2027 Express Scripts National Preferred Formulary

(continued)

DRUG CLASS

EXCLUDED MEDICATIONS

PREFERRED ALTERNATIVES

Sickle Cell Disease Agents Thrombocytopenia Agents

SIKLOS, XROMI

hydroxyurea, DROXIA

ALVAIZ

eltrombopag, DOPTELET, NPLATE

MULPLETA WAYRILZ AQVESME

DOPTELET

eltrombopag, DOPTELET, NPLATE, TAVALISSE Coverage may be approved for the treatment of Alpha-Thalassemia, Transfusion-dependent Beta-Thalassemia or Non-Transfusion-dependent Beta-Thalassemia under certain conditions. Coverage may be approved for the treatment of Myelodysplastic Syndrome with Transfusion- Dependent Anemia under certain conditions. EPCLUSA, HARVONI, LEDIPASVIR/SOFOSBUVIR, SOFOSBUVIR/VELPATASVIR, VOSEVI EPCLUSA, SOFOSBUVIR/VELPATASVIR, VOSEVI atazanavir, darunavir, fosamprenavir, lopinavir/ ritonavir, ritonavir, PREZISTA Coverage may be approved for the treatment of Human Immunodeficiency Virus-1 Infection in heavily treatment-experienced patients with multidrug-resistant infection.

Miscellaneous Hematology Agents

RYTELO

HEPATITIS Hepatitis C

MAVYRET

SOVALDI

HIV Antiretrovirals Note: Current patients established on therapy are allowed to continue therapy.

PREZCOBIX

RUKOBIA ER

STRIBILD

BIKTARVY, GENVOYA colchicine, MITIGARE

MUSCULOSKELETAL AND RHEUMATOLOGY Gout Therapy Muscle Relaxants and Antispasmodic Agents

GLOPERBA

ATMEKSI, METHOCARBAMOL 1,000MG TABLETS methocarbamol 500mg tablets

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

COMBOGESIC

ibuprofen plus acetaminophen

COXANTO, DICLOFENAC 35MG CAPSULES, DOLOBID, FENOPROFEN 200MG CAPSULES, FENOPRON, OXAPROZIN 300MG CAPSULES, RELAFEN DS, SPRIX, ZORVOLEX

generic oral nonsteroidal anti-inflammatory drugs

ELYXYB, VYSCOXA

celecoxib

MELOXICAM SUSPENSION, ZYBIC DICLOFENAC EPOLAMINE PATCHES

ibuprofen suspension, naproxen suspension

Topical Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

FLECTOR, LICART

OBSTETRICAL AND GYNECOLOGICAL Combination Patches

CLIMARA PRO

COMBIPATCH

Contraceptives

AVERI, FEMLYV, LO LOESTRIN FE, NATAZIA, NEXTSTELLIS, TWIRLA, TYBLUME

generic oral, patch and ring contraceptives

PHEXX

Barrier methods of contraception, such as condoms, diaphragms or spermicides.

SLYND

generic progestin-only oral contraceptives

Estrogen and Estrogen Modifiers for Vaginal Symptoms

ESTRING, IMVEXXY, INTRAROSA, OSPHENA estradiol cream, estradiol vaginal inserts, PREMARIN CREAM FEMRING

estradiol cream, estradiol patches, estradiol tablets, estradiol vaginal inserts, PREMARIN CREAM estradiol/norethindrone acetate, ethinyl estradiol/ norethindrone acetate conjugated estrogen tablets, estradiol tablets

Estrogen/Progestin Combinations (Oral)

BIJUVA, PREMPHASE, PREMPRO

Estrogens (Oral)

MENEST

Human Chorionic Gonadotropin

CHORIONIC GONADOTROPIN 10,000 UNITS, NOVAREL

OVIDREL, PREGNYL

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