2027 Express Scripts National Preferred Formulary

(continued)

DRUG CLASS

EXCLUDED MEDICATIONS

PREFERRED ALTERNATIVES

Short-Acting Beta2-Agonist Inhalers

ALBUTEROL SULFATE HFA (by Prasco), LEVALBUTEROL HFA, PROAIR RESPICLICK, VENTOLIN HFA, XOPENEX HFA

albuterol sulfate hfa (all manufacturers covered except Prasco)

MISCELLANEOUS AGENTS Allergen Immunotherapy

PALFORZIA

Coverage may be approved for the treatment of Peanut Allergy under certain conditions. Coverage may be approved for the treatment of Barth Syndrome under certain conditions.

Barth Syndrome Agents

FORZINITY

Benign Prostatic Hyperplasia Agents

ENTADFI TEZRULY

finasteride 5mg plus tadalafil 5mg

terazosin

Botulinum Toxin Products

BOTOX

DYSPORT, MYOBLOC Migraine — AIMOVIG, AJOVY, EMGALITY, QULIPTA Hyperhidrosis — Over-the-Counter aluminum chloride containing products

DAXXIFY, XEOMIN

DYSPORT, MYOBLOC

Cardiomyopathy and Polyneuropathy of Hereditary Transthyretin-Mediated Amyloidosis

AMVUTTRA

HTTR-C: VYNDAMAX Coverage may be approved for treatment of Polyneuropathy of Hereditary Transthyretin- Mediated Amyloidosis (hATTR) under certain conditions.

ATTRUBY

VYNDAMAX

ONPATTRO, WAINUA

Coverage may be approved for treatment of Polyneuropathy of Hereditary Transthyretin- Mediated Amyloidosis (hATTR) under certain conditions.

Complement Inhibitors

BKEMV, PIASKY, SOLIRIS, ULTOMIRIS

ENSPRYNG, EPYSQLI

Eosinophilic Esophagitis Agents

EOHILIA

budesonide suspension made into a slurry or suspension and swallowed (not inhaled) avanafil, sildenafil, tadalafil, vardenafil duloxetine dr (20mg, 30mg, 40mg, 60mg), milnacipran, pregabalin

Erectile Dysfunction Fibromyalgia Agents

VYBRIQUE

TONMYA

Folic Acid Products

FOLIC ACID ORAL SOLUTION, QUIOFIC

folic acid tablets

Gaucher Disease Agents

ELELYSO, VPRIV

CEREZYME

Glucocorticoids

ALKINDI SPRINKLE, KHINDIVI

hydrocortisone tablets dexamethasone tablets CINRYZE, RUCONEST

DEXLYT, HEMADY

Hereditary Angioedema

BERINERT DAWNZERA

ANDEMBRY, HAEGARDA, TAKHZYRO

EKTERLY AVLAYAH

icatibant

Hunter Syndrome Agents

Coverage may be approved for the treatment of Mucopolysaccharidosis Type II (Hunter syndrome) under certain conditions.

Hypoactive Sexual Desire Disorder Agents

ADDYI

VYLESSI

Immune Globulins

CUTAQUIG

SC: GAMMAGARD LIQUID, GAMMAGARD LIQUID ERC, GAMUNEX-C, XEMBIFY IV: GAMMAGARD LIQUID, GAMMAGARD LIQUID ERC, GAMMAGARD S-D, GAMUNEX-C SC: GAMMAGARD LIQUID, GAMMAGARD LIQUID ERC, GAMUNEX-C, XEMBIFY

GAMMAKED, GAMMAPLEX, PANZYGA, QIVIGY, YIMMUGO

© 2026 Evernorth Health Services. All rights reserved. All trademarks are the property of their respective owners. CRP1584203A 204612 NP Excl (08/01/2026)

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