Neurologic examination: she was awake and didn’t speak, with sporadic growling. She also had impaired swallowing and apparent muscle stiffness, although limbs could be passively moved
subfebrile Buzzwords
autonomic instability
Catatonia
central hypoventilation
subacute
pseudoviral
personality changes
Orofacial dyskinesias
Dx/DDx: Time course + Localization
Unspecific prodrome
Psychiatric symptoms
Movement disorder
Final DX
Anti-NMDA receptor encephalitis
Serology
Basic labs & toxicology screen To review potential toxic/metabolic causes
Pelvic US
Imaging
CSF analysis
autoimmune encephalitis pannel
to look for a potential tumor on the ovaries
To look por signs of inflammation and antibodies (anti- NMODAr among others)
To look por patterns of inflammation (i.e. limbic encephalitis)
Aprox. 50% of patients have a unilateral ovarian teratoma
Anti-NMDA testing is more sensitive in the CSF rather than serum. It is not always the case for antibody-mediated encephalitis
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