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September 19, 2024 VMR with Rabih & Maryana - tingling, numbness, and burning sensation of b/l LE
Correct Answer:
Diagnosis of seronegative NMOSD and initiation of immunosuppressive therapy
This patient presents with classic clinical features and MRI findings highly suggestive of NMOSD, despite being seronegative for both anti-AQP4 and anti-MOG antibodies. A diagnosis of NMOSD can still be made based on clinical and radiologic criteria, even in the absence of detectable antibodies, as seronegative NMOSD is a well- recognized subset. Early recognition and initiation of immunosuppressive therapy are critical to preventing relapses and reducing the risk of long-term disability.
EP I
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