefficiencies, reduced errors, and aligned on-site execution with design specifications. This innovative system exemplifies our commitment to excellence, empowering teams with cutting-edge tools to deliver safer, more efficient, and higher- quality construction projects. Ardmac continues to lead the way in digital transformation, demonstrating how technology can revolutionise site management and redefine industry benchmarks.

“Our clients are building the future, and they trust us to deliver their vision. They value our dedication and commitment to ensuring that every project we deliver is of the highest quality.”

Enda Murphy, Chief Business Officer

Investing in Innovation: Ardmac’s commitment to R&D.

At Ardmac, innovation is more than a value, it’s a strategic priority. As technology reshapes the way we design, deliver, and operate high-performance environments, we are doubling down on our investment in research and development to lead from the front. We are entering a transformative chapter, embracing digitalisation, AI, and real-time data to enhance how we work, and how our clients benefit. With live project data and intelligent automation at our fingertips, our teams are making smarter decisions, faster, and with greater consistency than ever before.

AI and Smart Construction Ardmac is investing significantly in artificial intelligence as a cornerstone of our future delivery model. These tools are already driving measurable improvements in project efficiency, quality, and reliability enabling us to meet rising customer expectations in speed, precision, and transparency. Looking Forward, Delivering More We are proud of our 50-year legacy of delivering for our clients, and our eyes are firmly set on the next 50. In the coming years, Ardmac will more than double its investment in R&D, expanding our capabilities to support new sectors, explore new territories, and bring smarter, faster, and more sustainable solutions to every client.

INNOVATION

“Innovation at Ardmac isn’t just about adopting new tools, it’s about reimagining how we deliver value for our clients. As we integrate AI, live data, and digital construction technologies, we’re creating smarter, faster, and more resilient ways of working. The impact is already clear: greater efficiency, improved consistency, and a stronger foundation for the future. Over the next five years, our increased investment in R&D will allow us to lead in new sectors, enter new markets, and help our clients meet their most ambitious goals with confidence.”

Peter Lonergan, Associate Director - Pre-Construction & Innovation

Ethically and responsibly managing all aspects of our operations.

For us, sustainability is so much more than something we aspire towards—it’s embedded in our culture. We have now successfully integrated sustainability into our long-term strategy and our daily operations. We believe that the choices we make today will have a lasting impact. We also know that we’re not quite there yet and we have much more to do, but we are resolutely committed to fostering a cleaner, greener future for generations to come. Through our dedicated environmental, social, and governance (ESG) programme, Sky Blue, Ardmac is moving forward with purpose and responsibility, as we strive to create meaningful change in our industry.

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“It’s taken time but our sustainable practices are now firmly embedded in our corporate agenda. We don’t just talk about sustainability, there’s real substance behind our actions, and we aim to have authentic, transparent conversations about our progress along the way.”

Diarmaid Magee, Director of SHEQ

SUSTAINABILITY

Sustainability in Action From modelling embodied carbon on all projects to developing a sustainability labelling system for modular builds, we help clients make informed, low-carbon choices. Our in-house BIM team supports this by prioritising sustainable materials and smarter design.

Driving Industry-Wide Impact

Sustainability extends beyond our business. We collaborate with suppliers, setting higher environmental standards. Partnering with Dagard, we secured Environmental Product Declarations (EPDs) for cleanroom materials, setting a new industry benchmark. Achieving ISO 20400 certification in sustainable procurement reinforces our commitment. By prioritising ethical sourcing and encouraging suppliers to adopt EPDs, we drive positive change across the industry.

At Ardmac, sustainability isn’t just responsibility—it’s action.

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Ardmac is proud to announce a significant improvement in our 2025 EcoVadis Scorecard results, showcasing our commitment to sustainability and responsible business practices. Our overall score increased by 7 points, elevating us into the 80th percentile—a testament to our dedication to continuous progress. Our biggest strides were in Sustainable Procurement (+18 points) and Environmental Sustainability (+10 points), reflecting our strong focus on ethical sourcing and eco-friendly practices. With our improved ranking, we are now within reach of the Silver EcoVadis Medal, further reinforcing our position as a sustainability leader. While we celebrate these achievements, we remain committed to further enhancing our efforts, ensuring continuous improvement at every turn.

SUSTAINABILITY

+7 2025 Overall Score Improvement: Increased from 58/100 in 2024 to 65/100 in 2025 +18 Sustainable Procurement: Largest gain, rising 18 points from 40/100 to 58/100 +5 Labor & Human Rights Score: Improved 5 points, from 60/100 to 65/100

80 th Moved from the 68th percentile to the 80th percentile +10 Environment Score: Increased 10 points, from 60/100 to 70/100

FEB 2025

PHARMA CASE STUDY

Design & build, medical device cleanroom Design & Build Turnkey Cleanroom in an existing facility, consisting of approximately 3500 square meters

Client:

Confidential

Location:

Waterford, Ireland

Project Size:

3500 sqm

Ardmac were contracted to provide a Design & Build Turnkey Cleanroom in an existing facility, consisting of approximately 3500 square meters of ISO 8 Cleanroom, non-classified White Room, fit out of offices, meeting rooms and staff facilities for one of our global Medical Device clients in Waterford. Our architectural and structural scope involved the design and construction of a new mezzanine floor for the offices and new gantry cranes to service the cleanroom areas. Our design prioritised safety by implementing robust fire safety measures throughout the facility. The dividing firewalls, including all fire rated windows and doors along the firewall, compartmentalised the two cleanrooms and office areas, allowing suppression systems to protect neighbouring rooms, effectively enhancing overall safety. Our mechanical scope involved the design, supply, and installation of all mechanical services within the Cleanroom and offices areas, including HVAC systems, a compressed air system with strategically located live tap-ins throughout the Cleanroom facility, a central vacuum system with conveniently located inlets, cold and potable water supplies, drainage and sprinkler. Our electrical scope of work encompassed the design, supply, and installation of all electrical services within the Cleanroom and offices areas, including distribution boards, distribution systems, HVAC control cabling, general services, specialist cleanroom light fittings controlled through ceiling- mounted Passive Infrared Sensors (PIRs), and equipped with a Central Battery-backed Emergency Lighting System.

Ardmac demonstrated ingenuity on the project by incorporating specifically designed service plates. These plates provide the critical services needed for the client’s equipment, in a flexible solution allowing for the seamless movement of equipment in and out of the facility. This flexibility is crucial for the client, allowing them to adapt to changing technological needs, providing the ability to replace outdated machinery with new equipment without disruption. For this project, Ardmac used the latest technologies such as BIM to generate a clash free model, LEAN processes to bring value to the client and the use of integrated scheduling coupled with strong Project Management. David Buckley, Project Manager on the Waterford site tells us, ‘It is as important as anything else in the project to ensure that the client has trust in what we are doing’. Ardmac earns that trust by consistently delivering high-quality results that meet and exceed expectations. Our approach adds value to any cleanroom construction project and that is why Ardmac has become a trusted partner in the industry.

CASE STUDIES

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MEDTECH CASE STUDY

Bio-medical manufacturing cleanroom Design development, design coordination and construction of Bio-medical manufacturing cleanroom space to ISO 6/7 standard. Client: Boston Scientific Location: Clonmel, Tipperary, Ireland Project Size: 3,700 m2 Duration: 10 weeks

Phase 2: Cleanroom Production Facility The second phase converted office space into a state-of-the-art cleanroom, complete with gowning and material anti-lock rooms. This involved demolishing existing spaces, stripping out M&E services, and installing advanced systems, including HEPA filters, AHUs, lighting, and access controls. The architectural fit-out featured cleanroom ceilings, vinyl flooring, fire-rated doors, and stainless-steel fixtures. Externally, a corridor extension added a new employee entrance and three offices. This work, completed in just 10 weeks, included drainage, structural steelwork, roofing, cladding, and curtain walling. Operating within an active pharmaceutical site required meticulous planning, strict safety protocols, and minimal disruption. Controlled access and hygiene adherence were paramount. The project delivered a modern, functional, and sustainable facility, enhancing Boston Scientific’s operations while fostering employee well-being.

As part of Boston Scientific’s expansion in Clonmel, the project aimed to upgrade workplace facilities, expand lab and production areas, and establish seamless connections between new and existing spaces. The company sought a construction partner capable of delivering top- tier results in a live pharmaceutical environment. Ardmac’s expertise in operational settings and SMART processes made us the ideal choice. Phase 1: Agile Office Fit-Out The first phase transformed unused first-floor space into a modern, agile office. Key upgrades included raised access floors, partitions, glazing, bespoke joinery, acoustic meeting pods, and industrial- style finishes. A four-pipe coil system and sprinkler installation ensured energy-efficient heating and cooling. The design, aligned with Boston Scientific’s global standards, featured biophilic elements, acoustic baffles, felt walls, and a white noise system to promote comfort, focus, and well-being. A new toilet block with accessible, sleek facilities complemented the office fit-out.

CASE STUDIES

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HEALTHCARE CASE STUDY

BSL 2 modular isolation ward Design, build and commissioning of a 210m2 BSL 2 Cleanroom Modular off site constructed Isolation ward Client: Crumlin Childrens Hospital Location: Dublin, Ireland Project Size: 210 m2

Ardmac was selected to design, build, and commission a 210m² BSL-2 cleanroom isolation ward, constructed using modular off-site techniques. This state-of-the-art facility was specifically designed to provide a safe and controlled environment for the treatment of immune-deficient patients, ensuring the highest standards of infection control and patient care. Scope of Services As a full turnkey project, Ardmac managed every aspect of the build, from initial design to final commissioning. The scope included the construction of the building envelope, complete internal fit-out, installation of advanced mechanical and electrical (M&E) systems, and the integration of specialised control systems. Additionally, the project encompassed the supply and installation of furniture, ensuring a fully operational and functional facility upon completion.

Project Details The self-contained unit was strategically located within an enclosed courtyard at the center of the main hospital. Its placement required precise planning and logistical coordination to minimize disruption to hospital operations during construction and installation. To seamlessly integrate the new ward with the existing hospital infrastructure, a link corridor was constructed, providing direct access for staff and patients. The modular off-site construction approach offered significant advantages, including reduced on- site construction time, minimal disruption to the hospital environment, and enhanced quality control. Each module was prefabricated in a controlled environment, ensuring precision and compliance with stringent cleanroom standards before being transported and assembled on-site. The completed facility combines cutting-edge design, advanced technology, and meticulous craftsmanship to deliver a safe, efficient, and sustainable solution. By addressing the unique needs of immune-deficient patients, the project underscores Ardmac’s expertise in delivering high- quality healthcare environments that prioritise patient safety and operational excellence.

CASE STUDIES

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PHARMA CASE STUDY

WuXi Biologics Detailed design assist with execution including project management, procurement and installation. Client: WuXi Biologics Location: Dundalk, Ireland Project Size: 15,000m²

Ardmac were contracted to complete a full cleanroom installation within two buildings on the WuXi Biologics site in Dundalk. The project involved detailed design assist with execution including project management, procurement and installation of all architectural elements within the cleanroom envelope. This included but not limited to Modular Ceilings including lights and grilles walls, double flush vision panels, doors, furniture, flooring and stainless steel protections. The scope also included door Automation and interlock Controls along with eight number downflow booths for client processes and manufacturing.

The walk-on ceiling system was designed and installed to facilitate 1.5kN/m² and 2.5kN/gm² at varying locations to complete the Ardmac supply and install interstitial area Handrails, edge Protection and stair units. The cleanroom floor installations complimented a flush floor finish interface with wall panels, furniture and client equipment. The cleanroom scope spanned 15,000m² with Grade C, Grade D and CNC room classifications. As part of design development and field execution a significant amount of trade partner constructability and coordination reviews were held focusing on the build sequencing and timing for planned works.

CASE STUDIES

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PHARMA CASE STUDY

API Architectural Envelope Design Build Turnkey Package for a Quality Control Laboratory Client: Confidential Location: Ireland Project Size: 1450 sqm

Ardmac were entrusted with a Design Build Turnkey Package for a Quality Control Laboratory associated with a new API (Active Pharmaceutical Ingredient) facility in Ireland. In addition to this scope, Ardmac were awarded the Architectural envelope of the cleanroom facility and a critical containment facility blast wall. This comprehensive undertaking encompassed various crucial components, including a Quality Control (QC) Laboratory, Filter Drier, Scrubber, Solution Preparation area, and a spacious multi- level Process Ballroom, complete with numerous supporting rooms across three floors. Ardmac played a pivotal role in the initial design and subsequent construction phases, addressing structural, architectural, mechanical, and electrical aspects of the cleanroom and laboratory package. Collaborating with specialist trade partners and under the supervision of Jacobs Engineering as Project Integrator, Ardmac ensured the seamless execution of the project. Integrated Approach & Blast Wall Ardmac optimized constructability by identifying secondary steel needs early, ensuring compliance with blast and fire ratings. The 18m-high, 1000sqm blast wall (50Kn/M2) met stringent safety standards while accommodating over 250 service penetration points for current and future process needs. Key Installations Ardmac designed, supplied, and installed the full HVAC system for the QC Laboratory, including AHUs, extract systems, and integrated CAV/VAV controls. Electrical work covered distribution boards, lighting, HVAC control cabling, and specialist cleanroom fittings with PIR sensors and emergency lighting.

Safety & Containment A bespoke door interlock system was integrated with decontamination misting showers and automated doors, ensuring security in high-containment ATEX areas. Ardmac also installed lab furniture, fume hoods, and chemical storage, using Dagard walls, ceilings, and doors to maintain containment in line with VDI 2083 Part 19 standards. Commissioning & Compliance Rigorous testing ensured compliance with client safety standards, including independent containment validation under VDI 2083. Ardmac developed early design assessments and SATs, supporting the qualification process for safe HVAC and fume hood operation. Conclusion This project showcased Ardmac’s expertise in delivering high-spec pharmaceutical facilities. Our integrated approach, collaboration with trade partners, and commitment to safety ensured a successful outcome, meeting OEB 5 product requirements and global industry standards.

CASE STUDIES

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PHARMA CASE STUDY

Modular mRNA Manufacturing Facility Multi Module 40Ft Containments Client: Modular mRNA Manufacturing Facility in Africa Location: Rwanda

Ardmac partnered with Germfree to deliver two modularised vaccine manufacturing suites for a multinational pharmaceutical client. The first project, situated in Germany, was completed in two phases as a proof of concept, achieving a Percentage Manufactured Value of 78% of works completed offsite. A second project was then commissioned with Germfree to deliver suites into central Africa, with the PMV achieving 98% of works completed offsite, including full factory acceptance testing and commissioning. During development of project two, our design time decreased by 50% as the scheme was proven as a flexible and scalable solution through the adaption of a standardised and repeatable design. As we developed the project together with our client team, improvements were tabled and implemented allowing the total time spent on site with the installation of the modules to reduce from 12 weeks on Phase One to 4 weeks on Phase Two. This joint learning and development supported our client to honour their commitment to deliver facilities to an African state in 2022; a historic event for the continent and humanity as we responded to the global pandemic of Covid-19. The Germfree Modular Cleanrooms are fully self-contained pharmaceutical facilities which are scalable to suit clients’ needs, transportable globally due to their standard 40-foot container size and customisable to our clients processes and requirements. To date, Germfree have delivered multiple modular cleanrooms to clients within Ireland, Mainland Europe, and to the continent of Africa. To demonstrate our versatility, we chartered the Antonov AN124, one of the largest cargo planes currently available globally, to transport the first of the modular units into Rwanda.

The significance of this delivery was a major political event for the African Union highlighting the speed at which these modular facilities can be deployed globally, using various means of transport to achieve the required goals, to regions that would not be traditionally considered for pharmaceutical facilities. The launch of the Modular Cleanrooms bound for Africa by our client was attended by senior leaders of WHO (World Health Organisation) as well as several Presidents and Prime Ministers from the African Union, European Union and other global dignitaries, all of which received significant media coverage.

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PHARMA CASE STUDY

University of Cardiff Supply, installation and commissioning of the cleanroom systems for the ICS Cleanroom.

Client:

Cardiff University

Location:

Cardiff, UK

Ardmac were employed as the Cleanroom Contractor for University of Cardiff. The package consisted of the supply, installation and commissioning of the cleanroom systems for the ICS Cleanroom. This consisted of ceilings, including lights and blank pans; walls and doors; raised access floor; gowning areas; fan filter units; walk-on plenum grid system; plenum dividers underfloor between clean bays and equipment chases and ducted ULPA filter modules. Ardmac were responsible for the detailed surveying of the relevant part of the existing building and the setting out of construction to suit site conditions. The detailed development of the design for the cleanroom fabric components (walls, floor, ceiling, etc.) were also part of the scope. This included working closely with AED during the stafe 4A, through 4C detailed design, working in the same Revit model to a level of detail of 300.

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Daniel, CRB

Jonathan Curwen Senior Design Manager, Construction North East “Having worked with the Ardmac design team for several months, Wates found them to be highly motivated in providing ourselves and the Client with an experienced team of Designers who work collaboratively within the wider project design team, utilising project specific BIM requirements. Information was issued to the agreed timescales and to a high standard to enable detailed reviews to be undertaken, and finalised details and agreements to be made with the Client prior to conclusion of the design process. Ardmac’s deep knowledge and understanding of the proposed products has helped understand other key secondary work elements.”

“We were thrilled to partner with Ardmac on this project. From the outset, their reliability and commitment to doing the right thing for the project’s success were evident. This was CRB’s first time working with Ardmac, and given our highly compressed schedule for a groundbreaking product, trust was crucial. Both teams established a strong foundation of trust early on, which proved invaluable and delivered results quickly. The Ardmac team made the entire process seamless, and we truly enjoyed working with them. We look forward to collaborating with Ardmac again on future projects.”

CLIENT REFERENCES

Ali Masood DTX Manager

Senior Manager Fluor

“Ardmac has recently delivered two Cleanrooms for us – our idea came into existence on an A4 paper which was executed professionally by the brilliant Ardmac team. This project couldn’t have been delivered better and this is only because of the total commitment of all the people involved and their extensive knowledge. I am thoroughly happy. Thank you, Ardmac & Team!”

“We are extremely satisfied with Ardmac’s performance as a supplier. Your dedication and consistent delivery of high-quality products on schedule have been crucial to the this Project. Thank you for your responsiveness to our inquiries and proactive communication about potential delays or issues, which have helped us plan effectively and maintain smooth workflows. We look forward to working with you again in the future.”

Our clients work at the forefront of innovation.

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Get in touch directly.

ENDA MURPHY Chief Business Officer

DECLAN HUGHES Associate Director Business Development Life Sciences

Business Enquiries

enda.murphy@ardmac.com +353 (0) 85 888 8340 www.ardmac.com

Declan.Hughes@ardmac.com +353 (0) 86 856 5528 www.ardmac.com

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