UHPLC/HPLC Columns
Shim-pack Scepter LC Columns
Excellent stability & performance could be achieved under a wide range of LC conditions Excellent stability and performance could be achieved under a wide range of LC conditions with Shim-pack Scepter LC columns, which are the next generation organic silica hybrid based columns. With different chemistry characteristics, Shim-pack Scepter columns are effective for method development/scouting with suitability for use in a wide variety of applications. With different particle sizes (1.9 µm, 3 µm, 5 µm) and different column dimensions, Shim-pack Scepter LC columns are fully scalable between UHPLC, HPLC and preparative LC making method transfer seamless between different laboratory instrumentation.
Shim-pack Scepter Chemistries
Reversed Phase
HILIC
Shim-pack Scepter
C18
HD-C18
C8
Pheny
PFPP
C4
Diol-HILIC
Trifunctional C18 Trifunctional C18
Trifunctional Phenylbutyl
Trifunctional Pentafluorophenylpropyl
Trifunctional Dihydroxypropyl
Ligand Type
Trifunctional C8
Butyl group
Generic Purpose Type
High Density Type
Particle
Organic Silica Hybrid
Particle Size
1.9 μm, 3 μm, 5 μm
Pore Size
12 nm
8 nm
12 nm
30 nm
12 nm
End Capping
Proprietary
None
Proprietary
None
pH Range
1 - 12
1 - 10
1 - 8
1 - 10
2 - 10
100% aqueous condition
Yes
No
No
Yes
Yes
No
N/A
USP Classification
L1
L1
L7
L11
L43
L26
L20
Method Scouting Utilize excellent stability & performance under a wide range of LC conditions
With excellent stability under a wide range of LC conditions, Shim-pack Scepter LC columns are effective for method scouting combining mobile phase pH and organic modifier.
Comparison of Chromatograms using Gradient condition with Acetonitrile
Analytes 1. Saccharin (pKa = 2.2) 2. Dextromethorphan (pKa = 8.3) 3. Amitriptyline (pKa = 9.4) 4. N-Butyl paraben (pKa = 8.3) 5. Ibupurofen (pKa = 4.4)
For Shim-pack Scepter C4, please refer to page A-22
Pg A-15
Made with FlippingBook Digital Proposal Creator