Only Credelio Quattro™ offers the broadest* parasite protection available in an isoxazoline endectocide. Unlike other endectocides, it protects against six types of parasites in one monthly flavored chewable tablet:
Ticks
Fleas
Heartworms
Roundworms Tapeworms *Based on label comparison of the number of parasite types covered in an isoxazoline endectocide. † Uncinaria stenocephala Hookworms †
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Indications: Credelio Quattro is indicated for the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of roundworm (immature adult and adult Toxocara canis and adult Toxascaris leonina ), hookworm (adult Uncinaria stenocephala ), and tapeworm ( Dipylidium caninum , Taenia pisiformis , and Echinococcus granulosus ) infections. Credelio Quattro kills adult fleas and is indicated for the treatment and prevention of flea infestations ( Ctenocephalides felis ) and the treatment and control of tick infestations [ Amblyomma americanum (lone star tick), Dermacentor variabilis (American dog tick), Ixodes scapularis (black-legged tick), and Rhipicephalus sanguineus (brown dog tick)] for one month in dogs and puppies 8 weeks of age and older and weighing 3.3 pounds or greater. Important Safety Information: Lotilaner, an ingredient in Credelio Quattro, belongs to the isoxazoline class and has been associated with neurologic adverse reactions like tremors, ataxia, and seizures even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. Dogs should be tested for existing heartworm infections before Credelio Quattro administration as it is not effective against adult D. immitis . The safe use in breeding, pregnant, or lactating dogs has not been evaluated. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea. See the Elanco Booth for full prescribing information. © 2025 Elanco. Credelio Quattro, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates. PM-US-24-2256
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